Risk factors for periodontitis in children and young persons

Periodontology 2000

Volumn 29, Issue 1, 2002, Pages 207-222

  Albandar, Jasim M ^a   Rams, Thomas E ^a  

^a NONE

Author keywords

[No Author keywords available]

Indexed keywords

ADOLESCENT; ADULT; AGE; CHILD; CHRONIC DISEASE; CLASSIFICATION; DENTAL CARE; ETHNIC GROUP; FEMALE; GENETICS; GRAM NEGATIVE INFECTION; HERPES VIRUS INFECTION; HUMAN; IMMUNOLOGY; MALE; MOUTH HYGIENE; PERIODONTITIS; RACE; REVIEW; RISK FACTOR; SEX DIFFERENCE; SMOKING; SOCIAL CLASS; STATISTICS; TOOTH PLAQUE; UTILIZATION REVIEW;

ADOLESCENT; ADULT; AGE FACTORS; CHILD; CHRONIC DISEASE; CONTINENTAL POPULATION GROUPS; DENTAL CARE; DENTAL PLAQUE; ETHNIC GROUPS; FEMALE; GRAM-NEGATIVE BACTERIAL INFECTIONS; HERPESVIRIDAE INFECTIONS; HUMANS; MALE; ORAL HYGIENE; PERIODONTITIS; PERIODONTITIS, JUVENILE; RISK FACTORS; SEX FACTORS; SMOKING; SOCIAL CLASS;

EID: 0036048761     PISSN: 09066713     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1600-0757.2002.290110.x     Document Type: Article

References (176)

1. Aass AM, Albandar JM, Aasenden R, Tollefsen T, Gjermo P. Variation in prevalence of radiographic alveolar bone loss in subgroups of 14-year-old schoolchildren in Oslo. J Clin Periodontol 1988: 15: 130-133.
2. Agarwal S, Suzuki JB, Piesco NP, Aichelmann-Reidy MB. Neutrophil function in juvenile periodontitis: induction of adherence. Oral Microbiol Immunol 1994: 9: 262-271.
3. Albandar JM. Prevalence of incipient radiographic periodontal lesions in relation to ethnic background and dental care provisions in young adults. J Clin Periodontol 1989: 16: 625-629.
4. Albandar JM, Buischi YA, Barbosa MF. Destructive forms of periodontal disease in adolescents. A 3-year longitudinal study. J Periodontol 1991: 62: 370-376.
5. Albandar JM. Juvenile periodontitis - pattern of progression and relationship to clinical periodontal parameters. Community Dent Oral Epidemiol 1993: 21: 185-189.
6. Albandar JM, Buischi YAP, Mayer MPA, Axelsson P. Long-term effect of two preventive programs on the incidence of plaque and gingivitis in adolescents. J Periodontol 1994: 65: 605-610.
7. Albandar JM, Buischi YAP, Axelsson P. Caries lesions and dental restorations as predisposing factors in the progression of periodontal diseases in adolescents. J Periodontol 1995: 66: 249-254.
8. Albandar JM, Buischi YAP, Oliveira LB, Axelsson P. Lack of effect of oral hygiene training on periodontal disease progression during 3 years in adolescents. J Periodontol 1995: 66: 255-260.
9. Albandar JM, Brown LJ, Brunelle JA, Löe H. Gingival state and dental calculus in early-onset periodontitis. J Periodontol 1996: 67: 953-959.
10. Albandar JM, Brown LJ, Genco RJ, Löe H. Clinical classification of early-onset periodontitis in adolescents and young adults. J Periodontol 1997: 68: 545-555.
11. Albandar JM, Brown LJ, Löe H. Clinical features of early-onset periodontitis. J Am Dent Assoc 1997: 128: 1393-1399.
12. Albandar JM, Brown LJ, Löe H. Putative periodontal pathogens in subgingival plaque of young adults with and without early-onset periodontitis. J Periodontol 1997: 68: 973-981.
13. Albandar JM, Kingman A, Brown LJ, Löe H. Gingival inflammation and subgingival calculus as determinants of disease progression in early-onset periodontitis. J Clin Periodontol 1998: 25: 231-237.
14. Albandar JM, Brunelle JA, Kingman A. Destructive periodontal disease in adults 30 years of age and older in the United States, 1988-1994. J Periodontol 1999: 70: 13-29.
15. Albandar JM, Streckfus CF, Adesanya MR, Winn DM. Cigar, pipe and cigarette smoking as risk factors for periodontal disease and tooth loss. J Periodontol 2000: 71: 1874-1881.
