Association of interleukin-1 gene polymorphisms with early-onset periodontitis

Journal of Clinical Periodontology

Volumn 27, Issue 9, 2000, Pages 682-689

  Parkhill, Judith M ^a   Hennig, Branwen J W ^a   Chapple, Iain L C ^b   Heasman, Peter A ^a   Taylor, John J ^a  

^a NEWCASTLE UNIVERSITY   (United Kingdom)

^b UNIVERSITY OF BIRMINGHAM   (United Kingdom)

Author keywords

Early onset periodontitis; Gene polymorphisms; Interleukin 1 receptor antagonist; Interleukin 1

Indexed keywords

DNA; IL1RN PROTEIN, HUMAN; INTERLEUKIN 1; INTERLEUKIN 1 RECEPTOR; INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; PRIMER DNA; SIALOGLYCOPROTEIN;

ADOLESCENT; ADULT; ALLELE; ARTICLE; COMPARATIVE STUDY; DRUG ANTAGONISM; FEMALE; GENETIC POLYMORPHISM; GENETICS; GENOTYPE; HUMAN; MALE; METHODOLOGY; MIDDLE AGED; MOLECULAR GENETICS; NUCLEOTIDE SEQUENCE; PERIODONTITIS; POLYMERASE CHAIN REACTION;

ADOLESCENT; ADULT; ALLELES; BASE SEQUENCE; DNA; DNA PRIMERS; FEMALE; GENOTYPE; HUMANS; INTERLEUKIN 1 RECEPTOR ANTAGONIST PROTEIN; INTERLEUKIN-1; MALE; MIDDLE AGED; MOLECULAR SEQUENCE DATA; PERIODONTITIS; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC; RECEPTORS, INTERLEUKIN-1; SIALOGLYCOPROTEINS;

EID: 0034277122     PISSN: 03036979     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1600-051x.2000.027009682.x     Document Type: Article

References (52)

