The International Symposium on regulatory testing and animal welfare: Recommendations on best scientific practices for safety evaluation using nonrodent species

ILAR Journal

Volumn 43, Issue SUPPL., 2002, Pages

  Weekley, L Bruce ^a   Guitin, Pierre ^a   Chamberland, Guy ^a  

^a MERCK RESEARCH LABORATORIES   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ACUTE TOXICITY; ANIMAL CARE; ANIMAL USE; ARTICLE; CONTROLLED STUDY; EVALUATION; EXPERIMENTAL ANIMAL; EXPERIMENTAL ANIMAL WELFARE; GOOD LABORATORY PRACTICE; NONHUMAN; PRACTICE GUIDELINE; SPECIES; SYMPOSIUM; TOXICITY TESTING; TOXICOLOGY;

ANIMALIA;

EID: 0036049685     PISSN: 10842020     EISSN: None     Source Type: Journal    
DOI: 10.1093/ilar.43.suppl_1.s118     Document Type: Article

References (22)

1. CCAC guidelines on choosing an appropriate endpoint in experiments using animals for research, teaching and testing
2. European convention for the protection of vertebrate animals used for experimental and other scientific purposes (ETS123)
3. Note for guidance on the pre-clinical evaluation of anticancer medicinal products
4. Note for guidance on repeated dose toxicity
5. Regulatory considerations for preclinical development of anti-cancer drugs
6. A good practice guide to the administration of substances and removal of blood, including routes and volumes
7. The use of dogs as second species in regulatory testing of pesticides. I. Interspecies comparison
8. Guideline limit volumes for dosing animals in the pre-clinical stage of safety evaluation
9. Guideline limit volumes for dosing animals in the pre-clinical stage of safety evaluation
10. Discomfort and distress in rodents during chronic studies
11. The application of toxicokinetic data to dosage selection in toxicology studies
12. Refining procedures for the administration of substances
13. Guidance document on the Recognition, Assessment, and Use of Clinical Signs as Humane Endpoints for Experimental Animals Used in Safety Evaluation
14. The predictivity of the toxicity of pharmaceuticals in human from animal data-An interim assessment
15. The use of the dog in toxicity tests on pharmaceutical compounds
16. Social enhancement for adult nonhuman primates in research laboratories: A review
17. The Principles of Humane Experimental Technique
18. The use of dogs as second species in regulatory testing of pesticides. II: Subacute, subchronic and chronic studies in the dog
19. Humane endpoints for laboratory animals used in toxicity testing
20. Defining the moribund condition as an experimental endpoint for animal research
21. Humane endpoints and cancer research
22. Predictive value of animal studies in toxicology