16. Albandar JM, DeNardin AM, Adesanya MR, Diehl SR, Winn M. Associations between serum antibody levels to periodontal pathogens and early-onset periodontitis. J Periodontol 2001: 72: 1463-1469.
17. Albandar JM. Periodontal diseases in North America. Periodontol 2000 2002: 29: 31-69
18. Albandar JM, Muranga MB, Rams TE. Prevalence of aggressive periodontitis in school attendees in Uganda. J Clin Periodontol 2002: 29: in press.
19. Albandar JM, DeNardin AM, Adesanya MR, Winn M, Diehl SR. Associations of serum concentrations of IgG, IgA, IgM and interleukin-1β with early-onset periodontitis classification and race. J Clin Periodontol 2002: 29: 421-426
20. Albandar JM. Global risk factors and risk indicators for periodontal diseases. Periodontol 2000 2002: 29: 177-206
21. Albandar JM, Tinoco EMB. Global epidemiology of periodontal diseases in children and young persons. Periodontol 2000 2002: 29: 153-176
22. Altman LC, Page RC, Vandesteen GE, Dixon LI, Bradford C. Abnormalities of leukocyte chemotaxis in patients with various forms of periodontitis. J Periodontal Res 1985: 20: 553-563.
23. Armitage GC. Development of a classification system for periodontal diseases and conditions. Ann Periodontol 1999: 4: 1-6.
24. Armitage GC, Wu Y, Wang HY, Sorrell J, di Giovine FS, Duff GW. Low prevalence of a periodontitis-associated interleukin-1 composite genotype in individuals of Chinese heritage. J Periodontol 2000: 71: 164-171.
25. Axelsson P, Lindhe J. The effect of a preventive programme on dental plaque, gingivitis and caries in schoolchildren. Results after one and two years. J Clin Periodontol 1974: 1: 126-138.
26. Axelsson P, Lindhe J. Effect of controlled oral hygiene procedures on caries and periodontal disease in adults. J Clin Periodontol 1978: 5: 133-151.
27. Axelsson P, Lindhe J, Nyström B. On the prevention of caries and periodontal disease. Results of a 15-year longitudinal study in adults. J Clin Periodontol 1991: 18: 182-189.
28. Baab DA, Page RC, Morton T. Studies of a family manifesting premature exfoliation of deciduous teeth. J Periodontol 1985: 56: 403-409.
29. Baer PN. The case of periodontosis as a clinical entity. J Periodontol 1971: 42: 516-519.
30. Baker PJ, Wilson ME. Opsonic IgG antibody against Actinobacillus actinomycetemcomitans in localized juvenile periodontitis. Oral Microbiol Immunol 1989: 4: 98-105.
31. Benjamin SD, Baer PN. Familial patterns of advanced alveolar bone loss in adolescents (periodontosis). Periodontics 1967: 5: 82-88.
32. Bial JJ, Mellonig JT. Radiographic evaluation of juvenile periodontitis (periodontosis). J Periodontol 1987: 58: 321-326.
33. Blix IJ, Hars R, Preys HR, Helgeland K. Entrance of Actinobacillus actinomycetemcomitans into Hep-2 cells in vitro. J Periodontol 1992: 63: 723-728.
34. Boström L, Linder LE, Bergström J. Clinical expression of TNF-α in smoking-associated periodontal disease. J Clin Periodontol 1998: 25: 767-773.
35. Boström L, Linder LE, Bergström J. Smoking and crevicular fluid levels of IL-6 and TNF-α in periodontal disease. J Clin Periodontol 1999: 26: 352-357.
36. Boughman JA, Beaty TH, Yang P, Goodman SB, Wooten RK, Suzuki JB. Problems of genetic model testing in early onset periodontitis. J Periodontol 1988: 59: 332-337.
37. Boughman JA, Astemborski JA, Suzuki JB. Phenotypic assessment of early onset periodontitis in sibships. J Clin Periodontol 1992: 19: 233-239.
38. Brown LJ, Albandar JM, Brunelle JA, Löe H. Early-onset periodontitis: progression of attachment loss during 6 years. J Periodontol 1996: 67: 968-975.
39. Bueno LC, Mayer MP, DiRienzo JM. Relationship between conversion of localized juvenile periodontitis-susceptible children from health to disease and Actinobacillus actinomycetemcomitans leukotoxin promoter structure. J Periodontol 1998: 69: 998-1007.
40. Butler JH. A familial pattern of juvenile periodontitis (periodontosis). J Periodontol 1969: 40: 115-118.
41. Califano JV, Gunsolley JC, Schenkein HA, Tew JG. A comparison of IgG antibody reactive with Bacteroides forsythus and Porphyromonas gingivalis in adult and early-onset periodontitis. J Periodontol 1997: 68: 734-738.
