The mysterious immunoglobulin light chain

Developmental and Comparative Immunology

Volumn 26, Issue 2, 2002, Pages 207-215

  Pilström, Lars ^a  

^a UPPSALA UNIVERSITY   (Sweden)

Author keywords

Evolution; Expression; Immunoglobulin light chains; Variability

Indexed keywords

IMMUNOGLOBULIN LIGHT CHAIN; T LYMPHOCYTE RECEPTOR ALPHA CHAIN;

AMPHIBIA; ANTIGEN BINDING; BIRD; EVOLUTION; FISH; MAMMAL; NONHUMAN; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROTEIN STRUCTURE; REPTILE; REVIEW; SEQUENCE ANALYSIS; SPECIES DIFFERENCE;

CAMELIDAE; CHONDRICHTHYES;

EID: 0036027529     PISSN: 0145305X     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0145-305X(01)00066-0     Document Type: Article

References (68)

1. Immunoglobulins: molecular genetics
2. A new antigen receptor gene family that undergoes rearrangement and extensive somatic diversification in sharks
3. Naturally occuring antibodies devoid of light chains
4. Camel heavy-chain antibodies: diverse germline VHH and specific mechanisms enlarge the antigen-binding repertoire
5. A third light chain gene isotype in Xenopus laevis consists of six distinct VL families and is related to mammalian λ genes
6. Evolution of immunoglobulin light chain genes: analysis of Xenopus IgL isotypes and their contribution to antibody diversity
7. Sequence of C region of L chain from Xenopus laevis Ig
8. Characterization of three isotypes of immunoglobulin light chains and T-cell antigen receptor α in zebrafish
9. A cluster type organization of the loci of the immunogloibulin light chain in Atlantic cod (Gadus morhua L.) and rainbow trout (Oncorhynchus mykiss Walbaum) indicated by nucleotide sequences of cDNA and hybridization analysis
10. A second immunoglobulin isotype in the rainbow trout
11. Shannon information as a measure of amino acid diversity
12. Variability of the immunoglobulin light chain in the Siberian sturgeon, Acipenser baeri
13. A Shannon entropy analysis of immunoglobulin and T cell receptor
14. Attempts to locate complemetarity-determining residues in the variable positions of light and heavy chains
15. Lack of heterogeneity in antihapten antibodies of a phylogenetically primitive shark
16. Structural and functional analysis of spontaneous anti-nitrophenyl antibodies in three cyprinid species: carp (Cyprinus carpio), goldfish (Carassius auratus) and tench (Tinca tinca)
17. Antibody diversity in fish. Isoelectrofocalisation study of individually-purified specific antibodies in three teleost fish species: tench, carp and goldfish
18. Phylogeny of immunoglobulin structure and function. V. Valances and association canstants of teleost antibodies to a haptenic determinant
19. Evolution of antibody structure and effector functions: comparative hemolytic activities of monomeric and tetrameric IgM from rainbow trout, Salmo gairdneri
20. The specificity of Atlantic salmon antibodies made against the fish pathogen Vibrio salmonicida, establishing the surface protein VS-P1 as the dominant antigen
21. Determination of serum antibody affinity distributions using ELISA-based technology
22. Immunization of carp (Cyprinus carpio) with a Vibrio anguillarum bacterin: indications for a common mucosal immune system
23. Proteolytic fragmentation of channel catfish antibodies
24. Structure and function of natural antibodies
25. The repertoire of serum IgM in normal mice is largely independent of external antigenic contact
26. The self-reactive antibody repertoire of normal human serum IgM is acquired in early childhood and remains conserved throughout life
27. Light chain variabe region diversity in Atlantic cod (Gadus morhua L.)
28. Two serotypes of Vibrio salmonicida isolated from diseased cod (Gadus morhua L.); virulence, immunological studies and vaccination experiments
29. Isolation and partial characterization of immunoglobulin from cod (Gadus morhua L.)
30. Humoral immunoglobulins of the white sturgeon, Acipenser transmontanus: partial characterization of and recoginition with monoclonal antibodies
31. Variable region diversity of the Atlantic cod (Gadus morhua L.) immunoglobulin heavy chain
32. Ig-light chain variability in DNP494-KLH immunised sea bass (Dicentrarchus labrax L.): evidence for intramolecular-induced supression
33. Structure and genomic organization of immunoglobulin light chain in the channel catfish. An unusual genomic organizational pattern of segmental genes
34. Structure and genomic organization of a second class of immunoglobulin light chain genes in the channel catfish
35. Different genomic organization and expression of immunoglobulin light-chain isotypes in the rainbow trout
36. Transcriptional enhancers of immunoglobulin light chain genes in Atlantic cod (Gadus morhua)
37. improving the sensitivity of progressives multiple sequence alignment through sequence weighting, position-specific gap penalties and weight matrix choice
38. Diversity of expressed V and J regions of immunoglobulin light chains in Xenopus laevis
39. Generation of immunoglobulin light chain chain gene diversity in Raja erinacea is not associated with somatic rearrangement, an exception to a central paradigm of B cell immunity
40. Immunoglobulin light chain class multiplicity and alternative organizational forms in early vertebrate phylogeny
41. Isolation of a shark immunoglobulin light chain cDNA clone encoding a protein resembling mammalian κ light chains: Implications for the evolution of light chains
42. Complete sequence of a cDNA clone specifying sandbar shark immunoglobulin light chain: gene organisation and implications for the evolution of light chains
43. Genomic organization and sequences of immunoglobulin light chain genes in a primitive vertebrate suggest coevolution of immunoglobulin gene organization
44. Complete nucleotide sequence of primitive vertebrate immunoglobulin light chain genes
45. Ig light chain gene in the Siberian sturgeon (Acipenser baeri). Implications for the evolution of the immune system
46. Isolation of cDNA encoding immunoglobulin light chain from common carp (Cyprinus carpio L.)
47. N-terminal amino-acid sequence of African lungfish immunoglobulin light chains
48. Structure and diversity of Mexican axelotl lambda light chains
49. Amino acid sequence of constant region of immunoglobulin light chains from Rana catesbeiana
50. The presence of two antigenetically distinct light chains (κ and λ?) in alligator immunoglobulin
51. cDNA sequence and organisation of the immunoglobulin light chain gene of the duck, Anas platyrhynchos
52. Evolutionary comparison of the avian IgL locus: combinatorial diversity plays a role in the generation of the antibody repertoire in some avian species
53. Complete sequence of a chicken λ light chain immunoglobulin derived from the nucleotide sequence of its mRNA
54. Evolution of the rabbit immunoglobulin κ chain genes
55. Expression of immunoglobulin kappa and lambda chains in mink
56. Isolation and sequence of sheep Ig'H and L chain cDNA
57. Light chain isotype regulation in the horse. Characterization of Ig κ genes
58. Structural studies on normal horse immunoglobulin light chains. Detection of κ-type N-terminal sequences
59. Nucleotide sequences and expression of cDNAs for a bovine anti-testosterone monoclonal antibody
60. The structure of the cDNA and the chromosomal localisation of the gene of the immunoglobulin lambda-light chains in the American mink
61. Sequence analysis of porcine immunoglobulin light chain cDNAs
62. The immunoglobulin lambda locus in rat consists of two Cl genes and a single Vλ gene
63. The complete amino acid sequence of a mouse κ light chain
64. Characterization and DNA sequence of the b6w2 allotype of rabbit immunoglobulin kappa 1 light chain (β locus)
65. Hamster cDNA homologs to the mouse immunoglobulin kappa constant and Igk-V45.1 genes