Mammary cancer and epithelial stem cells: A problem or a solution?

Breast Cancer Research

Volumn 4, Issue 2, 2002, Pages 47-50

  Smith, Gilbert H ^a  

^a NATIONAL CANCER INSTITUTE   (United States)

Author keywords

Aging; Mammary; Neoplasia; Stem cell; Transplantation

Indexed keywords

AGE; ANIMAL CELL; ARTICLE; BONE MARROW; BREAST CANCER; CANCER PREVENTION; CANCER THERAPY; CONTROLLED STUDY; DIGESTIVE SYSTEM; EPITHELIUM CELL; FEMALE; INTEGUMENT; LIFESPAN; LIVER; LUNG; MOUSE; NONHUMAN; REGENERATION; REPRODUCTION; SKELETAL MUSCLE; STEM CELL;

ANIMALS; BREAST; CELL AGING; CELL DIVISION; DOGS; EPITHELIAL CELLS; EPITHELIUM; FEMALE; MAMMARY NEOPLASMS, ANIMAL; MICE; MICROSATELLITE REPEATS; PHENOTYPE; RATS; RISK; STEM CELLS;

EID: 0036126256     PISSN: 14655411     EISSN: None     Source Type: Journal    
DOI: 10.1186/bcr420     Document Type: Article

References (26)

1. Contiguous patches of normal human epithelium derived from a single stem cell: Implications for breast carcinogenesis
2. Phenotypic and functional characterization in vitro of a multipotent epithelial cell present in the normal adult human breast
3. Human mammary luminal epithelial cells contain progenitors to myoepithelial cells
4. Characterization of bipotent mammary epithelial progenitor cells in normal adult human breast tissue
5. Loss of heterozygosity in normal tissue adjacent to breast carcinomas
6. Detection of allelic imbalance indicates that a proportion of mammary hyperplasia of usual type are clonal, neoplastic proliferations
7. Genetic alterations in 'normal' luminal and myoepithelial cells of the breast
8. Expression of different phenotypes in cell lines from canine mammary spindle-cell tumours and osteosarcomas indicating a pluripotent mammary stem cell origin
9. Quantitative studies of ductal versus alveolar differentiation from rat mammary clonogens
10. Kinetics of mammary clonogenic cells and rat mammary cancer induction by X-rays or fission neutrons
11. Stem cell characteristics of transplanted rat mammary clonogens
12. An entire functional mammary gland may comprise the progeny from a single cell
13. Somatic control over the germline stem cell lineage during Drosophila spermatogenesis
14. A niche maintaining germ line stem cells in the Drosophila ovary
15. Stimulation of human epidermal differentiation by delta-notch signalling at the boundaries of stem-cell clusters
16. c-Myc activation in transgenic mouse epidermis results in mobilization of stem cells and differentiation of their progeny
17. Constitutive expression of a truncated INT3 gene in mouse mammary epithelium impairs differentiation and functional development
18. Mammary epithelial stem cells
19. Influence of cell division on an aging process. Life span of mouse mammary epithelium during serial propagation in vivo
20. The in vivo life span of normal and preneoplastic mouse mammary glands: A serial transplantation study
21. The influence of host and tissue age on life span and growth rate of serially transplanted mouse mammary gland
22. A morphologically distinct candidate for an epithelial stem cell in mouse mammary gland
23. Three division-competent, structurally-distinct cell populations contribute to murine mammary epithelial renewal
24. Microsatellite alterations indicating monoclonality in atypical hyperplasias associated with breast cancer
25. Reducing mammary cancer risk through premature stem cell senescence
26. An adjunct mammary epithelial cell population in parous females: Its role in functional adaptation and tissue renewal