Co-stimulation and modulation of the ensuing immune response

Veterinary Immunology and Immunopathology

Volumn 87, Issue 3-4, 2002, Pages 123-130

  Howard, C J ^a   Hope, J C ^a   Stephens, S A ^a   Gliddon, D R ^a   Brooke, G P ^a  

^a INSTITUTE FOR ANIMAL HEALTH   (United Kingdom)

Author keywords

Antigen presenting cells; Bovine immunology; Co stimulatory molecules; Dendritic cells; Immunomodulation

Indexed keywords

B7 ANTIGEN; CD40 ANTIGEN; CD47 ANTIGEN; CD86 ANTIGEN; CHEMOKINE; DIPEPTIDYL PEPTIDASE IV; INTERLEUKIN 10; INTERLEUKIN 12; LIPOPOLYSACCHARIDE; PHOSPHOPROTEIN PHOSPHATASE; PROTEIN TYROSINE PHOSPHATASE SHP 2; TUMOR NECROSIS FACTOR ALPHA; UNCLASSIFIED DRUG;

ANTIGEN PRESENTATION; BOVIDS; CANNULATION; CELL ACTIVATION; CELL FUNCTION; CELL INTERACTION; CELL POPULATION; CELL TYPE; CONFERENCE PAPER; CROSS LINKING; CYTOKINE PRODUCTION; DENDRITIC CELL; ENZYME ACTIVITY; IMMUNE RESPONSE; IMMUNITY; IMMUNOMODULATION; IMMUNOSTIMULATION; LYMPH; LYMPHOCYTE SUBPOPULATION; NONHUMAN; PROTEIN PHOSPHORYLATION; RODENT; SKIN; T LYMPHOCYTE; TH1 CELL;

ANIMALS; ANTIGENS, CD; ANTIGENS, CD26; ANTIGENS, CD47; ANTIGENS, DIFFERENTIATION; CARRIER PROTEINS; CD4-POSITIVE T-LYMPHOCYTES; DENDRITIC CELLS; INTERLEUKIN-1; INTERLEUKIN-12; MEMBRANE GLYCOPROTEINS; NEURAL CELL ADHESION MOLECULE L1; NEURAL CELL ADHESION MOLECULES; RECEPTORS, IMMUNOLOGIC; TH1 CELLS; TH2 CELLS;

BOS TAURUS; BOVINAE; RODENTIA;

EID: 0036088741     PISSN: 01652427     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-2427(02)00043-0     Document Type: Conference Paper

References (18)

1. Characterisation cloning and sequencing of a novel molecule MyD-1, expressed on cattle and human antigen presenting cells
2. Cloning of two members of the SIRP alpha family of protein tyrosine phosphatase binding proteins in cattle that are expressed on monocytes and a subpopulation of dendritic cells and which mediate binding to CD4 T cells
3. The peptidase CD26 is expressed by a subpopulation of dendritic cells in afferent lymph
4. + T-cell responses to Mycobacterium bovis and M. avium antigens in Bacille Calmette Guerin vaccinated and nonvaccinated cattle
5. Dendritic cells: Implications on function from studies of the afferent lymph veiled cell
6. Identification of two distinct populations of dendritic cells in afferent lymph that vary in their ability to stimulate T cells
7. Dendritic cell lineage, plasticity and cross regulation
8. Role of CD47 as a marker of self on red blood cells
9. Regulation of receptor tyrosine kinase signaling by protein tyrosine phosphatases
10. CD47 signals T cell death
11. Truncation of macrophage derived chemokine by CD26/dipeptidyl-peptidase IV beyond its predicted cleavage site affects chemotactic activity and CC chemokine receptor 4 interaction
12. Signal-regulatory protein alpha (SIRPalpha) but not SIRPbeta is involved in T-cell activation, binds to CD47 with high affinity, and is expressed on immature CD34(+)CD38(-) hematopoietic cells
13. A new non-lineage specific antigen with an M(r) of 115 and 39 kDa present on bovine leukocytes identified by monoclonal antibodies within BoWC10
14. Cross-reactivity with bovine cells of monoclonal antibodies
15. The dendritic cell system and its role in immunogenicity
16. Natural truncation of RANTES abolishes signalling through the CC chemokine receptors CCR1 and CCR3, impairs its chemotactic potency and generates a CC chemokine inhibitor
17. CD47 is a ligand for rat macrophage membrane signal regulatory protein SIRP (OX41) and human SIRPalpha 1
18. T cell stimulation via CD47: Agonistic and antagonistic effects of CD47 monoclonal antibody 1/1A4