42. Califano JV, Schifferle RE, Gunsolley JC, Best AM, Schenkein HA, Tew JG. Antibody reactive with Porphyromonas gingivalis serotypes K1-6 in adult and generalized early-onset periodontitis. J Periodontol 1999: 70: 730-735.
43. Centers for Disease Control and Prevention. Tobacco use among high school students - United States, 1997. MMWR Morb Mortal Wkly Rep 1998: 47: 229-233.
44. Cichon P, Crawford L, Grimm WD. Early-onset periodontitis associated with Down's syndrome: clinical interventional study. Ann Periodontol 1998: 3: 370-380.
45. Clerehugh V, Lennon MA. A two-year longitudinal study of early periodontitis in 14-to 16-year-old schoolchildren. Community Dent Health 1986: 3: 135-141.
46. Clerehugh V, Seymour GJ, Bird PS, Cullinan M, Drucker DB, Worthington HV. The detection of Actinobacillus actinomycetemcomitans, Porphyromonas gingivalis and Prevotella intermedia using an ELISA in an adolescent population with early periodontitis. J Clin Periodontol 1997: 24: 57-64.
47. Coccia CT, McDonald RE, Mitchell DF. Papillon-Lefevre syndrome: precocious periodontosis with palmar-plantar hyperkeratosis. J Periodontol 1966: 37: 408-414.
48. Consensus report: Chronic periodontitis. Ann Periodontol 1999: 4: 38.
49. Consensus report: Aggressive periodontitis. Ann Periodontol 1999: 4: 53.
50. Consensus report: Periodontitis as a manifestation of systemic diseases. Ann Periodontol 1999: 4: 64.
51. Consensus report Necrotizing periodontal diseases. Ann Periodontol 1999: 4: 78.
52. Contreras A, Slots J. Mammalian viruses in human periodontitis. Oral Microbiol Immunol 1996: 11: 381-386.
53. Contreras A, Falkler WA Jr, Enwonwu CO, Idigbe EO, Savage KO, Afolabi MB, Onwujekwe D, Rams TE, Slots J. Human Herpesviridae in acute necrotizing ulcerative gingivitis in children in Nigeria. Oral Microbiol Immunol 1997: 12: 259-265.
54. Contreras A, Slots J. Active cytomegalovirus infection in human periodontitis. Oral Microbiol Immunol 1998: 13: 225-230.
55. Contreras A, Umeda M, Chen C, Bakker I, Morrison JL, Slots J. Relationship between herpes viruses and adult periodontitis and periodontopathic bacteria. J Periodontol 1999: 70: 478-484.
56. Contreras A, Rusitanonta T, Chen C, Wagner WG, Michalowicz BS, Slots J. Frequency of 530-bp deletion in Actinobacillus actinomycetemcomitans leukotoxin promoter region. Oral Microbiol Immunol 2000: 15: 338-340.
57. Daniel MA, McDonald G, Offenbacher S, Van Dyke TE. Defective chemotaxis and calcium response in localized juvenile periodontitis neutrophils. J Periodontol 1993: 64: 617-621.
58. Delcourt-Debruyne EM, Boutigny HR, Hildebrand HF. Features of severe periodontal disease in a teenager with Chediak-Higashi syndrome. J Periodontol 2000: 71: 816-824.
59. Diehl SR, Wang Y, Brooks CN, Burmeister JA, Califano JV, Wang S, Schenkein HA. Linkage disequilibrium of interleukin-1 genetic polymorphisms with early-onset periodontitis. J Periodontol 1999: 70: 418-430.
60. DiRienzo JM, Slots J. Genetic approach to the study of epidemiology and pathogenesis of Actinobacillus actinomycetemcomitans in localized juvenile periodontitis. Arch Oral Biol 1990: 35 (Suppl.): 79S-84S.
61. DiRienzo JM, Slots J, Sixou M, Sol MA, Harmon R, McKay TL. Specific genetic variants of Actinobacillus actinomycetemcomitans correlate with disease and health in a regional population of families with localized juvenile periodontitis. Infect Immun 1994: 62: 3058-3065.
62. Dodd CL, Winkler JR, Heinic GS, Daniels TE, Yee K, Greenspan D. Cytomegalovirus infection presenting as acute periodontal infection in a patient infected with the human immunodeficiency virus. J Clin Periodontol 1993: 20: 282-285.