1. Albandar, J. M., Brown, L. J., Genco, R. J. & Löe, H. (1997) Clinical classification of periodontitis in adolescents and young adults. Journal of Periodontology 68, 545-555.
2. Alexander, M. B. & Damoulis, P. D. (1994) The role of cytokines in the pathogenesis of periodontal disease. Current Opinion in Periodontology 2, 39-53.
3. Balkwill, F. (1993) Cytokines in health and disease. Immunology Today 14, 149-150.
4. Bernzweig, E., Payne, J. B., Reinhardt, R. A., Dyer, J. K. & Patil, K. D. (1998) Nicotine and smokeless tobacco effects on gingival and peripheral blood mononuclear cells. Journal of Clinical Periodontology 25, 246-252.
5. Boughman, J. A., Astemborski, J.A. & Blitzer, M.G. (1990) Early onset periodontal disease: a genetics perspective. Critical Reviews in Oral Biology and Medicine 1, 89-99.
6. Collins, F.S., Guyer, M.S. & Chakravarti, A. (1997) Variations on a theme: Cataloging human DNA sequence variation. Science 278, 1580-1581.
7. Collins, F.S., Patrinos, A., Jordan, E., Chakravarti, A., Gesteland, R. & Walters, L. (1998) New goals for the US Human Genome Project: 1998-2003. Science 282, 682-689.
8. Cox, A., Camp, N.J., Nicklin, M.J.H., Di Giovine, F.S. & Duff, G.W. (1998) An analysis of linkage disequilibrium in the interleukin-1 gene cluster, using a novel grouping method for multiallelic markers. American Journal of Human Genetics 62, 1180-1188.
9. Danis, V. A., Millington, M., Hyland, V. J. & Grennan, D. (1995) Cytokine production by normal human monocytes: inter-subject variation and relationship to an IL-1 receptor antagonist (IL-1Ra) gene polymorphism. Clinical Experimental Immunology, 99, 303-310.
10. Diehl, S.R., Wang Y.F., Brooks C.N., Burmeister J.A., Califano J.V., Wang S.B., Schenkein, H.A. (1999) Linkage disequilibrium of interleukin-1 genetic polymorphisms with early-onset periodontitis. Journal of Periodontology, 70, 418-430.
11. Dinarello, C. A. (1994) The interleukin-1 family: 10 years of discovery. The FASEB Journal 8, 1314-1325.
12. Duff, G. W. (1993) Cytokines and Anti-cytokines. British Journal of Rheumatology 32, 15-20.
13. Duff, G. W. (1998) Molecular genetics of cytokines: Cytokines in chronic inflammatory disease. In: The cytokine handbook, ed. Thompson, A., pp. 21-33. London: Academic Press.
14. Endres, S., Ghorbani, R., Lonnemann, G., Vandermeer, J.W.M. & Dinarello, C.A. (1988) Measurement of immunoreactive interleukin-1β from human mononuclear cells - optimization of recovery, intrasubject consistency, and comparison with interleukin-1-α and tumor necrosis factor. Clinical Immunology and Immunopathology 49, 424-438.
15. Endres, S., Cannon, J.G., Ghorbani, R., Dempsey, R.A., Sisson, S.D., Lonnemann, G., Vandermeer, J.W.M., Wolff, S.M. & Dinarello, C.A. (1989) In vitro production of IL-1-beta, IL-1-alpha, TNF and IL-2 in healthy-subjects - distribution, effect of cyclooxygenase inhibition and evidence of independent gene-regulation. European Journal Of Immunology 19, 2327-2333.
16. Ferris, R.T., Listgarten, M.A., Caton, J.G. (1989). Consensus report and discussion 1. In: Proceedings of the World Workshop in Clinical periodontics, eds. Nevins, M., Becker, W. & Kornman, K., pp23-31. Princeton: American Academy of Periodontology.
17. Galbraith, G.M.P., Steed, R.B., Sanders, J.J. & Pandey, J.P. (1998) Tumor necrosis factor alpha production by oral leukocytes: influence of tumor necrosis factor genotype. Journal of Periodontology 69, 428-433.
18. Genco, R. J., Christersson, L. A. & Zambon, J. J. (1986) Diagnosis and treatment of localised juvenile periodontitis. International Dental Journal 36, 168-176.
19. +3953 allele 2: association with disease status in adult periodontitis. Journal of Clinical Periodontology 25, 781-785.
20. Hart, T. C. (1996) Genetic risk factors for early-onset periodontitis. Journal of Periodontology, 67, 355-366.
21. Hart, T.C. & Kornman, K.S. (1997) Genetic factors in the pathogenesis of periodontitis. Periodontology 2000 14, 202-215.
22. Hennig, B. J. W., Parkhill, J. M., Chapple, I. L. C., Heasman, P. A. & Taylor, J. J. (1999). Association of a Vitamin D receptor gene polymorphism and localised early-onset periodontal diseases. Journal of Periodontology 70, 1032-1038.
23. Hou, L.-T., Liu, C.-M. & Rossomando, E. F. (1995) Crevicular interleukin-1beta in moderate and severe periodontitis patients and the effect of phase 1 periodontal treatment. Journal of Clinical Periodontology 22, 162-167.
24. Hurme, M. & Santtila, S. (1998) IL-1 receptor antagonist (IL-1Ra) plasma levels are coordinately regulated by both IL-1Ra and IL-1 beta genes. European Journal Of Immunology 28, 2598-2602.
25. Ishihara, Y., Nishihara, T., Kuroyanagi, T., Shirozu, N., Yamagishi, E., Ohguchi, M., Koide, M., Ueda, N., Amano, K. & Noguchi, T. (1997) Gingival crevicular interleukin-1 and interleukin-1 receptor antagonist levels in periodontally healthy and diseased sites. Journal of Periodontal Research 32, 524-529.
26. Kjeldsen M., Holmstrup, P., Lindemann, RA. & Bendtzen, K. (1995) Bacterial-stimulated cytokine production of peripheral mononuclear cells from patients of various periodontitis categories. Journal of Periodontology 66, 139-144.
27. Kobayashi, T., Westerdaal, N.A.C., Miyazaki, A., vanderPol, W.L., Suzuki, T., Yoshie, H., Van deWinkel, J.G.J. & Hara, K. (1997) Relevance of immunoglobulin G Fc receptor polymorphism to recurrence of adult periodontitis in Japanese patients. Infection and Immunity 65, 3556-3560.
