메뉴 건너뛰기




Volumn 64, Issue 12, 1996, Pages 5151-5160

Effector mechanisms responsible for gamma interferon-mediated host resistance to Legionella pneumophila lung infection: The role of endogenous nitric oxide differs in susceptible and resistant murine hosts

Author keywords

[No Author keywords available]

Indexed keywords

GAMMA INTERFERON; N(G) METHYLARGININE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; RECOMBINANT GAMMA INTERFERON;

EID: 0029852305     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.64.12.5151-5160.1996     Document Type: Article
Times cited : (44)

References (47)
  • 1
    • 0027417230 scopus 로고
    • Phenotypic modulation by Legionrlla pneumophila upon infection of macrophages
    • Abu Kwalk, Y., B. I. Eisenstein, and N. C. Engleberg. 1993. Phenotypic modulation by Legionrlla pneumophila upon infection of macrophages. Infect. Immun. 61:1320-1329.
    • (1993) Infect. Immun. , vol.61 , pp. 1320-1329
    • Abu Kwalk, Y.1    Eisenstein, B.I.2    Engleberg, N.C.3
  • 2
    • 0023000775 scopus 로고
    • Interferon gamma activated human monocytes inhibit intracellular multiplication of Legionella pneumophila
    • Bhardwaj, N., T. W. Nash, and M. A. Horwitz. 1986. Interferon gamma activated human monocytes inhibit intracellular multiplication of Legionella pneumophila. J. Immunnl. 137:2662-2669.
    • (1986) J. Immunnl. , vol.137 , pp. 2662-2669
    • Bhardwaj, N.1    Nash, T.W.2    Horwitz, M.A.3
  • 3
    • 0023946308 scopus 로고
    • Protective effects of tumor necrosis factor in experimental Legionella pneumophila infections in mice via activation of PMN function
    • Blanchard, D. K., J. Y. Duey, T. W. Klein, H. Friedman, and W. E. Stewart. 1988. Protective effects of tumor necrosis factor in experimental Legionella pneumophila infections in mice via activation of PMN function, J. Leukocyte Biol. 43:429-435.
    • (1988) J. Leukocyte Biol. , vol.43 , pp. 429-435
    • Blanchard, D.K.1    Duey, J.Y.2    Klein, T.W.3    Friedman, H.4    Stewart, W.E.5
  • 4
    • 0024333889 scopus 로고
    • Induction of Interferon gamma and tumor necrosis factor by L. pneumophila: Augmentation of human neutrophil bacteriocidal activity
    • Blanchard, D. K., H. Friedman, T. W. Klein, and J. Y. Djeu. 1989. Induction of Interferon gamma and tumor necrosis factor by L. pneumophila: augmentation of human neutrophil bacteriocidal activity. J. Leukocyte Biol. 45:538-545.
    • (1989) J. Leukocyte Biol. , vol.45 , pp. 538-545
    • Blanchard, D.K.1    Friedman, H.2    Klein, T.W.3    Djeu, J.Y.4
  • 5
    • 0023186964 scopus 로고
    • Cytolytic activity of human peripheral Wood leukocytes against Leginella pneumophila-infected monocytes; characterization of the effector cell and augmentation by interleukin-2
    • Blanchard, D. K., W. E. Stewart, T. W. Klein, H. Friedman, and J. Y. Djeu. 1987. Cytolytic activity of human peripheral Wood leukocytes against Leginella pneumophila-infected monocytes; characterization of the effector cell and augmentation by interleukin-2. J. Immunol. 139:551-556.
    • (1987) J. Immunol. , vol.139 , pp. 551-556
    • Blanchard, D.K.1    Stewart, W.E.2    Klein, T.W.3    Friedman, H.4    Djeu, J.Y.5
  • 6
    • 0002834378 scopus 로고
    • Modes of transmission in epidemic and nonepidemic Legionella infection: Directions for further study
    • J. M. Burbaree, R. F. Breiman, and A. P. Dufour (ed.), American Society for Microbiology, Washington
    • Breiman, R. F. 1993. Modes of transmission in epidemic and nonepidemic Legionella infection: directions for further study, p. 30-35. In J. M. Burbaree, R. F. Breiman, and A. P. Dufour (ed.), Legionella: current status und emerging perspectives. American Society for Microbiology, Washington.