63. Drury TF, Garcia I, Adesanya M. Socioeconomic disparities in adult oral health in the United States. Ann N Y Acad Sci 1999: 896: 322-324.
64. Fives-Taylor PM, Meyer DH, Mintz KP, Brissette C. Virulence factors of Actinobacillus actinomycetemcomitans. Periodontol 2000 1999: 20: 136-167.
65. Genco RJ, Zambon JJ, Murray PA. Serum and gingival fluid antibodies as adjuncts in the diagnosis of Actinobacillus actinomycetemcomitans-associated periodontal disease. J Periodontol 1985: 56: 41-50.
66. Genco RJ, Christersson LA, Zambon JJ. Juvenile periodontitis. Int Dent J 1986: 36: 168-176.
67. Gjermo P, Bellini HT, Santos VP, Martins JG, Ferracyoli JR. Prevalence of bone loss in a group of Brazilian teenagers assessed on bite-wing radiographs. J Clin Periodontol 1984: 11: 104-113.
68. Gunsolley JC, Califano JV, Koertge TE, Burmeister JA, Cooper LC, Schenkein HA. Longitudinal assessment of early onset periodontitis. J Periodontol 1995: 66: 321-328.
69. Gunsolley JC, Pandey JP, Quinn SM, Tew J, Schenkein HA. The effect of race, smoking and immunoglobulin allotypes on IgG subclass concentrations. J Periodontal Res 1997: 32: 381-387.
70. Gwinn MR, Sharma A, De Nardin E. Single nucleotide polymorphism of the N-formyl peptide receptor in localized juvenile periodontitis. J Periodontol 1999: 70: 1194-1201.
71. Haffajee AD, Socransky SS. Microbial etiological agents of destructive periodontal diseases. Periodontol 2000 1994: 5: 78-111.
72. Han NM, Xiao XR, Zhang LS, Ri XQ, Zhang JZ, Tong YH, Yang MR, Xiao ZR. Bacteriological study of juvenile periodontitis in China. J Periodontal Res 1991: 26: 409-414.
73. Hanioka T, Tanaka M, Ojima M, Takaya K, Matsumori Y, Shizukuishi S. Oxygen sufficiency in the gingiva of smokers and non-smokers with periodontal disease. J Periodontol 2000: 71: 1846-1851.
74. Hanookai D, Nowzari H, Contreras A, Morrison JL, Slots J. Herpesviruses and periodontopathic bacteria in Trisomy 21 periodontitis. J Periodontol 2000: 71: 376-384.
75. Hart TC, Marazita ML, Schenkein HA, Brooks CN, Gunsolley JG, Diehl SR. No female preponderance in juvenile periodontitis after correction for ascertainment bias. J Periodontol 1991: 62: 745-749.
76. Hart TC, Hart PS, Bowden DW, Michalec MD, Callison SA, Walker SJ, Zhang Y, Firatli E. Mutations of the cathepsin C gene are responsible for Papillon-Lefevre syndrome. J Med Genet 1999: 36: 881-887.
77. Hashim R, Thomson WM, Pack AR. Smoking in adolescence as a predictor of early loss of periodontal attachment Community Dent Oral Epldemiol 2001: 29: 130-135.
78. Haubek D, Poulsen K, Westergaard I, Dahlén G, Kilian M. Highly toxic done of Actinobacillus actinomycetemcomitans in geographically widespread cases of juvenile periodontitis in adolescents of African origin. J Clin Microbiol 1996: 34: 1576-1578.
79. Haubek D, Ennibi OK, Poulsen K, Poulsen S, Benzarti N, Kilian M. Early-onset periodontitis in Morocco is associated with the highly leukotoxic clone of Actinobacillus actinomycetemcomitans. J Dent Res 2001: 80: 1580-1583.
80. Hennig BJ, Parkhill JM, Chapple IL, Heasman PA, Taylor JJ. Association of a vitamin D receptor gene polymorphism with localized early-onset periodontal diseases. J Periodontol 1999: 70: 1032-1038.
81. Hennig BJ, Parkhill JM, Chapple IL, Heasman PA, Taylor JJ. Dinucleotide repeat polymorphism in the interleukin-10 gene promoter (IL-10.G) and genetic susceptibility to early-onset periodontal disease. Genes Immun 2000: 1: 402-404.
82. Hodge PJ, Teague PW, Wright AF, Kinane DF. Clinical and genetic analysis of a large North European Caucasian family affected by early-onset periodontitis. J Dent Res 2000: 79: 857-863.
83. Holmstrup P, Westegaard J. HIV-associated periodontal diseases. In: Lang N, Karring T. Proceedings of the First European Workshop on Periodontology 1994: 439-461.
