Sensitivity of human cancer cells to the new anticancer Ribo-nucleoside TAS-106 is correlated with expression of uridine-cytidine kinase 2

Japanese Journal of Cancer Research

Volumn 93, Issue 7, 2002, Pages 825-833

  Shimamoto, Yuji ^a   Koizumi, Katsuhisa ^a   Okabe, Hiroyuki ^a   Kazuno, Hiromi ^a   Murakami, Yuko ^a   Nakagawa, Fumio ^a   Matsuda, Akira ^b   Sasaki, Takuma ^c   Fukushima, Masakazu ^a  

^a TAIHO PHARMACEUTICAL CO LTD   (Japan)

^b HOKKAIDO UNIVERSITY   (Japan)

^c KANAZAWA UNIVERSITY   (Japan)

Author keywords

Anticancer ribo nucleoside; TAS 106; Uridine cytidine kinase 1; Uridine cytidine kinase 2

Indexed keywords

1 (3 C ETHYNYLRIBOPENTOFURANOSYL)CYTOSINE; 1-(3-C-ETHYNYLRIBOPENTOFURANOSYL)CYTOSINE; ANTINEOPLASTIC AGENT; CYTIDINE; CYTIDYLATE KINASE; DRUG DERIVATIVE; MESSENGER RNA; NUCLEOSIDE MONOPHOSPHATE KINASE; URIDINE KINASE; 1 (3 C ETHYNYL BETA DEXTRO RIBOPENTOFURANOSYL) CYTOSINE; 3' ETHYNYLCYTIDINE; RIBONUCLEOSIDE DERIVATIVE; UNCLASSIFIED DRUG;

ARTICLE; BIOLOGICAL MODEL; CELL CULTURE; CYTOSOL; HUMAN; METABOLISM; PHOSPHORYLATION; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; WESTERN BLOTTING; CANCER CELL; CANCER CELL CULTURE; CANCER TISSUE; CONTROLLED STUDY; CORRELATION FUNCTION; DRUG CYTOTOXICITY; DRUG SELECTIVITY; DRUG SENSITIVITY; ENZYME ACTIVITY; ENZYME PHOSPHORYLATION; HUMAN CELL; HUMAN TISSUE; NUCLEOTIDE SEQUENCE; PANCREAS TUMOR; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN EXPRESSION;

ANTINEOPLASTIC AGENTS; BLOTTING, WESTERN; CYTIDINE; CYTOSOL; HUMANS; MODELS, BIOLOGICAL; NUCLEOSIDE-PHOSPHATE KINASE; PHOSPHORYLATION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; TUMOR CELLS, CULTURED; URIDINE KINASE;

EID: 0036049659     PISSN: 09105050     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1349-7006.2002.tb01325.x     Document Type: Article

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