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Volumn 10, Issue 2, 2002, Pages 291-302

Conformationally restricted TRH analogues: Constraining the pyroglutamate region

Author keywords

[No Author keywords available]

Indexed keywords

LACTAM; PROTIRELIN; PROTIRELIN DERIVATIVE; PYROGLUTAMIC ACID;

EID: 0036132390     PISSN: 09680896     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0968-0896(01)00287-5     Document Type: Article
Times cited : (23)

References (37)
  • 5
    • 0006809132 scopus 로고    scopus 로고
    • (a)For reviews on the biology of TRH, see: Thyrotropin-Releasing Hormone: Biomedical Significance; In Metcalf Olson, G. L.; Cheung, H. C.; Voss, M. E.; Hill, D. E.; Kahn, M.; Madison, V. S.; Cook, C. M.; Sepinwall, J, Eds. Proceedings of the Biotech USA 89Meeting 1989, San Francisco, October 1989.
  • 7
    • 0006844859 scopus 로고    scopus 로고
    • (a)For work leading to 1 as a proposed endocrine receptor bound conformation of TRH, see: Marshall, G. R.; Gorin, F. A.; Moore, M. L. In Annual Reports in Medicinal Chemistry; Clarke, F. H., Ed.; Academic: New York, 1978; Vol. 13, p 227, and references therein.
  • 8
    • 0006810766 scopus 로고    scopus 로고
    • (b)Font, J. PhD Thesis, Washington University in St. Louis, 1986.
  • 25
    • 0006818006 scopus 로고    scopus 로고
    • 1 have shown that the fully constrained analogue (n=m=1) is a full agonist of the receptor. Gershengorn, M. C.; Chu, W.; Moeller, K. D. Unpublished results.
  • 26
    • 0006848968 scopus 로고    scopus 로고
    • (a)For reviews of anodic amide oxidations, see: Shono, T.; Matsumura, Y.; Tsubata, K. In Organic Synthesis; Saucy, G., Ed.; Organic Synthesis, 1984, Vol. 63, p 206, and references therein.
  • 27
    • 0006840069 scopus 로고    scopus 로고
    • (b)Shono, T. In Topics in Current Chemistry; Steckhan, E., Ed.; Springer: Berlin, 1988; Vol. 148, p 131.
  • 28
    • 0002330654 scopus 로고    scopus 로고
    • For applications to functionalizing amino acids, see:, and in particular reference 13 therein
    • (1997) Top. Curr. Chem. , vol.185 , pp. 49
    • Moeller, K.D.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.