84. Holt SC, Kesavalu L, Walker S, Genco CA. Virulence factors of Porphyromonas gingivalis. Periodontol 2000 1999: 20: 168-238.
85. Hørmand I, Frandsen A. Juvenile periodontitis - localization of bone loss in relation to age, sex and teeth. J Clin Periodontol 1979: 6: 407-416.
86. Johnston LD, Bachman JG, O'Malley PM. Monitoring the future: questionnaire responses from the nation's high school seniors, 1995. Ann Arbor. Michigan: Survey Research Center. Institute for Social Research. University of Michigan, 1997.
87. Jorgenson RJ, Levin LS, Hutcherson ST, Salinas CF. Periodontosis in sibs. Oral Surg 1975: 39: 396-402.
88. Kamma JJ, Lygidakis NA, Nakou M. Subgingival microflora and treatment in prepubertal periodontitis associated with chronic idiopathic neutropenia. J Clin Periodontol 1998: 25: 759-765.
89. Kinane DF, Cullen CF, Johnston FA, Evans CW. Neutrophil chemotactic behaviour in patients with early-onset forms of periodontitis (II). Assessment using the under agarose technique. J Clin Periodontol 1989: 16: 247-251.
90. Kinane DF, Hodge P, Eskdale J, Ellis R, Gallagher G. Analysis of genetic polymorphisms at the interleukin-10 and tumor necrosis factor loci in early-onset periodontitis. J Periodontal Res 1999: 34: 379-386.
91. Kinane DF, Mooney J, Ebersole JL. Humoral immune response to Actinobacillus actinomycetemcomitans and Porphyromonas gingivalis in periodontal disease. Periodontol 2000 1999: 20: 289-340.
92. Kinane DF, Chestnutt IG. Smoking and periodontal disease. Crit Rev Oral Biol Med 2000: 11: 356-365.
93. Kinane DF, Podmore M, Ebersole J. Etiopathogenesis of periodontitis in children and adolescents. Periodontol 2000 2001: 26: 54-91.
94. Kornman KS, Crane A, Wang HY, di Giovine FS, Newman MG, Pirk FW, Wilson TG Jr, Higginbottom FL, Duff GW. The interleukin-1 genotype as a severity factor in adult periodontal disease. J Clin Periodontol 1997: 24: 72-77.
95. Kronauer E, Borsa G, Lang NP. Prevalence of incipient juvenile periodontitis at age 16 years in Switzerland. J Clin Periodontol 1986: 13: 103-108.
96. Lindhe J, Hamp SE, Löe H. Plaque induced periodontal disease in beagle dogs. A 4-year clinical, roentgenographical and histometrical study. J Periodontal Res 1975: 10: 243-255.
97. Locker D, Clarke M, Murray H. Oral health status of Canadian-born and immigrant adolescents in North York. Ontario Community Dent Oral Epidemiol 1998: 26: 177-181.
98. Löe H, Theilade E, Jensen SB. Experimental gingivitis in man. J Periodontol 1965: 36: 177-187.
99. Löe H, Brown LJ. Early onset periodontitis in the United States of America. J Periodontol 1991: 62: 608-616.
100. Loesche WJ. The role of spirochetes in periodontal disease. Adv Dent Res 1988: 2: 275-283.
101. Long JC, Nance WE, Waring P, Burmeister JA, Ranney RR. Early onset periodontitis: a comparison and evaluation of two proposed modes of inheritance. Genet Epidemiol 1987: 4: 13-24.
102. Lopez NJ, Rios V, Pareja MA, Fernandez O. Prevalence of juvenile periodontitis in Chile. J Clin Periodontol 1991: 18: 529-533.
103. Lopez NJ. Clinical, laboratory, and immunological studies of a family with a high prevalence of generalized prepubertal and juvenile periodontitis. J Periodontol 1992: 63: 457-168.
104. Lopez NJ, Mellado JC, Giglio MS, Leighton GX. Occurrence of certain bacterial species and morphotypes in juvenile periodontitis in Chile. J Periodontol 1995: 66: 559-567.
105. Lopez NJ, Mellado JC, Leighton GX. Occurrence of Actinobacillus actinomycetemcomitans, Porphyromonas gingivalis and Prevotella intermedia in juvenile periodontitis. J Clin Periodontol 1996: 23: 101-105.
106. Lopez R, Fernandez O, Jara G, Baelum V. Epidemiology of clinical attachment loss in Chilean adolescents. J Periodontol 2001: 72: 1666-1672.
