-
1
-
-
0004324724
-
Facts and Figures
-
American Cancer Society
-
(2002)
-
-
-
7
-
-
0027131199
-
A link between breast cancer and local estrogen biosynthesis suggested by quantification of breast adipose tissue aromatase cytochrome P450 transcripts using competitive polymerase chain reaction after reverse transcription
-
(1993)
J. Clin. Endocrinol. Metab
, vol.77
, pp. 1622-1628
-
-
Bulun, S.E.1
Price, T.M.2
Aitken, J.3
-
19
-
-
0029777430
-
Regulation of arachidonic acid metabolism, aromatase activity and growth in human breast cancer cells by interleukin-1b and phorbol ester: Dissociation of a mediatory role for prostaglandin E2 in the autocrine control of cell function
-
(1996)
Int. J. Cancer
, vol.67
, pp. 684-689
-
-
Hughes, R.1
Timmermans, P.2
Schrey, M.P.3
-
23
-
-
0034654120
-
Peroxisome proliferator-activated receptor gamma ligands inhibit estrogen biosynthesis in human breast adipose tissue: Possible implications for breast cancer therapy
-
(2000)
Cancer Res
, vol.60
, pp. 1604-1608
-
-
Rubin, G.L.1
Zhao, Y.2
Kalus, A.M.3
-
24
-
-
0031772702
-
Mechanisms of action of anti-estrogens: Relevance to clinical benefits and risks
-
(1998)
Cancer Invest
, vol.16
, pp. 604-611
-
-
Carmichael, P.L.1
-
33
-
-
0001828104
-
Aromatase inhibitors: Specific inhibitors of oestrogen biosynthesis
-
(1988)
, pp. 534-571
-
-
Covey, D.F.1
-
43
-
-
0023245423
-
Effects of the aromatase inhibitor 7 α-(4′-amino)phenylthio-4-androstene-3,17-dione in MCF-7 human mammary carcinoma cell culture
-
(1987)
Cancer Res
, vol.47
, pp. 4548-4551
-
-
Brueggemeier, R.W.1
Katlic, N.E.2
-
45
-
-
0024272363
-
Effects of the aromatase inhibitor 7 α-(4′-amino)phenylthio-4-androstene-3,17-dione on 7,12-dimethylbenz(a)anthracene-induced mammary carcinoma in rats
-
(1988)
Cancer Res
, vol.48
, pp. 6808-6810
-
-
Brueggemeier, R.W.1
Li, P.K.2
-
56
-
-
0022259362
-
Effects of aromatase inhibitors, aminoglutethimide and 4-hydroxyandrostenedione on cyclic rats and rats with 7,12-dimethylbenz(a)anthracene-induced mammary tumors
-
(1985)
Cancer Res
, vol.45
, pp. 2425-2428
-
-
Wing, L.Y.1
Garrett, W.M.2
Brodie, A.M.3
-
60
-
-
0028073150
-
Aromatase inhibition: Basic concepts and the pharmacodynamics of formestane
-
(1994)
Ann. Oncol
, vol.5
, Issue.SUPPL. 7
-
-
Dowsett, M.1
-
61
-
-
0022470876
-
Metabolism of the aromatase inhibitor 4-hydroxyandrostenedione in vivo. Identification of the glucuronide as a major urinary metabolite in patients and biliary metabolite in the rat
-
(1986)
J. Steroid Biochem
, vol.24
, pp. 619-622
-
-
Goss, P.E.1
Jarman, M.2
Wilkinson, J.R.3
-
62
-
-
0029856576
-
Formestane, a review of its pharmacological properties and clinical efficacy in the treatment of postmenopausal breast cancer
-
(1996)
Drugs Aging
, vol.9
, pp. 292-306
-
-
Wiseman, L.R.1
Goa, K.L.2
-
63
-
-
0019449456
-
Enzyme-generated intermediates derived from 4-androstene-3,6,17-trione and 1,4,6-androstatriene-3,17-dione cause a time-dependent decrease in human placental aromatase activity
-
(1981)
Endocrinology
, vol.108
, pp. 1597-1599
-
-
Covey, D.F.1
Hood, W.F.2
-
64
-
-
0020038789
-
Aromatase enzyme catalysis is involved in the potent inhibition of estrogen biosynthesis caused by 4-ace
-
(1982)
Mol. Pharmacol
, vol.21
, pp. 173-180
-
-
Covey, D.F.1
Hood, W.F.2
-
74
-
-
0027256092
-
Experience with aromatase inhibitors in the treatment of advanced breast cancer
-
(1993)
Cancer Treat. Rev
, vol.19
, Issue.SUPPL. B
, pp. 37-44
-
-
Hoffken, K.1
-
82
-
-
0027992634
-
Effects of fadrozole (CGS 16949A) and letrozole (CGS 20267) on the inhibition of aromatase activity in breast cancer patients
-
(1994)
Breast Cancer Res. Treat
, vol.30
, pp. 95-102
-
-
Demers, L.M.1
-
83
-
-
0016211635
-