    • (1993) Legionella: Current Status und Emerging Perspectives , pp. 30-35
    • Breiman, R.F.1
  • 7
    • 0028079788 scopus 로고
    • Replicative Legionella pneumophila lung infection in intratrachcally inoculated A/J mice. A muirine model of human Legionnaires' disease
    • Brieland, J. K., P. Freeman, R. Kunkel, C. Chrisp, M. Hurley, J. Fanlone, and C. Engleberg. 1994. Replicative Legionella pneumophila lung infection in intratrachcally inoculated A/J mice. A muirine model of human Legionnaires' disease. Am. J. Pathol. 145:1537-1546.
    • (1994) Am. J. Pathol. , vol.145 , pp. 1537-1546
    • Brieland, J.K.1    Freeman, P.2    Kunkel, R.3    Chrisp, C.4    Hurley, M.5    Fanlone, J.6    Engleberg, C.7
  • 8
    • 0029162728 scopus 로고
    • In vivo regulation of replicativc Legionella pneumophila lung infection by endogenous tumor necrosis factor alpha and nitric oxide
    • Brieland, J. K., D. U. Remick, P. Freeman, M. C. Hurley, J. C. Fantone, and N. C. Engleberg. 1995. In vivo regulation of replicativc Legionella pneumophila lung infection by endogenous tumor necrosis factor alpha and nitric oxide. Infect. Immun. 63:3253-3258.
    • (1995) Infect. Immun. , vol.63 , pp. 3253-3258
    • Brieland, J.K.1    Remick, D.U.2    Freeman, P.3    Hurley, M.C.4    Fantone, J.C.5    Engleberg, N.C.6
  • 9
    • 0024555386 scopus 로고
    • Interferon gamma-activated human monocytes downregulute transferrin receptors and inhibit the intracellular multiplication of Legionella pneumophila by limiting the availability of Iron
    • Byrd, T. F., and M. A. Horwitz. 1989. Interferon gamma-activated human monocytes downregulute transferrin receptors and inhibit the intracellular multiplication of Legionella pneumophila by limiting the availability of Iron. J. Clin. Invest. 83:1457-1465.
    • (1989) J. Clin. Invest. , vol.83 , pp. 1457-1465
    • Byrd, T.F.1    Horwitz, M.A.2
  • 11
    • 0022507071 scopus 로고
    • Separation of Legionella pneumophila proteases and purification of a protease which produces lesions like those of Legionnaires' disease in guinea-pig lung
    • Conlan, J. W., A. Baskerville, and I. A. E. Ashworth. 1986. Separation of Legionella pneumophila proteases and purification of a protease which produces lesions like those of Legionnaires' disease in guinea-pig lung. J. Gen. Microbiol. 132:1565-1574.
    • (1986) J. Gen. Microbiol. , vol.132 , pp. 1565-1574
    • Conlan, J.W.1    Baskerville, A.2    Ashworth, I.A.E.3
  • 12
    • 0023905942 scopus 로고
    • In vim production of a tissue-destructive protease by Legionella pneumophila in the lungs of experimentally infected guinea pigs
    • Conlan, J. W., A. Williams, and L. A. E. Ashworth. 1988. In vim production of a tissue-destructive protease by Legionella pneumophila in the lungs of experimentally infected guinea pigs. J. Gen. Microbiol. 134:143-149.
    • (1988) J. Gen. Microbiol. , vol.134 , pp. 143-149
    • Conlan, J.W.1    Williams, A.2    Ashworth, L.A.E.3
  • 13
    • 0027993994 scopus 로고
    • Experimental murine pulmonary cryptococcosis. Differences in pulmonary inflammation and lymphocyte recruitment induced by two encapsulated strains of Cryptococcus neufomans
    • Curtis, J. L., G. B. Huffhagle, G. H. Chen, M. C. Warnock, M. R. Gyetko, R. A. McDonald, P. H. Scott, and G. T. Toews. 1994. Experimental murine pulmonary cryptococcosis. Differences in pulmonary inflammation and lymphocyte recruitment induced by two encapsulated strains of Cryptococcus neufomans. Lab. Invest. 71:115-126.
    • (1994) Lab. Invest. , vol.71 , pp. 115-126
    • Curtis, J.L.1    Huffhagle, G.B.2    Chen, G.H.3    Warnock, M.C.4    Gyetko, M.R.5    McDonald, R.A.6    Scott, P.H.7    Toews, G.T.8
  • 14
    • 0027400726 scopus 로고
    • Multiple defects of immune cell function in mice with disrupted Interferon gamma genes
    • Dalton, D. K., S. Pitts-Miik, S. Keshav, I. S. Figari, A. Bradley, and T. A. Stewart. 1993. Multiple defects of immune cell function in mice with disrupted Interferon gamma genes. Science 259:1739-1742.
