Carbamazepine-risperidone interactions in patients with epilepsy

Clinical Neuropharmacology

Volumn 25, Issue 2, 2002, Pages 97-100

  Mula, Marco ^a   Monaco, Francesco ^a  

^a UNIVERSITY OF EASTERN PIEDMONT   (Italy)

Author keywords

Antiepileptic drugs; Carbamazepine; Drug interactions; Epilepsy; Risperidone

Indexed keywords

CARBAMAZEPINE; CYTOCHROME P450 2D6; CYTOCHROME P450 3A4; RISPERIDONE;

ADULT; AGED; ARTICLE; BEHAVIOR DISORDER; CLINICAL ARTICLE; DRUG BLOOD LEVEL; DRUG METABOLISM; ENZYME INHIBITION; EPILEPSY; FEMALE; HUMAN; MALE; PRIORITY JOURNAL; STEADY STATE;

ADULT; AGED; ANTICONVULSANTS; ANTIPSYCHOTIC AGENTS; CARBAMAZEPINE; CYTOCHROME P-450 CYP2D6; CYTOCHROME P-450 ENZYME SYSTEM; DRUG INTERACTIONS; DRUG THERAPY, COMBINATION; EPILEPSY; FEMALE; HUMANS; MALE; MIDDLE AGED; MIXED FUNCTION OXYGENASES; RISPERIDONE;

EID: 0036112837     PISSN: 03625664     EISSN: None     Source Type: Journal    
DOI: 10.1097/00002826-200203000-00007     Document Type: Article

References (34)

1. The efficacy and use of anticonvulsant in mood disorders
2. Risperidone
3. New developments in the pharmacologic treatment of schizoaffective disorder
4. Antipsychotic agents and bipolar disorder
5. Seizure risk associated with psychotropic drugs: Clinical and pharmacokinetic considerations
6. Carbamazepine - A double blind comparison with phenytoin
7. Carbamazepine versus propranolol for rage outburst
8. Carbamazepine in treatment of violent schizophrenics
9. Serum concentrations and side effects in psychiatric patients during risperidone therapy
10. Therapeutic drug monitoring of risperidone using a new rapid HPLC method: Reappraisal of interindividual variability factors
11. Risperidone and cytochrome P4503A
12. A pilot study on risperidone metabolism: The role of cytochrome P450 2D6 and 3A
13. Plasma concentrations of risperidone and 9-hydroxyrisperidone: Effect of comedication with carbamazepine or valproate
14. Risperidone-carbamazepine interactions: Is cytochrome P450 3A involved?
15. Metabolism of risperidone to 9-hydroxy-risperidone by human cytochromes P450 2D6 and 3A4
16. Interactions between anticonvulsant and psychoactive drugs
17. Pharmacokinetic interaction between risperidone and clozapine
18. Cross-tapering clozapine and risperidone
19. The involvement of CYP 1A2 and CYP 3A4 in the metabolism of clozapine
20. Elucidation of individual cytochrome P450 enzymes involved in the metabolism of clozapine
21. Pharmacokinetic interaction of clozapine and rifampicin in a forensic patient with atypical mycobacterial infection
22. Disposition of clozapine in man: Lack of association with debrisoquine and S-mephenytoin hydroxylation polymorphisms
23. The antipsychotic clozapine is metabolised by the polymorphic human microsomal and recombinant cytochrome P450 2D6
24. Metabolism of clozapine by cDNA-expressed human cytochrome P450 enzymes
25. Pharmacokinetic drug interaction potential of risperidone with cytochrome P450 isoenzymes as assessed by the dextromethorphan, the caffeine and the mephenytoin test
26. Pharmacokinetic-pharmacodynamic consequences and clinical relevance of cytochrome P450 3A4 inhibition
27. Increased carbamazepine plasma concentrations after fluoxetine coadministration
28. Carbamazepine coadministration with fluoxetine or fluvoxamine
29. The drug-drug interaction effects of haloperidol on plasma carbamazepine levels
30. Interaction of fluoxetine with carbamazepine
31. Adverse drug interaction between risperidone and carbamazepine in a patient with chronic schizophrenia and deficient CYP 2D6 activity
32. Different enantioselective 9-hydroxylation of risperidone by the two human CYP2D6 and CYP 3A4 enzymes