Detection of a variant metallo-β-lactamase, IMP-10, from two unrelated strains of Pseudomonas aeruginosa and an Alcaligenes xylosoxidans strain

Antimicrobial Agents and Chemotherapy

Volumn 46, Issue 6, 2002, Pages 2014-2016

  Iyobe, Shizuko ^a   Kusadokoro, Haruko ^a   Takahashi, Ayako ^a   Yomoda, Sachie ^a   Okubo, Toyoji ^a   Nakamura, Akio ^a   O'Hara, Koji ^a  

^a GUNMA UNIVERSITY   (Japan)

Author keywords

[No Author keywords available]

Indexed keywords

AMPICILLIN; AZTREONAM; BETA LACTAMASE; BETA LACTAMASE IMP 10; CARBENICILLIN; CEFALORIDINE; CEFALOTIN; CEFOTAXIME; CEFTAZIDIME; IMIPENEM; MEROPENEM; PENICILLIN DERIVATIVE; PENICILLIN G; PIPERACILLIN; TICARCILLIN; TIMENTIN; UNCLASSIFIED DRUG;

ACHROMOBACTER XYLOSOXIDANS; AMINO ACID SUBSTITUTION; ANTIBIOTIC RESISTANCE; ARTICLE; BACTERIAL GENETICS; BACTERIAL STRAIN; CONTROLLED STUDY; DRUG HYDROLYSIS; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME KINETICS; ENZYME PURIFICATION; ENZYME SPECIFICITY; MICHAELIS CONSTANT; MINIMUM INHIBITORY CONCENTRATION; NONHUMAN; NUCLEIC ACID BASE SUBSTITUTION; NUCLEOTIDE SEQUENCE; POINT MUTATION; PRIORITY JOURNAL; PSEUDOMONAS AERUGINOSA; STRAIN DIFFERENCE;

ALCALIGENES; BETA-LACTAMASES; DNA, BACTERIAL; DRUG RESISTANCE, MICROBIAL; IMIPENEM; KINETICS; PLASMIDS; POINT MUTATION; PSEUDOMONAS AERUGINOSA; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; SPECTROPHOTOMETRY, ULTRAVIOLET; THIENAMYCINS;

EID: 0036096012     PISSN: 00664804     EISSN: None     Source Type: Journal    
DOI: 10.1128/AAC.46.6.2014-2016.2002     Document Type: Article

References (24)

1. Bacterial plasmids
2. A functional classification scheme for β-lactamases and its correlation with molecular structure
3. IMP-4, a novel metallo-β-lactamase from nosocomial Acinetobacter spp. collected in Hong Kong between 1994 and 1998
4. Crystal structure of the IMP-1 metallo-β-lactamase from Pseudomonas aeruginosa and its complex with a mercaptocarboxyl inhibitor: Binding determinants of a potent, broad-spectrum inhibitor
5. Mobile gene cassettes and integrons: Capture and spread of genes by site-specific recombination
6. Occurrence of a new metallo-β-lactamase IMP-4 carried on aconjugative plasmid in Citrobacter youngae from the People's Repulic of China
7. IMP
8. Amino acid substitutions in a variant of IMP-1 metallo-β-lactamase
9. Cloning and expression in Enterobacteriaceae of the extended-spectrum β-lactamase gene from a Pseudomonas aeruginosa plasmid
10. Insertion of a carbapenemase gene cassette into an integron of a Pseudomonas aeruginosa plasmid
11. Biochemical characterization of the Pseudomonas aeruginosa 101/1477 metallo-β-lactamase IMP-1 produced by Escherichia coli
12. PCR mapping of integrons reveals several novel combinations of resistance genes
13. Purification and characterization of metallo-β-lactamase from Serratia marcescens
14. Molecular characterization of an enterobacterial metallo-β-lactamase found in a clinical isolate of Serratia marcescens that shows imipenem resistance
15. Carbapenem-hydrolyzing β-lactamases
16. Gene cassettes: A new class of mobile element
17. IMP allelic variants carried by gene cassettes of different phylogeny
18. Identification and characterization of class 1 integrons in bacteria from an aquatic environment
19. IMP) in gram-negative rods resistant to broad-spectrum β-lactams
20. Detection of carbapenemase-producing Acinetobacter baumannii in a hospital
21. High-copy-number and low-copy-number plasmid vectors for lacZ α-complementation and chloramphenicol- or kanamycin-resistance selection
22. Transferable imipenem resistance in Pseudomonas aeruginosa
23. Identification of a plasmid encoding SHV-12, TEM-1, and a variant of IMP-2 metallo-β-lactamase, IMP-8, from a clinical isolate of Klebsiella pneumoniae
24. Plasmid-encoded metallo-β-lactamase (IMP-6) conferring resistance to carbapenems, especially meropenem