    • (1993) Science , vol.259 , pp. 1739-1742
    • Dalton, D.K.1    Pitts-Miik, S.2    Keshav, S.3    Figari, I.S.4    Bradley, A.5    Stewart, T.A.6
  • 15
    • 0029004042 scopus 로고
    • Lgn-1 a gene that determines susceptibility to Legianella pneumophila maps to mouse chromosome 13
    • Dietrich, W. F., D. M. Damron. R. R. Isberg, E. S. Lander, and M. S. Swanson. 1995. Lgn-1 a gene that determines susceptibility to Legianella pneumophila maps to mouse chromosome 13. Genomics 26:443-450.
    • (1995) Genomics , vol.26 , pp. 443-450
    • Dietrich, W.F.1    Damron, D.M.2    Isberg, R.R.3    Lander, E.S.4    Swanson, M.S.5
  • 16
    • 0019409995 scopus 로고
    • Improved semiselective medium for isolation of Legionella pneumophila from contaminated clinical and environmental specimens
    • Edelstein, P. H. 1981. Improved semiselective medium for isolation of Legionella pneumophila from contaminated clinical and environmental specimens. J. Clin. Microbiol. 14:298-303.
    • (1981) J. Clin. Microbiol. , vol.14 , pp. 298-303
    • Edelstein, P.H.1
  • 18
    • 0026846833 scopus 로고
    • Investigation of the role of macrophages and endogenous IFN-γ in natural resistance of mice against Legionella pneumophila infections
    • Fujio, H., S. Yoshidu, M. Mitsuyana, and Y. Mizuguchi. 1992. Investigation of the role of macrophages and endogenous IFN-γ in natural resistance of mice against Legionella pneumophila infections. FEMS Microbiol. Immunol. 89:183-192.
    • (1992) FEMS Microbiol. Immunol. , vol.89 , pp. 183-192
    • Fujio, H.1    Yoshidu, S.2    Mitsuyana, M.3    Mizuguchi, Y.4
  • 19
    • 0028048245 scopus 로고
    • Inhibition of Legionella pneumophila growth by gamma interferon in permissive A/J mouse macrophages: Role of reactive oxygen species, nitric oxide, tryptophan, and iron(III)
    • Gebran, S. J., Y. Yamamoto, C. Newton, T. Klein, and H. Friedman. 1994. Inhibition of Legionella pneumophila growth by gamma interferon in permissive A/J mouse macrophages: role of reactive oxygen species, nitric oxide, tryptophan, and iron(III). Infect. Immun, 62:3197-3205.
    • (1994) Infect. Immun , vol.62 , pp. 3197-3205
    • Gebran, S.J.1    Yamamoto, Y.2    Newton, C.3    Klein, T.4    Friedman, H.5
  • 20
    • 0028893459 scopus 로고
    • LPS inhibits the intracellular growth of Legionella pneumophila in thioglycolate elicited murine peritoneal macrophages by an iron-dependent, tryptophan independent, oxygen independent and arginine independent mechanism
    • Gebran, S. J., Y. Yamamoto, C. Newton, M. Tomiaka, R. Widen, T. W. Klein, and H. Friedman. 1995. LPS inhibits the intracellular growth of Legionella pneumophila in thioglycolate elicited murine peritoneal macrophages by an iron-dependent, tryptophan independent, oxygen independent and arginine independent mechanism. J. Leukocyte Biol. 57:80-87.
    • (1995) J. Leukocyte Biol. , vol.57 , pp. 80-87
    • Gebran, S.J.1    Yamamoto, Y.2    Newton, C.3    Tomiaka, M.4    Widen, R.5    Klein, T.W.6    Friedman, H.7
  • 21
    • 0025017079 scopus 로고
    • Metabolite fact of I.-arginine in relation to microbiostatic capabilities of murine macrophages
    • Granger, D. L., J. B. Hibbs, Jr., J. R. Perfect, and D. T. Durack. 1990. Metabolite fact of I.-arginine in relation to microbiostatic capabilities of murine macrophages. J. Clin. Invest. 85:264-273.