107. Machuca G, Rosales I, Lacalle JR, Machuca C, Bullon P. Effect of cigarette smoking on periodontal status of healthy young adults. J Periodontol 2000: 71: 73-78.
108. Mandell RL, Ebersole JL, Socransky SS. Clinical immunologic and microbiologic features of active disease sites in juvenile periodontitis. J Clin Periodontol 1987: 14: 534-540.
109. Manson JD, Lehner T. Clinical features of juvenile periodontitis (periodontosis). J Periodontol 1974: 45: 636-640.
110. Marazita ML, Burmeister JA, Gunsolley JC, Koertge TE, Lake K, Schenkein HA. Evidence for autosomal dominant inheritance and race-specific heterogeneity in early-onset periodontitis. J Periodontol 1994: 65: 623-630.
111. Mardirossian A, Contreras A, Navazesh M, Nowzari H, Slots J. Herpesviruses 6, 7 and 8 in HIV-and non-HIV-associated periodontitis. J Periodontal Res 2000: 35: 278-284.
112. Melnick M, Shields ED, Bixler D. Periodontosis: a phenotypic and genetic analysis. Oral Surg 1976: 42: 32-41.
113. Melvin WL, Sandifer JB, Gray JL. The prevalence and sex ratio of juvenile periodontitis in a young racially mixed population. J Periodontol 1991: 62: 330-334.
114. Meyer DH, Sreenivasan PK, Fives-Taylor PM. Evidence for invasion of a human oral cell line by Actinobacillus actinomycetemcomitans. Infect Immun 1991: 59: 2719-2726.
115. Michalowicz BS, Aeppli D, Virag JG, Klump DG, Hinrichs JE, Segal NL, Bouchant TJ, Pihlstrom BL. Periodontal findings in adult twins. J Periodontol 1991: 62: 293-299.
116. Michalowicz BS. Genetic and heritable risk factors in periodontal disease. J Periodontol 1994: 65: 479-488.
117. Michalowicz BS, Diehl SR, Gunsolley JC, Sparks BS, Brooks CN, Koertge TE, Califano JV, Burmeister JA, Schenkein HA. Evidence of a substantial genetic basis for risk of adult periodontitis. J Periodontol 2000: 71: 1699-1707.
118. Modeer T, Barr M, Dahllof G. Periodontal disease in children with Down's syndrome. Scand J Dent Res 1990: 98: 228-234.
119. Mooney J, Hodge PJ, Kinane DF. Humoral immune response in early-onset periodontitis: influence of smoking. J Periodontal Res 2001: 36: 227-232.
120. Moore WE, Holdeman LV, Cato EP, Smibert RM, Burmeister JA, Palcanis KG, Ranney RR. Comparative bacteriology of juvenile periodontitis. Infect Immun 1985: 48: 507-519.
121. Moore WEC, Moore LVH. The bacteria of periodontal diseases. Periodontol 2000 1994: 5: 66-77.
122. Mullally BH, Breen B, Linden GJ. Smoking and patterns of bone loss in early-onset periodontitis. J Periodontol 1999: 70: 394-401.
123. Nassar MM, Afifi O, Deprez RD. The prevalence of localized juvenile periodontitis in Saudi subjects. J Periodontol 1994: 65: 698-701.
124. Neely AL. Prevalence of juvenile periodontitis in a circumpubertal population. J Clin Periodontol 1992: 19: 367-372.
125. Newacheck PW, Hughes DC, Hung YY, Wong S, Stoddard JJ. The unmet health needs of America's children. Pediatrics 2000: 105: 989-997.
126. Niederman R, Westernoff T, Lee C, Mark LL, Kawashima N, Ullman-Culler M, Dewhirst FE, Paster BJ, Wagner DD, Mayadas T, Hynes RO, Stashenko P. Infection-mediated early-onset periodontal disease in P/E-selectin-deficient mice. J Clin Periodontol 2001: 28: 569-575.
127. Niemienen K, Kari K, Saxen L. Specific antibodies against Actinobacillus actinomycetemcomitans in serum and saliva of patients with advanced periodontitis. Scand J Dent Res 1993: 101: 196-201.
128. Novak MJ. Necrotizing ulcerative periodontitis. Ann Periodontol 1999: 4: 74-77.
129. Page RC, Sims TJ, Geissler F, Altman LC, Baab DA. Defective neutrophil and monocyte motility in patients with early onset periodontitis. Infect Immun 1985: 47: 169-175.
130. Page RC, Beatty P, Waldrop TC. Molecular basis for the functional abnormality in neutrophils from patients with generalized prepubertal periodontitis. J Periodontal Res 1987: 22: 182-183.
