Expression of the multidrug resistance-associated protein (mrp) gene in chronic lymphocytic leukemia

Leukemia and Lymphoma

Volumn 43, Issue 1, 2002, Pages 153-158

  Juszczynski, Przemys ^a   Niewiarowski, Wojciech ^b   Krykowski, Euzebiusz ^a   Robak, Tadeusz ^a   Warzocha, Krzysztof ^a  

^a MEDICAL UNIVERSITY OF LODZ   (Poland)

^b CENTRE OF MOLECULAR AND MACROMOLECULAR STUDIES   (Poland)

Author keywords

Chronic lymphocytic leukemia; Drug resistance

Indexed keywords

ALKYLATING AGENT; ANTILEUKEMIC AGENT; ANTINEOPLASTIC AGENT; CHLORAMBUCIL; CLADRIBINE; CORTICOSTEROID; CYCLOPHOSPHAMIDE; DNA; DOXORUBICIN; MULTIDRUG RESISTANCE PROTEIN; PREDNISONE; PURINE DERIVATIVE; VINCRISTINE; MESSENGER RNA;

ADULT; ADVANCED CANCER; AGED; ARTICLE; BLOOD DONOR; CANCER CHEMOTHERAPY; CANCER GROWTH; CELL ISOLATION; CHRONIC LYMPHATIC LEUKEMIA; CLINICAL ARTICLE; CONTROLLED STUDY; FEMALE; GENE AMPLIFICATION; GENE EXPRESSION; GENE TARGETING; GENETIC TRANSCRIPTION; HUMAN; HUMAN CELL; LABORATORY TEST; LEUKOCYTE; LYMPHOCYTE COUNT; MALE; MEDICAL PARAMETERS; PATHOGENESIS; PERIPHERAL LYMPHOCYTE; PHENOTYPE; PRIORITY JOURNAL; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; SALVAGE THERAPY; SEQUENCE HOMOLOGY; STANDARD; CASE CONTROL STUDY; DISEASE COURSE; GENETICS; LEUKOCYTOSIS; LYMPHOCYTE; METABOLISM; MIDDLE AGED; PATHOLOGY;

ADULT; AGED; AGED, 80 AND OVER; CASE-CONTROL STUDIES; DISEASE PROGRESSION; FEMALE; HUMANS; LEUKEMIA, LYMPHOCYTIC, CHRONIC; LEUKOCYTOSIS; LYMPHOCYTES; MALE; MIDDLE AGED; MULTIDRUG RESISTANCE-ASSOCIATED PROTEINS; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER;

EID: 0036118251     PISSN: 10428194     EISSN: None     Source Type: Journal    
DOI: 10.1080/10428190210198     Document Type: Article

References (37)

1. "Mechanism of drug resistance in hematological malignancies"
2. "Is the mdr I gene relevant in chronic lymphocytic leukemia?"
3. "The expression of the multidrug resistance-associated glycoprotein in B-cell chronic lymphocytic leukaemia"
4. "Drug resistance mechanisms in chronic lymphocytic leukemia"
5. "High expression of the mdr3 multidrug-resistance gene in advanced-stage chronic lymphocytic leukemia"
6. "MDR1 gene expression in chronic lymphocytic leukaemia"
7. "Overexpression of a transporter gene in a multidrug-resistant human lung cancer cell line"
8. "Gene associated with a non-P-glycoprotein multidrug resistance encodes a 190 kDa membrane bound glycoprotein"
9. "A 190 kilodalton protein overexpressed in non-P-glycoprotein-containing multidrug resistant cells and its relationship to MRP gene"
10. "Localization of a novel multidrug resistance-associated gene in the HT1080/DR4 and H69AR human tumor cell lines"
11. "Analysis of the expression of MRP, the gene coding for a new putative transmembrane drug efflux transporter, in human multidrug resistant lung cancer cell lines"
12. "Analysis of MRP mRNA in mitoxantrone-selected, multidrug-resistant human tumor cells"
13. "Multidrug resistance-associated protein gene over-expression and reduced drug sensitivity of topoisomerase II in a human breast carcinoma MCF7 cell line selected for etoposide resistance"
14. "Overexpression of multidrug resistance-associated protein (MRP) increases resistance to natural product drugs"
15. "Expression complementary DNA library transfer establishes mrp as a multidrug resistance gene"
16. "Double knockout of the MRP gene leads to increased drug sensitivity in vitro"
17. "Increased expression of the multidrug resistance associated protein gene in relapsed acute leukemia"
18. "High expression of the multidrug resistance-associated protein (MRP) in chronic and prolymphocytic leukaemia"
19. "Expression of the multidrug resistance-associated protein (MRP) in acute and chronic leukemias"
20. "Expression of the multidrug resistance-associated protein (MRP) in acute leukaemia"
21. "Frequency and clinical significance of the expression of the multidrug resistance proteins MDR1/P-glycoprotein, MRP1, and LRP in acute myeloid leukemia: A Southwest Oncology Group Study"
22. "Deletion of gene for multidrug resistance in acute myeloid leukaemia with inversion in chromosome 16: Prognostic implications"
23. "MDR1 and MRP expression in chronic B-cell lympho-proliferative disorders"
24. "Expression of the multidrug resistance-associated protein (MRP) mRNA and protein in normal peripheral blood and bone morrow haemopoietic cells"
25. "Drug resistance mechanisms in chronic lymphocytic leukemia"
26. "Chemosensitisation and drug accumulation effects of cyclosporin A, PSC-833 and verapamil in human MDR large cell lung cancer cells expressing a 190 k membrane protein distinct from P-glycoprotein"
27. "Localization of a novel multidrug resistance-associated gene in the HT1080/DR4 and H69AR human tumor cell lines"
28. "Analysis of the expression of the gene for a new putative transmembrane drug transporter in human multidrug resistant lung cancer cell lines"
29. "The prognostic significance of expression of the multidrug resistance-associated protein (MRP) in primary breast cancer"
30. "Clinical significance of the increased multidrug resistance-associated protein (MRP) gene expression in patients with primary breast cancer"
31. "Expression of the multidrug resistance protein (MRP) in squamous cell carcinome of the oesophagus and response to pre-operative chemotherapy"
32. "Multidrug resistance protein (MRP) expression in retinoblastoma correlates with the rare failure of chemotherapy despite cyclosporine for reversal of P-glycoprotein"
33. "Transcriptional suppression of multidrug resistance associated protein (MRP) gene expression by wild-type p53"
34. "Regulation of expression of the multidrug resistance protein MRP1 by p53 in human prostate cancer cells"
35. "Multidrug resistance-associated protein (MRP) expression is correlated with expression of aberrant p53 protein in colorectal cancer"
36. "Multidrug resistance-associated protein and mutant p53 protein expression in non-small cell lung cancer"
37. "Co-transfection of MDR1 and MRP antisense RNAs abolishes the drug resistance in multidrug-resistance human lung cancer cells"