    • (1990) J. Clin. Invest. , vol.85 , pp. 264-273
    • Granger, D.L.1    Hibbs Jr., J.B.2    Perfect, J.R.3    Durack, D.T.4
  • 22
    • 0025791009 scopus 로고
    • Cytokine induced synthesis of nitrogen-oxides in macrophages: A protective host response to Leishmania and other intracellular pathogens
    • Green, S. J., C. A. Nacy, and M. S. Meltzer. 1990. Cytokine induced synthesis of nitrogen-oxides in macrophages: a protective host response to Leishmania and other intracellular pathogens. J. Leukocyte Biol. 50:93-103.
    • (1990) J. Leukocyte Biol. , vol.50 , pp. 93-103
    • Green, S.J.1    Nacy, C.A.2    Meltzer, M.S.3
  • 23
    • 0021014278 scopus 로고
    • The Legionnaires' disease bacterium (Leffonella pneumophila) inhibits phagosome-lysosome fusion in human monocytes
    • Horwitz, M. A. 1983. The Legionnaires' disease bacterium (Leffonella pneumophila) inhibits phagosome-lysosome fusion in human monocytes. J. Exp. Med. 158:2108-2126.
    • (1983) J. Exp. Med. , vol.158 , pp. 2108-2126
    • Horwitz, M.A.1
  • 24
    • 0021346850 scopus 로고
    • Phagocytosis of Legionnaires' disease bacterium (Legionella pneumophila) occurs by a novel mechanism: Engulfment within a pseudopod coil
    • Horwitz, M. A. 1984. Phagocytosis of Legionnaires' disease bacterium (Legionella pneumophila) occurs by a novel mechanism: engulfment within a pseudopod coil. Cell 36:27-33.
    • (1984) Cell , vol.36 , pp. 27-33
    • Horwitz, M.A.1
  • 25
    • 0018885613 scopus 로고
    • The Legionnaires' disease bacterium (Legionella pneumophila) multiples intracellularly in human monocytes
    • Horwitz, M. A., and S. C. Silverstein. 1980. The Legionnaires' disease bacterium (Legionella pneumophila) multiples intracellularly in human monocytes. J. Clin. Invest. 66:441-450.
    • (1980) J. Clin. Invest. , vol.66 , pp. 441-450
    • Horwitz, M.A.1    Silverstein, S.C.2
  • 26
    • 0019850890 scopus 로고
    • Activated human monocytes inhibit the intracellular multiplication of Legionnaires' disease bacteria
    • Horwitz, M. A., and S. C. Silverstein. 1981. Activated human monocytes inhibit the intracellular multiplication of Legionnaires' disease bacteria. J. Exp. Med. 154:1618-1635.
    • (1981) J. Exp. Med. , vol.154 , pp. 1618-1635
    • Horwitz, M.A.1    Silverstein, S.C.2
  • 27
    • 0028053270 scopus 로고
    • The role of CD4+ and CD8+ T cells in the protective inflammatory response to pulmonary cryptococcal infection
    • Huffnagle, G. B., M. F. Llpscomb, J. A. Lovchik, K. A. Hoag, and N. E. Street. 1994. The role of CD4+ and CD8+ T cells in the protective inflammatory response to pulmonary cryptococcal infection. J. Leukocyte Biol. 55:35-42.
    • (1994) J. Leukocyte Biol. , vol.55 , pp. 35-42
    • Huffnagle, G.B.1    Llpscomb, M.F.2    Lovchik, J.A.3    Hoag, K.A.4    Street, N.E.5
  • 28
    • 0023112361 scopus 로고
    • In vitro activation of the antibacterial activity of human pulmonary macrophage by recombinant gamma Interferon
    • Jenson, W. A., R. M. Rose, A. S. Washerman, T. H. Kalb, K. Anton, and J. G. Remold. 1987. In vitro activation of the antibacterial activity of human pulmonary macrophage by recombinant gamma Interferon. J. Infect. Dis. 155:574-577.
    • (1987) J. Infect. Dis. , vol.155 , pp. 574-577
    • Jenson, W.A.1    Rose, R.M.2    Washerman, A.S.3    Kalb, T.H.4    Anton, K.5    Remold, J.G.6
  • 29
    • 0014949207 scopus 로고
    • Cleavage of structural proteins during the assembly of the head of bacteriophage T4
    • Laemmli, U. K. 1970. Cleavage of structural proteins during the assembly of the head of bacteriophage T4. Nature (London) 227:680-685.