131. Parkhill JM, Hennig BJ, Chapple IL, Heasman PA, Taylor JJ. Association of interleukin-1 gene polymorphisms with early-onset periodontitis. J Clin Periodontol 2000: 27: 682-689.
132. Parra B, Slots J. Detection of human viruses in periodontal pockets using polymerase chain reaction. Oral Microbiol Immunol 1996: 11: 289-293.
133. Perry DA, Newman MG. Occurrence of periodontitis in an urban adolescent population. J Periodontol 1990: 61: 185-188.
134. Preus HR, Olsen I, Gjermo P. Bacteriophage infection - a possible mechanism for increased virulence of bacteria associated with rapidly destructive periodontitis. Acta Odontol Scand 1987: 45: 49-54.
135. Prichard JF, Ferguson DM, Windmiller J, Hurt WC. Prepubertal periodontitis affecting the deciduous and permanent dentition in a patient with cyclic neutropenia. A case report and discussion. J Periodontol 1984: 55: 114-122.
136. Quinn SM, Zhang JB, Gunsolley JC, Schenkein JG, Schenkein HA, Tew JG. Influence of smoking and race on immunoglobulin G subclass concentrations in early-onset periodontitis patients. Infect Immun 1996: 64: 2500-2505.
137. Rams TE, Andriolo M, Feik D, Abel SN, McGivern TM, Slots J. Microbiological study of HIV-related periodontitis. J Periodontol 1991: 62: 74-81.
138. Rowland RW. Necrotizing ulcerative gingivitis. Ann Periodontol 1999: 4: 65-73.
139. Sandmeier H, van Winkelhoff AJ, Bar K, Ankli E, Maeder M, Meyer J. Temperate bacteriophages are common among Actinobacillus actinomycetemcomitans isolates from periodontal pockets. J Periodontal Res 1995: 30: 418-425.
140. Saxby MS. Juvenile periodontitis: an epidemiological study in the west Midlands of the United Kingdom. J Clin Periodontol 1987: 14: 594-598.
141. Saxén L. Prevalence of juvenile periodontitis in Finland. J Clin Periodontol 1980: 7: 177-186.
142. Saxén L, Nevanlinna HR. Autosomal recessive inheritance of juvenile periodontitis: test of a hypothesis. Clin Genet 1984: 25: 332-335.
143. Sbordone L, Ramaglia L, Bucci E. Generalized juvenile periodontitis: report of a familial case followed for 5 years. J Periodontol 1990: 61: 590-596.
144. Schenkein HA, Best AM, Gunsolley JC. Influence of race and periodontal clinical status on neutrophil chemotactic responses. J Periodontal Res 1991: 26: 272-275.
145. Schenkein HA, Van Dyke TE. Early-onset periodontitis: systemic aspects of etiology and pathogenesis. Periodontol 2000 1994: 6: 7-25.
146. Schenkein HA, Gunsolley JC, Koertge TE, Schenkein JG, Tew JG. Smoking and its effects on early-onset periodontitis. J Am Dent Assoc 1995: 126: 1107-1113.
147. Shapira L, Schlesinger M, Bimstein E. Possible autosomal-dominant inheritance of prepubertal periodontitis in an extended kindred. J Clin Periodontol 1997: 24: 388-393.
148. Shibata K, Warbington ML, Gordon BJ, Kurihara H, Van Dyke TE. Defective calcium influx factor activity in neutrophils from patients with localized juvenile periodontitis. J Periodontol 2000: 71: 797-802.
149. Slots J. The predominant cultivable organisms in juvenile periodontitis. Scand J Dent Res 1976: 84: 1-10.
150. Slots J. Subgingival microflora in periodontal disease. J Clin Periodontol 1979: 6: 351-382.
151. Slots J. Bacterial specificity in adult periodontitis - A summary of recent work. J Clin Periodontol 1986: 13: 912-917.
152. Slots J, Rams TE. Microbiology of periodontal disease. In: Slots J, Taubman M. Contemporary oral microbiology and immunology. St Louis, Mosby 1992: 425-443.
153. Slots J. Actinobacillus actinomycetemcomitans and Porphyromonas gingivalis in periodontal disease: introduction. Periodontol 2000 1999: 20: 7-13.
154. Slots J, Ting M. Actinobacillus actinomycetemcomitans and Porphyromonas gingivalis in human periodontal disease: occurrence and treatment. Periodontol 2000 1999: 20: 82-121.
155. Slots J, Contreras A. Herpesviruses: a unifying causative factor in periodontitis? Oral Microbiol Immunol 2000: 15: 277-280.
