Determination of redundancy and systems properties of the metabolic network of Helicobacter pylori using genome-scale extreme pathway analysis

Genome Research

Volumn 12, Issue 5, 2002, Pages 760-769

  Price, Nathan D ^a   Papin, Jason A ^a   Palsson, Bernhard Ø ^a  

^a UNIVERSITY OF CALIFORNIA SAN DIEGO   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACID; AMMONIA; ASPARAGINE; ASPARTIC ACID; CYSTEINE; GLUTAMIC ACID; GLUTAMINE; GLYCINE; LYSINE; NITROGEN; PROLINE; RIBONUCLEOTIDE; SERINE; THREONINE; TRYPTOPHAN; TYROSINE;

ACIDITY; AMINO ACID METABOLISM; AMINO ACID SYNTHESIS; AMMONIA FORMATION; ARTICLE; BACTERIAL GENOME; BACTERIAL METABOLISM; CONTROLLED STUDY; GENOME ANALYSIS; GENOTYPE PHENOTYPE CORRELATION; HABITAT QUALITY; HAEMOPHILUS INFLUENZAE; HELICOBACTER PYLORI; NITROGEN METABOLISM; NONHUMAN; PH; PRIORITY JOURNAL;

BACTERIA (MICROORGANISMS); HAEMOPHILUS; HAEMOPHILUS INFLUENZAE; HELICOBACTER; HELICOBACTER PYLORI;

EID: 0036100243     PISSN: 10889051     EISSN: None     Source Type: Journal    
DOI: 10.1101/gr.218002     Document Type: Article

References (36)

1. Genomic-sequence comparison of two unrelated isolates of the human gastric pathogen Helicobacter pylori
2. Epidemiological features of Helicobacter pylori infection in developing countries
3. Flux analysis of underdetermined metabolic networks: The quest for the missing constraints
4. Reconstruction of amino acid biosynthesis pathways from the complete genome sequence
5. Gene number: What if there are only 30,000 human genes?
6. Helicobacter pylori infection, a paradigm for chronic mucosal inflammation: Pathogenesis and implications for eradication and prevention
7. Metabolic modeling of microbial strains in silico
8. Systems properties of the Haemophilus influenzae Rd metabolic genotype
9. Metabolic flux balance
10. The control of flux
11. Pathway databases: A case study in computational symbolic theories
12. HinCyc: A knowledge base of the complete genome and metabolic pathways of H
13. Integrated pathway-genome databases and their role in drug discovery
14. The physiology and metabolism of the human gastric pathogen Helicobacter pylori
15. Pathway analysis in metabolic databases via differential metabolic display (DMD)
16. Pathway analysis, engineering and physiological considerations for redirecting central metabolism
17. Computer-sided synthesis of niochemical pathways
18. Nucleotide metabolism
19. Helicobacter pylori rocF is required for arginase activity and acid protection in vitro but is not essential for colonization of mice or for urease activity
20. Nutritional requirements for growth of Helicobacter pylori
21. Chemical composition of Escherichia coli
22. Global properties of the metabolic map of Escherichia coli
23. WIT: Integrated system for high-throughput genome sequence analysis and metabolic reconstruction
24. The genome-scale metabolic extreme pathway structure in Haemophilus influenzae shows significant network redundancy
25. Characteristics of Helicobacter pylori growth in a defined medium and determination of its amino acid requirements
26. "On systems biology and the pathway analysis of metabolic networks"
27. Assessment of the metabolic capabilities of Haemophilus influenzae Rd through a genome-scale pathway analysis
28. Metabolic pathway analysis: Basic concepts and scientific applications in the post-genomic era
29. Theory for the systemic definition of metabolic pathways and their use in interpreting metabolic function from a pathway-oriented perspective
30. Detection of elementary flux modes in biochemical networks: A promising tool for pathway analysis and metabolic engineering
31. MPW: The metabolic pathways database
32. Amino acid utilisation and deamination of glutamine and asparagine by Helicobacter pylori
33. The complete genome sequence of the gastric pathogen Helicobacter pylori
34. Functional versatility and molecular diversity of the metabolic map of Escherichia coli
35. Metabolic flux balancing: Basic concepts, scientific and practical use