Activation of the Pseudomonas aeruginosa type III secretion system requires an intact pyruvate dehydrogenase aceAB operon

Infection and Immunity

Volumn 70, Issue 7, 2002, Pages 3973-3977

  Dacheux, Denis ^a   Epaulard, Olivier ^a   De Groot, Arjan ^a   Guery, Benoit ^a   Leberre, Rozen ^a   Attree, Ina ^a   Polack, Benoit ^a   Toussaint, Bertrand ^a  

^a GRENOBLE UNIVERSITY HOSPITAL   (France)

Author keywords

[No Author keywords available]

Indexed keywords

CALCIUM; PYRUVATE DEHYDROGENASE; VIRULENCE FACTOR;

ARTICLE; BACTERIAL VIRULENCE; CYSTIC FIBROSIS; CYTOTOXICITY; ENZYME SUBUNIT; GENE EXPRESSION; MUTAGENESIS; NEUTROPHIL; NONHUMAN; OPERON; PRIORITY JOURNAL; PROTEIN FUNCTION; PSEUDOMONAS AERUGINOSA; TRANSCRIPTION INITIATION;

ANIMALS; BACTERIAL PROTEINS; CYSTIC FIBROSIS; DIHYDROLIPOYLLYSINE-RESIDUE ACETYLTRANSFERASE; DISEASE MODELS, ANIMAL; DNA-BINDING PROTEINS; HUMANS; L-LACTATE DEHYDROGENASE; MUTAGENESIS, INSERTIONAL; NEUTROPHILS; OPERON; PHOSPHOPROTEIN PHOSPHATASE; PNEUMONIA, BACTERIAL; PORE FORMING CYTOTOXIC PROTEINS; PROTEIN KINASES; PSEUDOMONAS AERUGINOSA; PSEUDOMONAS INFECTIONS; PYRUVATE DEHYDROGENASE COMPLEX; RATS; RATS, SPRAGUE-DAWLEY; TRANS-ACTIVATORS;

EID: 0036088392     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.70.7.3973-3977.2002     Document Type: Article

References (20)

1. Cell death of human polymorphonuclear neutrophils induced by a Pseudomonas aeruginosa cystic fibrosis isolate requires a functional type III secretion system
2. Expression of ExsA in trans confers type III secretion system-dependent cytotoxicity on noncytotoxic Pseudomonas aeruginosa cystic fibrosis isolates
3. Poreforming activity of type III system-secreted proteins leads to oncosis of Pseudomonas aeruginosa-infected macrophages
4. Pseudomonas aeruginosa cystic fibrosis isolates induce rapid, type III secretion-dependent, but ExoU-independent, oncosis of macrophages and polymorphonuclear neutrophils
5. Isolation of an IHF-deficient mutant of a Pseudomonas aeruginosa mucoid isolate and evaluation of the role of IHF in algD gene expression
6. Mini-Tn5 transposon derivatives for insertion mutagenesis, promoter probing, and chromosomal insertion of cloned DNA in gram-negative eubacteria
7. Periplasmic protein thiol:disulfide oxidoreductases of Escherichia coli
8. Replication of an origin-containing derivative of plasmid RK2 dependent on a plasmid function provided in trans
9. The exoenzyme S regulon of Pseudomonas aeruginosa
10. Type III protein secretion systems in bacterial pathogens of animals and plants
11. Pathogenicity of microbes associated with cystic fibrosis
12. Isolation and properties of pyruvate dehydrogenase complex mutants of Pseudomonas aeruginosa PAO
13. Inorganic polyphosphate is needed for swimming, swarming, and twitching motilities of Pseudomonas aeruginosa
14. In Azotobacter vinelandii, the E1 subunit of the pyruvate dehydrogenase complex binds fpr promoter region DNA and ferredoxin I
15. Active and passive immunization with the Pseudomonas V antigen protects against type III intoxication and lung injury
16. Complete genome sequence of Pseudomonas aeruginosa PA01, an opportunistic pathogen
17. Acetylornithinase in Escherichia coli: Partial purification and some properties
18. Specific binding of the E2 subunit of pyruvate dehydrogenase to the upstream region of Bacillus thuringiensis protoxin genes
19. Exoenzyme S of Pseudomonas aeruginosa is secreted by a type III pathway
20. Cloning and characterization of polyphosphate kinase and exopolyphosphatase genes from Pseudomonas aeruginosa 8830