156. Spektor MD, Vandesteen GE, Page RC. Clinical studies of one family manifesting rapidly progressive, juvenile and prepubertal periodontitis. J Periodontol 1985: 56: 93-101.
157. Taiwo JO. Effect of social class on the prevalence and severity of necrotising ulcerative gingivitis in Nigerian children. Afr J Med Med Sci 1996: 25: 357-360.
158. Tangada SD, Califano JV, Nakashima K, Quinn SM, Zhang JB, Gunsolley JC, Schenkein HA, Tew JG. The effect of smoking on serum IgG2 reactive with Actinobacillus actinomycetemcomitans in early-onset periodontitis patients. J Periodontol 1997: 68: 842-850.
159. Theilade E. The non-specific theory in microbial etiology of inflammatory periodontal diseases. J Clin Periodontol 1986: 13: 905-911.
160. Ting M, Contreras A, Slots J. Herpesvirus in localized juvenile periodontitis. J Periodontal Res 2000: 35: 17-25.
161. Tinoco EMB, Beldi MI, Loureiro CA, Lana M, Campedelli F, Tinoco NMB, Gjermo P, Preus HR. Localized juvenile periodontitis and Actinobacillus actinomycetemcomitans in a Brazilian population. Eur J Oral Sci 1997: 105: 9-14.
162. Tolo K. Periodontal disease mechanisms in immunocompromised patients. J Clin Periodontol 1991: 18: 431-435.
163. Tomar SL, Asma S. Smoking-attributable periodontitis in the United States: findings from NHANES III. National Health and Nutrition Examination Survey. J Periodontol 2000: 71: 743-751.
164. Tonetti MS. Cigarette smoking and periodontal diseases: etiology and management of disease. Ann Periodontol 1998: 3: 88-101.
165. US Department of Health and Human Services. Preventing tobacco use among young people: a report of the Surgeon General. Atlanta: Centers for Disease Control and Prevention, National Center for Chronic Disease Prevention and Health Promotion, Office on Smoking and Health, 1994.
166. Umeda M, Chen C, Bakker I, Contreras A, Morrison JL, Slots J. Risk indicators for harboring periodontal pathogens. J Periodontol 1998: 69: 1111-1118.
167. Van Dyke TE, Schweinebraten M, Cianciola LL, Offenbacher S, Genco RJ. Neutrophil chemotaxis in families with localized juvenile periodontitis. J Periodontal Res 1985: 20: 503-514.
168. Van Dyke TE, Zinney W, Winkel K, Taufiq A, Offenbacher S, Arnold RR. Neutrophil function in localized juvenile periodontitis. Phagocytosis, superoxide production and specific granule release. J Periodontol 1986: 57: 703-708.
169. van Winkelhoff AJ, Schouten-van Meeteren AY, Baart JA, Vandenbroucke-Grauls CM. Microbiology of destructive periodontal disease in adolescent patients with congenital neutropenia. A report of 3 cases. J Clin Periodontol 2000: 27: 793-798.
170. Wagaiyu EG, Wagaiyu CK. Prevalence of juvenile periodontitis in national youth service trainees. East Afr Med J 1992: 69: 31-33.
171. Waldman HB. More children are unable to get dental care than any other single health service. J Dent Child 1998: 65: 204-208.
172. Waldrop TC, Anderson DC, Hallmon WW, Schmalstieg FC, Jacobs RL. Periodontal manifestations of the heritable mac-1, lfa-1, deficiency syndrome. Clinical, histopathological and molecular characteristics. J Periodontol 1987: 58: 400-416.
173. Waldrop TC, Hallmon WW, Mealey BL. Observations of root surfaces from patients with early-onset periodontitis and leukocyte adhesion deficiency. J Clin Periodontol 1995: 22: 168-178.
174. Walker SJ, Van Dyke TE, Rich S, Kornman KS, di Giovine FS, Hart TC. Genetic polymorphisms of the IL-1α and IL-1α genes in African-American LJP patients and an African-American control population. J Periodontol 2000: 71: 723-728.
175. Zambon JJ, Umemoto T, De Nardin E, Nakazawa F, Christersson LA, Genco RJ. Actinobocillus actinomycetemcomitans in the pathogenesis of human periodontal disease. Adv Dent Res 1988: 2: 269-274.
176. Zhang Y, Lundgren T, Renvert S, Tatakis DN, Firatli E, Uygur C, Hart PS, Gorry MC, Marks JJ, Hart TC. Evidence of a founder effect for four cathepsin C gene mutations in Papillon-Lefevre syndrome patients. J Med Genet 2001: 38: 96-101.