28. Kornman, K. S., Crane, A., Wang, H.-Y., di Giovine, F. S., Newman, M. G., Pirk, F. W., Wilson Jr., T. G., Higgenbottom, F. L. & Duff, G. W. (1997) The interleukin-1 genotype as a severity factor in adult periodontal disease. Journal of Clinical Periodontology 24, 72-77.
29. Lander, E.S. & Schork, N.J. (1994) Genetic dissection of complex traits. Science 265, 2037-2048.
30. Marazita ML, Burmeister JA, Gunsolley JC, Koertge TE, Lake K, Schenkein HA. (1994) Evidence for autosomal-dominant inheritance and race-specific heterogeneity in early-onset periodontitis. Journal of Periodontology 65, 623-630.
31. Marazita, M. L., Lu, H., Cooper, M. E., Quinn, S. M., Zhang, J.-B., Burmeister, J. A., Califano, J. V., Pandey, J. P., Schenkein, H. A., & Tew, J. G. (1996) Genetic segregation analyses of serum IgG2 levels. American Journal of Human Genetics, 58, 1042-1049.
32. Mattiuz, P. L., Ihde, D. & Piazza, A. (1970). New approaches to the population genetics and aggregation analysis of the HLA system. In: Histocompatibility testing, ed. Terasaki, P.I., pp. 193-205. Copenhagen: Munksgaard.
33. Mehta, C. R. & Patel, N. R. (1986) Algorithm 643 Fexact: a Fortran subroutine for Fisher's exact test on unordered rxc contingency tables. Association of Computing Machinery Transactions of Mathematical Software 12, 154-161.
34. Molvig, J., Baek, L., Christensen, P., Manogue, K.R., Vlassara, H., Platz, P., Nielsen, L.S., Svejgaard, A. & Nerup, J. (1988) Endotoxin-stimulated human monocyte secretion of interleukin-1, tumor necrosis factor-alpha, and prostaglandin-E2 shows stable interindividual differences. Scandinavian Journal of Immunology 27, 705-716.
35. Nicklin, M. J. H., Weith, A. & Duff, G. W. (1994) A physical map of the region encompassing the human interleukin-1α, interleukin-1β, and interleukin-1 receptor antagonist genes. Genomics, 19, 382-384.
36. Novak, M. J. & Novak, K. F. (1996) Early-onset periodontitis. Current Opinion in Periodontology, 3, 45-58.
37. 2 secretion as a determinant of periodontal disease expression. Journal of Periodontology 64, 432-444.
38. Okada, H. & Murakami, S. (1998) Cytokine expression in periodontal health and disease. Critical Reviews in Oral Biology and Medicine 9, 248-266.
39. Page, R. (1991) The role of inflammatory mediators in the pathogenesis of periodontal disease. Journal of Periodontal Research, 26, 230-242.
40. Pociot, F., Molvig, J., Wogensen, L., Worsaae, H. & Nerup, J. (1992) A Taq1 polymorphism in the interleukin-1 beta gene correlates with IL-1β secretion in vitro. European Journal of Clinical Investigation 22, 396-402.
41. Risch, N., Merikangas, K. (1996) The future of genetic studies of complex human diseases. Science 273, 1516-1517.
42. Santtila, S., Savinainen, K., Hurme, M. (1998) Presence of the IL-1RA allele 2 (IL1RN*2) is associated with enhanced IL-1β production in vitro. Scandinavian Journal of Immunology 47,195-198.
43. Sauty, A., Mauel, J., Philippeaux, M. M. & Leuenberger, P. (1994) Cytostatic activity of alveolar macrophages from smokers and non-smokers: role of interleukin-1β, interleukin-6, and tumour necrosis factor-α. American Journal of Respiratory Cell and Molecular Biology 11, 631-637.
44. Schenkein HA. (1994) Genetics of early-on-set periodontal diseases. In: Molecular pathology of periodontal disease, eds. Genco, R., Hamada, S., Lehner, T., McGhee, J. & Mergenhagen, S., pp373-386. Washington: ASM press.
45. Shapira, L., Soskolne, W. A., Sela, M. N., Offenbacher, S. & Barak, V. (1994) The secretion of PGE2, IL-1β, IL-6 and TNF-α by adherent mononuclear cells from early onset periodontitis patients. Journal of Periodontology 65, 139-146.
46. Sobell, J.L, Heston, L.L. & Sommer, S.S. (1992) Delineation of genetic predisposition to multifactorial disease - a general-approach on the threshold of feasibility. Genomics 12, 1-6.
47. Soliman, D. M. & Twigg, H. L. (1992) Cigarette smoking decreases bioactive interleukin-6 secretion by alveolar macrophages. American Journal of Physiology 263, 471-478.
48. Tarlow, J. K., Blakemore, A. I. F., Lennard, A., Solari, R., Hughes, H. N., Steinkasserer, A. & Duff, G. W. (1993) Polymorphism in human IL-1 receptor antagonist gene intron 2 is caused by variable numbers of an 86-bp tandem repeat. Human Genetics 91, 403-404.
49. Tarlow, J. K., Cork, M. J., Clay, F. E., Schmitt-Egenolf, M., Crane, A. M., Stierle, C., Boehncke, W. H., Eierman, T. H., Blakemore, A. I. F., Bleehan, S. S., Sterry, W. & Duff, G. W. (1997) Association between interleukin-1 receptor antagonist gene polymorphism and early and late onset psoriasis. British Journal of Dermatologists 136, 132-148.
50. Weeks, DE, Lathrop, GM. (1995) Polygenic disease - methods for mapping complex disease traits. Trends In Genetics 11, 513-519.
51. Wilton, J. M. A., Bampton, J. L. M. & Griffiths, G. S. (1992) Interleukin-1beta levels in gingival crevicular fluid from adults with previous evidence of destructive periodontitis. Journal of Clinical Periodontology 19, 53-57.
52. Van Dyke, T. E. & Schenkein, H. A. (1996) Research objectives for the study of early-onset periodontitis. A summary of the working groups for the early-onset periodontitis workshop. Journal of Periodontology 67, 279-281.