    • (1970) Nature (London) , vol.227 , pp. 680-685
    • Laemmli, U.K.1
  • 30
    • 0025117611 scopus 로고
    • EPR demonstration of iron nitrosyl complex formation by cytokine activated macrophages
    • Lancaster, J. R., and J. B. Hibbs, Jr. 1990. EPR demonstration of iron nitrosyl complex formation by cytokine activated macrophages. Proc. Natl. Acad. Sci. USA 87:1223-1227.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 1223-1227
    • Lancaster, J.R.1    Hibbs Jr., J.B.2
  • 31
    • 0027190721 scopus 로고
    • Activation of human peripheral blood mononucleur cells by nitric oxide-generating compounds
    • Lander, H. M., P. Z. Sehajpal, D. M. Levine, and A. Novogrodsky. 1993. Activation of human peripheral blood mononucleur cells by nitric oxide-generating compounds. J. Immunol. 150:1509-1516.
    • (1993) J. Immunol. , vol.150 , pp. 1509-1516
    • Lander, H.M.1    Sehajpal, P.Z.2    Levine, D.M.3    Novogrodsky, A.4
  • 32
    • 0027429403 scopus 로고
    • Involvement of tumor necrosis factor alpha in intracellular multiplication of Legionella pneumophila in human monocytes
    • Matsiota-Bernard, P., C. Léfèbre, M. Sedqul, P. Cornillet, and M. Guenounou. 1993. Involvement of tumor necrosis factor alpha in intracellular multiplication of Legionella pneumophila in human monocytes. Infect. Immun. 61:4980-4983.
    • (1993) Infect. Immun. , vol.61 , pp. 4980-4983
    • Matsiota-Bernard, P.1    Léfèbre, C.2    Sedqul, M.3    Cornillet, P.4    Guenounou, M.5
  • 33
    • 0026652811 scopus 로고
    • Immune complex induced lung and dermal vascular injury. Differing requirements for tumor necrosis factor alpha and IL-1
    • Mulligan, M. S., and P. A. Ward. 1992. Immune complex induced lung and dermal vascular injury. Differing requirements for tumor necrosis factor alpha and IL-1. J. Immunol. 19:331-339.
    • (1992) J. Immunol. , vol.19 , pp. 331-339
    • Mulligan, M.S.1    Ward, P.A.2
  • 34
    • 0023875737 scopus 로고
    • IFN-γ activated human alveolar macrophages inhibit the intracellular multiplication of Legionella pneumophila
    • Nash, T. W., D. M. Libby, and M. A. Horwitz. 1988. IFN-γ activated human alveolar macrophages inhibit the intracellular multiplication of Legionella pneumophila. J. Immunol. 140:3978-3981.
    • (1988) J. Immunol. , vol.140 , pp. 3978-3981
    • Nash, T.W.1    Libby, D.M.2    Horwitz, M.A.3
  • 35
    • 0025695636 scopus 로고
    • Nitric oxide mediates iron release from ferritin
    • Reif, D. W., and R. D. Simmons. 1990. Nitric oxide mediates iron release from ferritin. Arch. Biochem. Biophys. 283:537-541.
    • (1990) Arch. Biochem. Biophys. , vol.283 , pp. 537-541
    • Reif, D.W.1    Simmons, R.D.2
  • 36
    • 0027753289 scopus 로고
    • Requirement for neutrophil products and I.-arginine in ischemia reperfusion injury
    • Seekamp, A., M. S. Mulligan, G. O. Till, and P. A. Ward. 1993. Requirement for neutrophil products and I.-arginine in ischemia reperfusion injury. Am. J. Pathol. 142:1217-1226.
    • (1993) Am. J. Pathol. , vol.142 , pp. 1217-1226
    • Seekamp, A.1    Mulligan, M.S.2    Till, G.O.3    Ward, P.A.4
  • 37
    • 0022597420 scopus 로고
    • Binding of Griffonia simplicifolia I Icelin to rat pulmonary alveolar macrophages and its use in purifying type II alveolar epithelial cells
    • Simon, R. H., J. P. McCoy, A. E. Chu, P. D. Dehart, and I. J. Goldstein. 1986. Binding of Griffonia simplicifolia I Icelin to rat pulmonary alveolar macrophages and its use in purifying type II alveolar epithelial cells. Biochim. Biophys. Acta. 885:34-42.
    • (1986) Biochim. Biophys. Acta. , vol.885 , pp. 34-42
    • Simon, R.H.1    McCoy, J.P.2    Chu, A.E.3    Dehart, P.D.4    Goldstein, I.J.5
  • 38
    • 0026478554 scopus 로고
    • Rccombinant murine Interferon-γ reversibly activates rat alveolar macrophages to kill Legionella pneumophila
    • Skerrett, S. J., and T. R. Martin. 1992. Rccombinant murine Interferon-γ reversibly activates rat alveolar macrophages to kill Legionella pneumophila. J. Infect. Dis. 166:1354-1361.
