Accumulation of biglycan and perlecan, but not versican, in lesions of murine models of atherosclerosis

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 22, Issue 3, 2002, Pages 462-468

  Kunjathoor, Vidya V ^a   Chiu, Diane S ^a   O'Brien, Kevin D ^a   LeBoeuf, Renée C ^a  

^a UNIVERSITY OF WASHINGTON   (United States)

Author keywords

ApoE deficiency; Apolipoproteins; Atherosclerosis; LDL receptor deficiency; Proteoglycans

Indexed keywords

APOLIPOPROTEIN A1; APOLIPOPROTEIN B; APOLIPOPROTEIN E; BIGLYCAN; LOW DENSITY LIPOPROTEIN RECEPTOR; PERLECAN; PROTEOGLYCAN; VERSICAN;

ANIMAL MODEL; ANIMAL TISSUE; ARTERY INTIMA; ARTICLE; ATHEROGENESIS; ATHEROSCLEROSIS; ATHEROSCLEROTIC PLAQUE; DISEASE COURSE; FEMALE; HYPERLIPOPROTEINEMIA TYPE 3; MALE; MOUSE; NONHUMAN; PRIORITY JOURNAL;

ANIMALS; AORTIC DISEASES; APOLIPOPROTEINS; APOLIPOPROTEINS E; ARTERIOSCLEROSIS; DISEASE PROGRESSION; EXTRACELLULAR MATRIX PROTEINS; FEMALE; HEPARAN SULFATE PROTEOGLYCANS; LECTINS, C-TYPE; MALE; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; PROTEOCHONDROITIN SULFATES; PROTEOGLYCANS; RECEPTORS, LDL; SINUS OF VALSALVA; TUNICA MEDIA; VERSICANS;

EID: 0036124554     PISSN: 10795642     EISSN: None     Source Type: Journal    
DOI: 10.1161/hq0302.105378     Document Type: Article

References (40)

1. The response-to-retention hypothesis of early atherogenesis
2. Cellular consequences of the association of apoB lipoproteins with proteoglycans: Potential contribution to atherogenesis
3. The glycosaminoglycans of the human artery and their changes in atherosclerosis
4. Acidic glycosaminoglycans in human atherosclerotic cerebral arterial tissues
5. Distribution of glycosaminoglycans in the intimal of human aortas: Changes in atherosclerosis and diabetes mellitus
6. Dynamics of lipoprotein-glycosaminoglycan interactions in the atherosclerotic rabbit aorta in vivo
7. Proteoglycan distribution in lesions of atherosclerosis depends on lesion severity, structural characteristics, and the proximity of platelet-derived growth factor and transforming growth factor-beta
8. Selective deposits of versican in the extracellular matrix of restenotic lesions from human peripheral arteries
9. Comparison of apolipoprotein and proteoglycan deposits in human coronary atherosclerotic plaques: Colocalization of biglycan with apolipoproteins
10. Matrix proteoglycans: From molecular design to cellular function
11. Spontaneous hypercholesterolemia and arterial lesions in mice lacking apolipoprotein E
12. Massive xanthomatosis and atherosclerosis in cholesterol-fed low density lipoprotein receptor-negative mice
13. ApoE-deficient mice develop lesions of all phases of atherosclerosis throughout the arterial tree
14. Western-type diets induce insulin resistance and hyperlinsulinemia in LDL receptor-deficient mice but do not increase aortic atherosclerosis compared with normoinsulinemic mice in which similar plasma cholesterol levels are achieved by a fructose-rich diet
15. Increased atherosclerosis in streptozotocin-induced diabetic mice
16. Characterization of proteoglycans synthesized by murine embryonal carcinoma cells (P19) reveals increased expression of perlecan (heparan sulfate proteoglycan) during neuronal differentiation
17. Apolipoproteins B, (a), and E accumulation in the morphologically early lesion of "degenerative" valvular aortic stenosis
18. Synthetic amphipathic helical peptides that mimic apolipoprotein A-I in clearing cellular cholesterol
19. Lipoprotein lipase is synthesized by macrophage-derived foam cells in human coronary atherosclerotic plaques
20. Impaired superoxide production due to a deficiency in phagocyte NADPH oxidase fails to inhibit atherosclerosis in mice
21. A definition of advanced types of atherosclerotic lesions and a histological classification of atherosclerosis: A report from the Committee on Vascular Lesions of the Council on Arteriosclerosis, American Heart Association
22. Peripheral vascular stenosis in apolipoprotein E-deficient mice: Potential roles of lipid deposition, medial atrophy, and adventitial inflammation
23. Perlecan, basal lamina proteoglycan, promotes basic fibroblast growth factor-receptor binding, mitogenesis, and angiogenesis
24. Perlecan mediates the antiproliferative effect of apolipoprotein E on smooth muscle cells: An underlying mechanism for the modulation of smooth muscle growth?
25. Perlecan is required to inhibit thrombosis after deep vascular injury and contributes to endothelial cell-mediated inhibition of intimal hyperplasia
26. Biglycan, a vascular proteoglycan, binds differently to HDL2 and HDL3: Role of apoE
27. Interaction of biglycan with type I collagen
28. Phospholipase A2 type II binds to extracellular matrix biglycan: Modulation of its activity on LDL by colocalization in glycosaminoglycan matrixes
29. Proteoglycan composition of rabbit arterial wall under conditions of experimentally induced atherosclerosis
30. Plasma low density lipoprotein accumulation in aortas of hypercholesterolemic swine correlates with modifications in aortic glycosaminoglycan composition
31. Immunolocalization of proteoglycan types in aortas of pigeons with spontaneous or dietinduced atherosclerosis
32. Human abdominal aortic aneurysm is characterized by decreased versican concentration and specific downregulation of versican isoform V(0)
33. A definition of initial, fatty streak, and intermediate lesions of arteriosclerosis: A report from the committee on vascular lesions of the Council on Arteriosclerosis, American Heart Association
34. Initiation of atherosclerotic lesions in cholesterol-fed rabbits, I: Focal increases in arterial LDL concentration precede development of fatty streak lesions
35. Macrophage expression of human apolipoprotein E reduces atherosclerosis in hypercholesterolemic apolipoprotein E-null mice
36. Effect of bone marrow transplantation on lipoprotein metabolism and atherosclerosis in LDL receptor-knockout mice
37. Apolipoprotein E-dependent cholesterol efflux from macrophages: Kinetic study and divergent mechanisms for endogenous versus exogenous apolipoprotein E
38. Altered immune responses in apolipoprotein E-deficient mice
39. Abundant expression of apoprotein E by macrophages in human and rabbit atherosclerotic lesions
40. Increased atherosclerosis in mice reconstituted with apolipoprotein E null macrophages