A bipartite NLS at the SHP-1 C-terminus mediates cytokine-induced SHP-1 nuclear localization in cell growth control

Blood Cells, Molecules, and Diseases

Volumn 28, Issue 1, 2002, Pages 63-74

  Yang, Wentian ^a   Tabrizi, Mina ^a   Yi, Taolin ^a  

^a LERNER RESEARCH INSTITUTE   (United States)

Author keywords

IL 4; IL 7; NLS; Proliferation; SHP 1; Tyrosine phosphatase

Indexed keywords

CYTOKINE; HYBRID PROTEIN; INTERLEUKIN 4; INTERLEUKIN 7; MEMBRANE RECEPTOR; PROTEIN TYROSINE PHOSPHATASE; PROTEIN TYROSINE PHOSPHATASE SHP 1; UNCLASSIFIED DRUG; PTPN6 PROTEIN, MOUSE; SIGNAL PEPTIDE;

AMINO ACID SEQUENCE; AMINO TERMINAL SEQUENCE; ANIMAL CELL; ARTICLE; CARBOXY TERMINAL SEQUENCE; CELL GROWTH; CELL PROLIFERATION; CONTROLLED STUDY; DEPHOSPHORYLATION; EMBRYO; HEMATOPOIETIC CELL; MOUSE; NONHUMAN; NUCLEAR LOCALIZATION SIGNAL; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN LOCALIZATION; PROTEIN PROTEIN INTERACTION; PROTEIN TARGETING; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; ACTIVE TRANSPORT; ANIMAL; CELL DIVISION; CELL STRAIN 3T3; CHEMISTRY; DRUG EFFECT; FLUORESCENCE MICROSCOPY; GENETIC TRANSFECTION; GENETICS; HEMATOPOIETIC STEM CELL; METABOLISM; NUCLEOTIDE SEQUENCE; PHYSIOLOGY;

3T3 CELLS; ACTIVE TRANSPORT, CELL NUCLEUS; ANIMALS; BASE SEQUENCE; CELL DIVISION; CYTOKINES; HEMATOPOIETIC STEM CELLS; INTERLEUKIN-4; INTERLEUKIN-7; INTRACELLULAR SIGNALING PEPTIDES AND PROTEINS; MICE; MICROSCOPY, FLUORESCENCE; NUCLEAR LOCALIZATION SIGNALS; PROTEIN-TYROSINE-PHOSPHATASE; RECOMBINANT FUSION PROTEINS; SHP1 PROTEIN TYROSINE PHOSPHATASE; TRANSFECTION;

EID: 0036102113     PISSN: 10799796     EISSN: None     Source Type: Journal    
DOI: 10.1006/bcmd.2002.0485     Document Type: Article

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