    • (1992) J. Infect. Dis. , vol.166 , pp. 1354-1361
    • Skerrett, S.J.1    Martin, T.R.2
  • 39
    • 0028178096 scopus 로고
    • Intratrachcal interferon-γ augments pulmonary defenses in experimental legionellosis
    • Skerrett, S. J., and T. R. Martin. 1994. Intratrachcal interferon-γ augments pulmonary defenses in experimental legionellosis. Am. J. Respir. Crit. Care Med. 149:50-58.
    • (1994) Am. J. Respir. Crit. Care Med. , vol.149 , pp. 50-58
    • Skerrett, S.J.1    Martin, T.R.2
  • 40
    • 0024390511 scopus 로고
    • Impaired clearance of aerosolized Legionella pneumophila in corticosteroid-treated rats: A model of Legionnaires' disease in the compromised host
    • Skerrett, S. J., R. A. Schmidt, and T. R. Martin. 1989. Impaired clearance of aerosolized Legionella pneumophila in corticosteroid-treated rats: a model of Legionnaires' disease in the compromised host. J. Infect. Dis. 160:261-275.
    • (1989) J. Infect. Dis. , vol.160 , pp. 261-275
    • Skerrett, S.J.1    Schmidt, R.A.2    Martin, T.R.3
  • 41
    • 0022641486 scopus 로고
    • In vivo treatment of mice and hamsters with antibodies to asiolo GM1 increases morbidity and mortality to pulmonary influenza infection
    • Stein-Strellein, J., and J. Guffee. 1986. In vivo treatment of mice and hamsters with antibodies to asiolo GM1 increases morbidity and mortality to pulmonary influenza infection. J. Immunol. 136:1436-1441.
    • (1986) J. Immunol. , vol.136 , pp. 1436-1441
    • Stein-Strellein, J.1    Guffee, J.2
  • 42
    • 0027078640 scopus 로고
    • Killing of Legionella pneumophila by nitric oxide in γ-interferon activated macrophages
    • Summersgill, J. T., L. A. Powell, B. L. Buster, R. D. Miller, and J. A. Ramirez. 1992. Killing of Legionella pneumophila by nitric oxide in γ-interferon activated macrophages. J. Leukocyte Biol. 52:625-629.
    • (1992) J. Leukocyte Biol. , vol.52 , pp. 625-629
    • Summersgill, J.T.1    Powell, L.A.2    Buster, B.L.3    Miller, R.D.4    Ramirez, J.A.5
  • 45
    • 0027953936 scopus 로고
    • Nitric oxide has an immunoregulatory role other than antimicrobial activity in Legionella pneumophila infected macrophages
    • Yamamoto, Y., H. Friedman, and T. W. Klein. 1994. Nitric oxide has an immunoregulatory role other than antimicrobial activity in Legionella pneumophila infected macrophages. Ann. N. Y. Acad. Sci. 730:342-344.
    • (1994) Ann. N. Y. Acad. Sci. , vol.730 , pp. 342-344
    • Yamamoto, Y.1    Friedman, H.2    Klein, T.W.3
  • 46
    • 0023220888 scopus 로고
    • Differential growth of Legionella pneumophila in guinea pigs versus mouse macrophage cultures
    • Yamamoto, Y., T. W. Klein, C. A. Newton, R. Widen, and H. Friedman. 1987. Differential growth of Legionella pneumophila in guinea pigs versus mouse macrophage cultures. Infect, Immun. 55:1369-1374.
    • (1987) Infect, Immun. , vol.55 , pp. 1369-1374
    • Yamamoto, Y.1    Klein, T.W.2    Newton, C.A.3    Widen, R.4    Friedman, H.5
  • 47
    • 0022637489 scopus 로고
    • Multiplication of Legiunella pneumophila Philadelphia-1 in cultured peritoneal macrophages and its correlation to susceptibility of animals
    • Yoshida, S., and Y. Mizuguch. 1986. Multiplication of Legiunella pneumophila Philadelphia-1 in cultured peritoneal macrophages and its correlation to susceptibility of animals. Can. J. Microbiol. 32:438-442.
    • (1986) Can. J. Microbiol. , vol.32 , pp. 438-442
    • Yoshida, S.1    Mizuguch, Y.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.