Proceedings: Medical adrenalectomy using aminoglutethimide and dexamethasone in advanced breast cancer
-
(1974)
Cancer
, vol.33
, pp. 503-512
-
-
Lipton, A.1
Santen, R.J.2
-
88
-
-
0035345731
-
Aromatase inhibition and anti-estrogen therapy in early breast cancer treatment and chemoprevention
-
(2001)
Oncology
, vol.15
, pp. 28-34
-
-
Ingle, J.N.1
-
89
-
-
0034984594
-
Endocrine therapy in the treatment of metastatic breast cancer
-
(2001)
Semin. Oncol
, vol.28
, pp. 291-304
-
-
Buzdar, A.U.1
-
93
-
-
0029804714
-
Influence of anastrozole (Arimidex), a selective, non-steroidal aromatase inhibitor, on in vivo aromatization and plasma oestrogen levels in postmenopausal women with breast cancer
-
(1996)
Br. J. Cancer
, vol.74
, pp. 1286-1291
-
-
Geisler, J.1
King, N.2
Dowsett, M.3
-
94
-
-
9244245282
-
A randomized trial comparing two doses of the new selective aromatase inhibitor anastrozole (Arimidex) with megestrol acetate in postmenopausal patients with advanced breast cancer
-
(1996)
Eur. J. Cancer
, vol.32 A
, pp. 404-412
-
-
Jonat, W.1
Howell, A.2
Blomqvist, C.3
-
95
-
-
0031054095
-
A Phase III trial comparing anastrozole (1 and 10 milligrams), a potent and selective aromatase inhibitor, with megestrol acetate in postmenopausal women with advanced breast carcinoma
-
Arimidex Study Group
-
(1997)
Cancer
, vol.79
, pp. 730-739
-
-
Buzdar, A.U.1
Jones, S.E.2
Vogel, C.L.3
-
96
-
-
8944237006
-
Anastrozole, a potent and selective aromatase inhibitor, versus megestrol acetate in postmenopausal women with advanced breast cancer: Results of overview analysis of two Phase III trials
-
Arimidex Study Group
-
(1996)
J. Clin. Oncol
, vol.14
, pp. 2000-2011
-
-
Buzdar, A.1
Jonat, W.2
Howell, A.3
-
98
-
-
0034669484
-
Anastrozole is superior to tamoxifen as firstline therapy for advanced breast cancer in postmenopausal women: Results of a North American multicenter randomized trial
-
Arimidex Study Group
-
(2000)
J. Clin. Oncol
, vol.18
, pp. 3758-3767
-
-
Nabholtz, J.M.1
Buzdar, A.2
Pollak, M.3
-
101
-
-
0031943424
-
Letrozole, a new oral aromatase inhibitor for advanced breast cancer: Double-blind randomized trial showing a dose effect and improved efficacy and tolerability compared with megestrol acetate
-
(1998)
J. Clin. Oncol
, vol.16
, pp. 453-461
-
-
Dombernowsky, P.1
Smith, I.2
Falkson, G.3
-
102
-
-
0035879215
-
Phase III, multicenter, double-blind, randomized study of letrozole, an aromatase inhibitor, for advanced breast cancer versus megestrol acetate
-
(2001)
J. Clin. Oncol
, vol.19
, pp. 3357-3366
-
-
Buzdar, A.1
Douma, J.2
Davidson, N.3
-
103
-
-
0343584508
-
Superior efficacy of letrozole versus tamoxifen as first-line therapy for postmenopausal women with advanced breast cancer: Results of a Phase III study of the International Letrozole Breast Cancer Group
-
(2001)
J. Clin. Oncol
, vol.19
, pp. 2596-2606
-
-
Mouridsen, H.1
Gershanovich, M.2
Sun, Y.3
-
109
-
-
33749116195
-
The ATAC (Arimidex, Tamoxifen, Alone or in Combination) adjuvant breast cancer trial in postmenopausal women
-
(2001)
Breast Cancer Res. Treat
, vol.69
, pp. 210
-
-
Baum, M.1
-
110
-
-
0005921855
-
Letrozole (Femara) is a more effective antiproliferative agent than tamoxifen irrespective of ErbB1 and/or ErbB2 positive status: Evidence from a Phase III randomized trial of neoadjuvant endocrine therapy for with estrogen receptor positive primary breast cancer
-
(2001)
Breast Cancer Res. Treat
, vol.69
, pp. 211
-
-
Ellis, M.J.1
Jaenicke, F.2
Ilombart-Cussac, A.3
-
113
-
-
0028594068
-
Chemopreventive effects of the aromatase inhibitors vorozole (R-83842) and 4-hydroxyandrostenedione in the methylnitrosourea (MNU)-induced mammary tumor model in Sprague-Dawley rats
-
(1994)
Carcinogenesis
, vol.15
, pp. 2775-2780
-
-
Lubet, R.A.1
Steele, V.E.2
Casebolt, T.L.3
|