Second-site mutation outside of the Us10-12 domain of δγ134.5 Herpes simplex virus 1 recombinant blocks the shutoff of protein synthesis induced by activated protein kinase r and partially restores neurovirulence

Journal of Virology

Volumn 76, Issue 3, 2002, Pages 942-949

  Cassady, Kevin A ^a   Gross, Martin ^a   Gillespie, G Yancey ^a   Roizman, Bernard ^a  

^a UNIVERSITY OF CHICAGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATED PROTEIN KINASE R; GENE PRODUCT; INITIATION FACTOR 2; INITIATION FACTOR 2ALPHA; INTERFERON; PROTEIN KINASE; RECOMBINANT PROTEIN; UNCLASSIFIED DRUG; VIRUS PROTEIN;

ANIMAL CELL; ANIMAL EXPERIMENT; ARTICLE; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; FEMALE; GENE MAPPING; GENE MUTATION; HERPES SIMPLEX VIRUS 1; HUMAN; HUMAN CELL; MOUSE; NEUROLOGIC DISEASE; NONHUMAN; PHENOTYPE; PRIORITY JOURNAL; PROTEIN DEPHOSPHORYLATION; PROTEIN DOMAIN; PROTEIN SYNTHESIS; PROTEOMICS; REACTION ANALYSIS; VIRUS MUTANT; VIRUS MUTATION; VIRUS VIRULENCE;

EID: 0036145269     PISSN: 0022538X     EISSN: None     Source Type: Journal    
DOI: 10.1128/JVI.76.3.942-949.2002     Document Type: Article

References (30)

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