Acid suppression therapy may not alter malignant progression in Barrett's metaplasia showing p53 protein accumulation

American Journal of Gastroenterology

Volumn 97, Issue 6, 2002, Pages 1340-1345

  Carlson, Nicole ^c   Lechago, Juan ^c   Richter, Joel ^c   Sampliner, Richard E ^c   Peterson, Leif ^c   Santella, Regina M ^c   Goldblum, John R ^c   Falk, Gary W ^c   Ertan, Atilla ^c   Younes, Mamoun ^a,b  

^a HOUSTON METHODIST HOSPITAL   (United States)

^b BAYLOR COLLEGE OF MEDICINE   (United States)

^c NONE

Author keywords

[No Author keywords available]

Indexed keywords

8 HYDROXYDEOXYGUANOSINE; HISTAMINE H2 RECEPTOR ANTAGONIST; PROTEIN P53; PROTON PUMP INHIBITOR;

ARTICLE; BARRETT ESOPHAGUS; CANCER GROWTH; CLINICAL ARTICLE; DNA DAMAGE; DYSPLASIA; ESOPHAGUS BIOPSY; FEMALE; HUMAN; HUMAN TISSUE; IMAGE ANALYSIS; IMMUNOHISTOCHEMISTRY; MALE; METAPLASIA; PLOIDY; PRIORITY JOURNAL;

BARRETT ESOPHAGUS; BIOPSY; DISEASE PROGRESSION; DNA; ESOPHAGUS; FEMALE; GASTRIC ACID; HUMANS; MALE; METAPLASIA; PLOIDIES; PRECANCEROUS CONDITIONS; TUMOR SUPPRESSOR PROTEIN P53;

EID: 0036089603     PISSN: 00029270     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0002-9270(02)04126-6     Document Type: Article

References (26)

1. Adenocarcinoma complicating columnar epithelium-lined (Barrett's) esophagus
2. Barrett's esophagus. Comparison of benign and malignant cases
3. Conservative operations for peptic esophagitis with stenosis in columnar-lined lower esophagus
4. Continuing climb in rates of esophageal adenocarcinoma: An update
5. National Cancer Data Base report on esophageal carcinoma
6. Adenocarcinoma in Barrett's esophagus. A clinicopathologic study of 65 cases
7. Effect of antireflux operation on Barrett's mucosa
8. Long-term results of classic antireflux surgery in 152 patients with Barrett's esophagus: Clinical, radiologic, endoscopic, manometric, and acid reflux test analysis before and late after operation
9. Development of adenocarcinoma in Barrett's oesophagus after successful antireflux surgery
10. Barretts's esophagus: Does an antireflux procedure reduce the need for endoscopic surveillance?
11. Regression and progression of Barrett's oesophagus after antireflux surgery
12. Adenocarcinoma arising in Barrett's esophagus after total gastrectomy
13. Adenocarcinoma in Barrett's esophagus following total resection of the gastric remnant: A case report
14. Early esophageal adenocarcinoma arising in a short segment of Barrett's mucosa after total gastrectomy
15. Conservative treatment versus antireflux surgery in Barrett's oesophagus: Long-term results of a prospective study
16. Normalization of esophageal pH with high-dose proton pump inhibitor therapy does not result in regression of Barrett's esophagus
17. Esophagitis in Sprague-Dawley rats is mediated by free radicals
18. Reflux esophagitis in humans is mediated by oxygen-derived free radicals
19. Reflux esophagitis in humans is a free radical event
20. Protection against chemically-induced oxidative gastrointestinal tissue injury in rats by bismuth salts
21. Stress, diet, and alcohol-induced oxidative gastrointestinal mucosal injury in rats and protection by bismuth subsalicylate
22. Relationship between dysplasia, p53 protein accumulation, DNA ploidy, and Glutl overexpression in Barrett metaplasia
23. Barrett's esophagus, dysplasia, and adenocarcinoma
24. Immunoperoxidase detection of 8-hydroxydeoxyguanosine in aflatoxin B1-treated rat liver and human oral mucosal cells
25. p53 protein accumulation in Barrett's metaplasia, dysplasia, and carcinoma: A follow-up study
26. p53 protein accumulation is a specific marker of malignant potential in Barrett's metaplasia