Insights into the sites of X ray and neutron induced chromosomal aberrations in human lymphocytes using cobra-mfish

Radiation Protection Dosimetry

Volumn 99, Issue 1-4, 2002, Pages 189-192

  Darroudi, F ^a   Bezrookove, V ^a   Fomina, J ^a   Mesker, W E ^a   Wiegant, J C A G ^a   Raap, A K ^a   Tanke, H J ^a   Cherubini, R ^b   Goodhead, D T ^b   Menzel, H G ^b   Ottolenghi, A ^b  

^a LEIDEN UNIVERSITY MEDICAL CENTER   (Netherlands)

^b NONE

Author keywords

[No Author keywords available]

Indexed keywords

ADULT; ARTICLE; ASSAY; CHEMICAL LABELING; CHROMOSOME ABERRATION; CHROMOSOME BREAKAGE; CHROMOSOME INSERTION; CHROMOSOME PAINTING; CHROMOSOME TRANSLOCATION; COLOR; CONTROLLED STUDY; DOSE RESPONSE; FEMALE; FLUORESCENCE IN SITU HYBRIDIZATION; HUMAN; HUMAN CELL; HUMAN CHROMOSOME; LINEAR ENERGY TRANSFER; LYMPHOCYTE; MALE; NEUTRON RADIATION; RADIATION EXPOSURE; X RAY; CELL CULTURE; KARYOTYPING; MIDDLE AGED; NEUTRON; PHYSIOLOGY; RADIATION RESPONSE;

DNA;

CELLS, CULTURED; CHROMOSOME ABERRATIONS; DNA; DOSE-RESPONSE RELATIONSHIP, RADIATION; FEMALE; HUMANS; IN SITU HYBRIDIZATION, FLUORESCENCE; KARYOTYPING; LYMPHOCYTES; MIDDLE AGED; NEUTRONS; X-RAYS;

EID: 0036023768     PISSN: 01448420     EISSN: None     Source Type: Journal    
DOI: 10.1093/oxfordjournals.rpd.a006758     Document Type: Article

References (22)

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2. Frequencies of X-ray Induced Chromosome Translocations in Human Peripheral Lymphocytes as Detected by in situ Hybridisation using Chromosome-specific DNA Libraries
3. Rejoining and Misrejoining of Radiation Induced Chromatin Breaks Experiments with Human Lymphocytes
4. Kinetics of the Formation of Chromosome Aberrations in X-irradiated Human Lymphocytes, using PCC and FISH
5. Use of FISH Translocations Analysis for Retrospective Biological Dosimetry: How Stable are Stable Chromosome Translocations?
6. Parameters of the Human Genome
7. FISH 'Painting' Patterns Resulting from Complex Exchanges
8. Detecting 'Hidden' Exchange Events within X-ray-induced Aberrations using Multi-colour Chromosome Paints
9. Dose-Response Curve for Simple and Complex Chromosome Aberrations Induced by X-rays and Detected using Fluorescence in situ Hybridization
10. 238Pu Alpha-particles and Detected by Fluorescence in situ Hybridization using Single Chromosome-specific Probes
11. Multicolour FISH Painting for the Analysis of Chromosomal Aberrations Induced by 220 kV X-rays and Fission Neutrons
12. Complex Chromosome Aberrations in Peripheral Blood Lymphocytes as a Potential Biomarker of Exposure to High-LET Alpha-particles
13. Multicolour Spectral Karyotyping of Human Chromosomes
14. Karyotyping Human Chromosomes by Combinatorial Multi-fluor FISH
15. New Strategy for Multi-colour Fluorescence in situ Hybridisation: COBRA: Combined Binary Ratio Labelling
16. New Giemsa Method for Differential Staining of Sister Chromatids
17. The Variability of Translocations Yields amongst Control Populations
18. Nomenclature Systems for FISH-painted Chromosome Aberrations
19. Kinetics of Chromosome Aberration Formations with Neutrons, using PCC and FISH
20. Frequencies and Types of Exchange Aberrations by X-rays and Neutrons in Chinese Hamster Splenocytes Detected by FISH using Chromosome-specific DNA Libraries
21. Discrimination between Complete and Incomplete Chromosome some Exchanges in X-irradiated Human Lymphocytes using FISH with Pan-centromeric and Chromosome-specific DNA Probes in Combination with Telomeric Probe
22. Accurate Detection of True Incomplete Exchanges in Human Lymphocytes Exposed to Neutron Radiation using Chromosome Painting in Combination with a Telomeric PNA Probe