α1 connexin (connexin43) gap junctions and activities of cAMP-dependent protein kinase and protein kinase C in developing mouse heart

Developmental Dynamics

Volumn 223, Issue 1, 2002, Pages 96-107

  Duncan, John C ^a   Fletcher, William H ^a,b,c  

^a LOMA LINDA UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b Jerry L Pettis Memorial VA Medical Center   (United States)

^c VETERANS AFFAIRS MEDICAL CENTER   (United States)

Author keywords

Connexin43; Gap junctions; Heart development; Protein kinase A; Protein kinase C

Indexed keywords

CONNEXIN 43; CYCLIC AMP DEPENDENT PROTEIN KINASE; ISOENZYME; PHOSPHOTRANSFERASE; PROTEIN KINASE C;

AGE; ANIMAL TISSUE; ARTICLE; CATALYSIS; CONTROLLED STUDY; EMBRYO; EMBRYO PATTERN FORMATION; ENZYME ACTIVITY; ENZYME ASSAY; HEART DEVELOPMENT; IMMUNOBLOTTING; MOLECULAR WEIGHT; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM;

ANIMALS; CELL FRACTIONATION; CONNEXIN 43; CYCLIC AMP-DEPENDENT PROTEIN KINASES; FEMALE; GAP JUNCTIONS; HEART; IMMUNOBLOTTING; MALE; MICE; MYOCARDIUM; PHOSPHORYLATION; PREGNANCY; PROTEIN ISOFORMS; PROTEIN KINASE C;

EID: 0036140337     PISSN: 10588388     EISSN: None     Source Type: Journal    
DOI: 10.1002/dvdy.1232     Document Type: Article

References (51)

1. Antisera directed against connexin43 peptides react with a 43-kD protein localized to gap junctions in myocardium and other tissues
2. Mutations of the connexin43 gap-junction gene in patients with heart malformations and defects of laterality
3. Direct cytochemical localization of catalytic subunits dissociated from cAMP-dependent protein kinase in reuber H-35 hepatoma cells. II. Temporal and spatial kinetics
4. Phosphorylation of connexin43 gap junction protein in uninfected and Rous sarcoma virus-transformed mammalian fibroblasts
5. Misregulation of connexin43 gap junctions and pediatric heart disease
6. Identification of connexin43 (α 1) gap junction gene mutations in patients with hypoplastic left heart syndrome by denaturing gradient gel electrophoresis (DGGE)
7. The ε subtype of protein kinase C is required for cardiomyocyte connexin-43 phosphorylation
8. Heart and neural tube defects in transgenic mice overexpressing the Cx43 gap junction gene
9. Direct cytochemical localization of catalytic subunits dissociated from cAMP-dependent protein kinase in reuber H-35 hepatoma cells. I. Development and validation of fluoresceinated inhibitor
10. Recepter-mediated actions without receptor occupancy
11. Cytochemical identification of regulatory subunit from cAMP-dependent protein kinase by use of fluorescently-labeled catalytic subunit: Alterations in hepatoma cells responding to 8-Br-cAMP
12. Critical period of rat development when sidedness of asymmetric body structures is determined
13. Metabolic coupling, ionic coupling, and cell contacts
14. In situ regulation of cell-cell communication by the cAMP-dependent protein kinase and protein kinase C
15. Connexins, connexons, and intercellular communication
16. Synchronized beating of myocardial cells mediated by FL cells in monolayer culture and its inhibition by trypsin-treated FL cells
17. Independent expression of cardiac type I and II cyclic AMP-dependent protein kinase during murine embryogenesis and postnatal development
18. Gap junction-mediated cell-cell communication modulates mouse neural crest cell migration
19. Fluorescence resonance energy transfer within a heterochromatic cAMP-dependent protein kinase holoenzyme under equilibrium conditions: New insights into the conformational changes that result in cAMP-dependent activation
20. Assay and purification of protein kinase C
21. Isolation and characterization of the ε subspecies of protein kinase C from rat brain
22. The gap junction communication channel
23. Cleavage of structural proteins during the assembly of the head of bacteriophage T4
24. Biochemical and immunochemical analysis of the arrangement of connexin43 in rat heart gap junction membranes
25. Turnover and phosphorylation dynamics of connexin43 gap junction protein in cultured cardiac myocytes
26. Transmission of hormonal stimulation by cell-to-cell communication
27. Gap junctions are involved in the early generation of left-right asymmetry
28. Gap junctions-mediated transfer of left-right patterning signals in the early chick blastoderm is upstream of Shh asymmetry in the node
29. A molecular pathway determining left-right asymmetry in chick embryogenesis
30. The role of gap junction membrane channels in development
31. Regulation of the cellular and subcellular concentrations and distribution of cyclic nucleotide-dependent protein kinases
32. Human connexin43 gap junction channels. Regulation of unitary conductances by phosphorylation
33. Hormone-induced intercellular signal transfer dissociates cAMP-dependent protein kinase
34. Expression of the gap junction protein connexin43 in embryonic chick lens: Molecular cloning, ultrastructural localization, and post-translational phosphorylation
35. Biochemical analysis of connexin43 intracellular transport, phosphorylation, and assembly into gap junctional plaques
36. Selective monoclonal antibody recognition and cellular localization of an unphosphorylated form of connexin43
37. Selective permeability of different connexin channels to the second messenger inositol 1,4,5-trisphosphate
38. Developmental regulation of gap junction gene expression during mouse embryonic development
39. Developmental changes in cyclic AMP, protein kinase, phosphorylase kinase, and phosphorylase in liver, heart, and skeletal muscle of the rat
40. Isolation and characterization of the δ subspecies of protein kinase C from rat brain
41. Cardiac malformation in neonatal mice lacking connexin43
42. Connexin43 expression in the mouse embryo: Localization of transcripts within developmentally significant domains
43. Protein kinase C isoform expression and regulation in the developing rat heart
44. The hormone-induced regulation of contact-dependent cell-cell communication by phosphorylation
45. Expression of a Cx43/β-gal fusion protein inhibits gap junctional communication in NIH-3T3 cells
46. The inhibitor protein of cAMP-dependent protein kinase-catalytic subunit interaction: Parameters of complex formation
47. Chamber-related differences in connexin expression in the human heart
48. Substrate diversity of the cAMP-dependent protein kinase: Regulation based upon multiple binding interactions
49. A three-step purification procedure for protein kinase C: Characterization of the purified enzyme
50. Spatial and temporal patterns of distribution of the gap junction protein connexin43 during mouse gastrulation and organogenesis
51. Membrane topology and quaternary structure of cardiac gap junction ion channels