Improvement of the movement and host range properties of a plant virus vector through DNA shuffling

Plant Journal

Volumn 30, Issue 5, 2002, Pages 593-600

  Toth, Rachel L ^a   Pogue, Gregory P ^b   Chapman, Sean ^a  

^a SCOTTISH CROP RESEARCH INSTITUTE   (United Kingdom)

^b Large Scale Biology Corporation   (United States)

Author keywords

Cell to cell movement; DNA shuffling; Molecular breeding; Movement protein; Tobacco mosaic virus; Vector

Indexed keywords

CELLS; CLONING; DNA; FLUORESCENCE; VIRUSES;

CELL-TO-CELL MOVEMENTS;

PLANTS (BOTANY);

EMBRYOPHYTA; EUKARYOTA; NICOTIANA TABACUM; TOBACCO MOSAIC VIRUS; VECTORS;

GREEN FLUORESCENT PROTEIN; PHOTOPROTEIN; PLANT VIRUS MOVEMENT PROTEIN; RECOMBINANT DNA; VIRUS DNA; VIRUS PROTEIN;

ARTICLE; GENE VECTOR; GENETICS; METABOLISM; MOVEMENT (PHYSIOLOGY); MUTAGENESIS; PHYSIOLOGY; PLANT LEAF; SENSITIVITY AND SPECIFICITY; TOBACCO; TOBACCO MOSAIC VIRUS; VIROLOGY;

DNA, RECOMBINANT; DNA, VIRAL; GENETIC VECTORS; GREEN FLUORESCENT PROTEINS; LUMINESCENT PROTEINS; MOVEMENT; MUTAGENESIS; PLANT LEAVES; PLANT VIRAL MOVEMENT PROTEINS; SENSITIVITY AND SPECIFICITY; TOBACCO; TOBACCO MOSAIC VIRUS; VIRAL PROTEINS;

EID: 0036078131     PISSN: 09607412     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-313X.2002.01308.x     Document Type: Article

References (28)

1. The amount of movement protein produced in transgenic plants influences the establishment, local movement, and systemic spread of infection by movement protein-deficient tobacco mosaic virus
2. Recombinant tobacco mosaic virus movement protein is an RNA-binding, alpha-helical membrane protein
3. Cell-to-cell and long-distance transport of viruses in plants
4. Tobamovirus isolation and RNA extraction
5. DNA shuffling of a family of genes from diverse species accelerates directed evolution
6. Tobamovirus-plant interactions
7. Second-site reversion of a dysfunctional mutation in a conserved region of the tobacco mosaic tobamovirus movement protein
8. Transgenic plants as factories for biopharmaceuticals
9. Mapping of the tobacco mosaic virus movement protein and coat protein subgenomic RNA promoters in vivo
10. Recombinant PCR
11. Cytoplasmic inhibition of carotenoid biosynthesis with virus-derived RNA
12. Functional integration of non-native carotenoids into chloroplasts by viral-derived expression of capsanthin-capsorubin synthase in Nicotiana benthamiana
13. Plant viruses
14. Role of microtubules in the intracellular distribution of tobacco mosaic virus movement protein
15. Applications of DNA shuffling to pharmaceuticals and vaccines
16. Breeding of retroviruses by DNA shuffling for improved stability and processing yields
17. Interviral homologies of the 30K proteins of tobamoviruses
18. Evolutionary related Sindbis-like plant viruses maintain different levels of population diversity in a common host
19. Heterologous sequences greatly affect foreign gene expression in tobacco mosaic virus-based vectors
20. Packaging of recombinant RNA molecules into pseudovirus particles directed by the origin-of-assembly sequence from tobacco mosaic virus RNA
21. Molecular breeding of viruses
22. Rapid evolution of a protein in vitro by DNA shuffling
23. A novel strategy for the expression of foreign genes from plant virus vectors
24. Tobacco mosaic virus and the virescence of biotechnology
25. Movement protein of tobacco mosaic virus modifies plasmodesmatal size exclusion limit
26. Evolutionary aspects of recombination in RNA viruses
27. An extended secondary structure model for the TMV assembly origin, and its correlation with protection studies and an assembly defective mutant