Involvement of FAK, P13-K and PKC in cell adhesion induced by microtubule disruption;Implication de la FAK, de la P13-K et des PKC dans l'adhésion induite par la dépolymérisation des microtubules

Bulletin du Cancer

Volumn 89, Issue 2, 2002, Pages 227-233

  Kadi, Azzeddine ^a   Berthet, Virginie ^a   Pichard, Véronique ^a   Abadie, Brigitte ^a   Rognoni, Jean Baptiste ^a   Marvaldi, Jacques ^a   Luis, José ^a  

^a AIX MARSEILLE UNIVERSITY   (France)

Author keywords

Adhesion; Cytoskelete; Integrin; Nocodazole; Vinorelbine

Indexed keywords

DOCETAXEL; FOCAL ADHESION KINASE; INTEGRIN; NAVELBINE; NOCODAZOLE; PACLITAXEL; PAXILLINE; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHATIDYLINOSITOL 3 KINASE INHIBITOR; PROTEIN KINASE C; PROTEIN KINASE C INHIBITOR; PROTEIN TYROSINE KINASE INHIBITOR;

ARTICLE; BINDING AFFINITY; CELL ADHESION; CELLULAR DISTRIBUTION; CONTROLLED STUDY; CYTOSKELETON; ENZYME ANALYSIS; HUMAN; HUMAN CELL; MICROTUBULE ASSEMBLY; PROTEIN PHOSPHORYLATION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANTINEOPLASTIC AGENTS; CELL ADHESION; FOCAL ADHESION KINASE 2; HT29 CELLS; HUMANS; MICROTUBULES; NOCODAZOLE; PACLITAXEL; PROTEIN KINASE C; PROTEIN-TYROSINE KINASES; VINBLASTINE;

EID: 0036130764     PISSN: 00074551     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (31)

1. The hallmarks of cancer
2. Integrin structure
3. Integrin signaling
4. Cell adhesion: The molecular basis of tissue architecture and morphogenesis
5. Where the outside meets the inside: Integrins as activators and targets of signal transduction cascades
6. Chimiothérapie du cancer du sein métastatique
7. Vinorelbine: A clinical review
8. Preclinical evaluation of docetaxel (Taxotere)
9. Phase I and pharmacokinetic study of docetaxel and irinotecan in patients with advanced solid tumors
10. Cytoskeletal filament assembly and the control of cell spreading and function by extracellular matrix
11. Involvement of microtubules in the control of adhesion-dependent signal transduction
12. Effect of microtubule disruption on cell adhesion and spreading
13. The bisindolylmaleimide GF 109203X is a potent and selective inhibitor of protein kinase C
14. Chelerythrine is a potent and specific inhibitor of protein kinase C
15. Protein kinases C-γ and -δ are involved in insulin-like growth factor I-induced migration of colonic epithelial cells
16. Effect of colcemid on the spreading of fibroblasts in culture
17. Effect of microtubule-destroying drugs on the spreading and shape of cultured epithelial cells
18. Microtubule disruption induces the formation of actin stress fibers and focal adhesion in cultured cells: Possible involvement of the Rho signal cascade
19. Fibroblast contractibility and actin organization are stimulated by microtubule inhibitors
20. Contraction due to microtubule disruption is associated with increased phosphorylation of myosin regulatory light chain
21. Rho-stimulated contractility drives the formation of stress fibers and focal adhesions
22. Changes in fibroblast contractility, morphology, and adhesion in response to a phorbol ester tumor promoter
23. Integrin ligation and PKC activation are required for migration of colon carcinoma cells
24. Microtubule depolymerization induces stress fibers, focal adhesions, and DNA synthesis via the GTP-binding protein Rho
25. Focal adhesions: A nexus for intracellular signaling and cytoskeletal dynamics
26. Integrin-mediated muscle cell spreading. The role of protein kinase c in outside-in and inside-out signaling and evidence of integrin cross-talk
27. Requirement for diacylglycerol and protein kinase C in HeLa cell-substratum adhesion and their feedback amplification of arachidonic acid production for optimum cell spreading
28. Signal transduction and signal modulation by cell adhesion receptors: The role of integrins, cadherins, immunoglobulin-cell adhesion molecules, and selectins
29. Platelet-derived growth factor activates protein kinase C epsilon through redundant and independent signaling pathways involving phospholipase C gamma or phosphatidylinositol 3-kinase
30. Activation of protein kinase C family members by the novel polyphosphoinositides PtdIns-3,4-P2 and PtdIns-3,4,5-P3
31. Spontaneous and induced dome formation by two clonal cell populations derived from a human adenocarcinoma cell line HT29