Expression of the Plasmodium falciparum immunodominant epitope (NANP)4 on the surface of Salmonella enterica using the autotransporter MisL

Infection and Immunity

Volumn 70, Issue 7, 2002, Pages 3611-3620

  Ruiz Pérez, Fernando ^a   León Kempis, Rocío ^a   Santiago Machuca, Araceli ^a   Ortega Pierres, Guadalupe ^a   Barry, Eileen ^a   Levine, Myron ^a   González Bonilla, César ^a  

^a INSTITUTO MEXICANO DEL SEGURO SOCIAL   (Mexico)

Author keywords

[No Author keywords available]

Indexed keywords

ANTIBODY; BACTERIAL PROTEIN; EPITOPE; PROTEIN CSP; PROTEIN MISL; PROTEIN NANP4; PROTEIN NIR; SIGNAL PEPTIDE; UNCLASSIFIED DRUG;

ANTIGEN ANTIBODY REACTION; ARTICLE; CARBOXY TERMINAL SEQUENCE; CONTROLLED STUDY; ESCHERICHIA COLI; GENE AMPLIFICATION; GENE EXPRESSION; GENE INDUCTION; GENE INSERTION; GRAM NEGATIVE BACTERIUM; IMMUNOGENICITY; MOLECULAR CLONING; NONHUMAN; PATHOGENICITY; PLASMODIUM FALCIPARUM; PRIORITY JOURNAL; PROTEIN DOMAIN; PROTEIN TRANSPORT; SALMONELLA ENTERICA; SEQUENCE ALIGNMENT; SEQUENCE HOMOLOGY; SEROTYPE; SPOROZOITE;

AMINO ACID SEQUENCE; ANIMALS; ANTIBODIES, PROTOZOAN; ANTIGENS, PROTOZOAN; BACTERIAL PROTEINS; BASE SEQUENCE; CARRIER PROTEINS; CELL MEMBRANE; DNA, COMPLEMENTARY; EPITOPES, B-LYMPHOCYTE; GENE EXPRESSION; GENETIC ENGINEERING; GENETIC VECTORS; IMMUNODOMINANT EPITOPES; MALARIA VACCINES; MEMBRANE TRANSPORT PROTEINS; MICE; MICE, INBRED BALB C; MOLECULAR SEQUENCE DATA; PEPTIDES; PLASMODIUM FALCIPARUM; PROTOZOAN PROTEINS; RECOMBINANT FUSION PROTEINS; SALMONELLA TYPHIMURIUM; SEQUENCE HOMOLOGY, AMINO ACID; VACCINES, SYNTHETIC;

EID: 0036084379     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/IAI.70.7.3611-3620.2002     Document Type: Article

References (37)

1. The sigA gene which is borne on the she pathogenicity island of Shigella flexneri 2a encodes an exported cytopathic protease involved in intestinal fluid accumulation
2. Cloning and expression of an adhesin (AIDA-I) involved in diffuse adherence of enteropathogenic Escherichia coli
3. The SPI-3 pathogenicity island of Salmonella enterica
4. A rapid and sensitive method for the quantitation of microgram quantities of protein utilizing the principle of protein-dye binding
5. Use of the nirB promoter to direct the stable expression of heterologous antigens in Salmonella oral vaccine strains: Development of a single-dose oral tetanus vaccine
6. Relationship between the Tsh autotransporter and pathogenicity of avian Escherichia coli and localization and analysis of the Tsh genetic region
7. A murine model of intranasal immunization to assess the immunogenicity of attenuated Salmonella typhi live vector vaccines in stimulating serum anti-body responses to expressed foreign antigens
8. Salmonella typhi vaccine strain CVD 908 expressing the circumsporozoite protein of Plasmodium falciparum: Strain construction and safety and immunogenicity
9. Identification of sat, an autotransporter toxin produced by uropathogenic Escherichia coli
10. The great escape: Structure and function of the autotransporter proteins
11. Characterization of Pic, a secreted protease of Shigella flexneri and entero-aggregative Escherichia coli
12. Autotransporter proteins, evolution and redefining protein secretion
13. Virulence functions of autotransporter proteins
14. Safety and immunogenicity in man of a synthetic peptide malaria vaccine against Plasmodium falciparum sporozoites
15. Superior efficacy of secreted over somatic antigen display in recombinant Salmonella vaccine induced protection against listeriosis
16. Aromatic-dependent Salmonella typhimurium are non-virulent and effective as live vaccines
17. Construction of genetically defined double aro mutants of Salmonella typhi
18. The shdA gene is restricted to serotypes of Salmonella enterica subspecies I and contributes to efficient and prolonged fecal shedding
19. Characterization of the Neisseria IgA beta-core. The essential unit for outer membrane targeting and extracellular protein secretion
20. Cell surface presentation of recombinant (poly-)peptides including functional T-cell epitopes by the AIDA autotransporter system
21. Cleavage of structural proteins during the assembly of the head of bacteriophage T4
22. Autodisplay: Functional display of active B-lactamase on the surface of Escherichia coli by the AIDA-I autotransporter
23. Pertactin, an Arg-Gly-Asp-containing Bordetella pertussis surface protein that promotes adherence of mammalian cells
24. Identification of a glycoprotein produced by enterotoxigenic Escherichia coli
25. Autodisplay: One-component system for efficient surface display and release of soluble recombinant proteins from Escherichia coli
26. Characterization of the essential transport function of the AIDA-I autotransporter and evidence supporting structural predictions
27. Experimental basis for the development of a synthetic vaccine against Plasmodium falciparum malaria sporozoites
28. High level heterologous expression in E. coli using the anaerobically-activated nirB promoter
29. Gene structure and extracellular secretion of Neisseria gonorrhoeae IgA protease
30. Characterizing aquatic bacteria according to population, cell size, and apparent DNA content by flow cytometry
31. Oral Salmonella typhimurium vaccine expressing circumsporozoite protein protects against malaria
32. The Haemophilus influenzae Hia adhesin is an autotransporter protein that remains uncleaved at the C terminus and fully cell associated
33. Extracellular transport of VirG protein in Shigella
34. Direct flow cytometry of anaerobic bacteria in human feces
35. Probing secretion and translocation of a beta-autotransporter using a reporter single-chain Fv as a cognate passenger domain
36. Synthetic peptides as antigens for the detection of humoral immunity to Plasmodium falciparum sporozoites