Estrogen receptor inducibility of the human Na+/H+ exchanger regulatory factor/ezrin-radixin-moesin binding protein 50 (NHE-RF/EBP50) gene involving multiple half-estrogen response elements

Molecular Endocrinology

Volumn 16, Issue 8, 2002, Pages 1828-1839

  Ediger, Tracy R ^a   Park, Seong Eun ^b   Katzenellenbogen, Benita S ^a,b  

^a UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

^b UNIVERSITY OF ILLINOIS AT URBANA CHAMPAIGN   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

BINDING PROTEIN; DNA; ERM BINDING PROTEIN 50; ESTROGEN RECEPTOR; EZRIN; MESSENGER RNA; MOESIN; RADIXIN; REGULATOR PROTEIN; SODIUM PROTON EXCHANGE PROTEIN; UNCLASSIFIED DRUG; CARRIER PROTEIN; COMPLEMENTARY DNA; PHOSPHOPROTEIN; SODIUM HYDROGEN EXCHANGER REGULATORY FACTOR; SODIUM-HYDROGEN EXCHANGER REGULATORY FACTOR; TRANSCRIPTION FACTOR SP1;

AMINO ACID SEQUENCE; ARTICLE; CONTROLLED STUDY; CYTOSKELETON; DNA LIBRARY; ELECTROPHORETIC MOBILITY; ESTROGEN RESPONSIVE ELEMENT; EXON; GENE DELETION; GENETIC TRANSFECTION; HORMONE RECEPTOR INTERACTION; HUMAN; HUMAN CELL; MOLECULAR RECOGNITION; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; PROMOTER REGION; PROTON SODIUM EXCHANGE; REPORTER GENE; TATA BOX; TRANSACTIVATION; TRANSCRIPTION REGULATION; BINDING SITE; CELL LINE; GENETICS; IN VITRO STUDY; METABOLISM; MOLECULAR GENETICS; REGULATOR GENE;

AMINO ACID SEQUENCE; BASE SEQUENCE; BINDING SITES; CARRIER PROTEINS; CELL LINE; DNA, COMPLEMENTARY; EXONS; GENES, REGULATOR; HUMAN; IN VITRO; MOLECULAR SEQUENCE DATA; PHOSPHOPROTEINS; PROMOTER REGIONS (GENETICS); RECEPTORS, ESTROGEN; SODIUM-HYDROGEN ANTIPORTER; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; TRANSCRIPTION FACTOR, SP1; HUMANS; SP1 TRANSCRIPTION FACTOR;

EID: 0036020502     PISSN: 08888809     EISSN: None     Source Type: Journal    
DOI: 10.1210/me.2001-0290     Document Type: Article

References (57)

1. The multifaceted mechanisms of estradiol and estrogen receptor signaling
2. Coregulator codes of transcriptional regulation by nuclear receptors
3. The nuclear receptor superfamily: The second decade
4. Mechanisms of action and cross-talk between estrogen receptor and progesterone receptor pathways
5. Estrogen receptors: Selective ligands, partners, and distinctive pharmacology
6. Estrogen receptor transcription and transactivation: Estrogen receptor a and estrogen receptor β: Regulation by selective estrogen receptor modulators and importance in breast cancer
7. Identification of an estrogen response element upstream of the human c-fos gene that binds the estrogen receptor and the AP-1 transcription factor
8. Estrogen regulation of the insulin-like growth factor I gene transcription involves an AP-1 enhancer
9. Functional synergy between the transcription factor Sp1 and the estrogen receptor
10. Estrogen-induced c-fos protooncogene expression in MCF-7 human breast cancer cells: Role of estrogen receptor Sp1 complex formation
11. Estrogen receptor regulation of the Na+/H+ exchanger regulatory factor
12. + exchanger requires a dissociable phosphoprotein cofactor
13. Expanding the role of NHERF, a PDZ-domain containing protein adapter, to growth regulation
14. The roles of PDZ-containing proteins in PLC-β-mediated signaling
15. An apical PDZ protein anchors the cystic fibrosis transmembrane conductance regulator to the cytoskeleton
16. + exchanger regulatory factor family of PDZ proteins
17. Interaction of the type IIa Na/Pi cotransporter with PDZ proteins
18. Identification of EBP50: A PDZ-containing phosphoprotein that associates with members of the ezrin-radixin-moesin family
19. Effect of estradiol on the ultrastructure of the MCF-7 human breast cancer cells in culture
20. + exchange
21. Yes-associated protein 65 localizes p62(c-Yes) to the apical compartment of airway epithelia by association with EBP50
22. Platelet-derived growth factor receptor association with Na(+)/H(+) exchanger regulatory factor potentiates receptor activity
23. Association of mammalian Trp4 and phospholipase C isozymes with a PDZ domain-containing protein, NHERF
24. NHE-RF, a merlin-interacting protein, is primarily expressed in luminal epithelia, proliferative endometrium, and estrogen receptor-positive breast carcinomas
25. The downstream core promoter element, DPE, is conserved from Drosophila to humans and is recognized by TAFII60 of Drosophila
26. The downstream promoter element DPE appears to be as widely used as the TATA box in Drosophila core promoters
27. Cloning of the rat progesterone receptor gene 5′ region and identification of two functionally distinct promoters
28. Three amino acids of the oestrogen receptor are essential to its ability to distinguish an oestrogen- from a glucocorticoid-responsive element
29. Analysis of mechanisms that determine dominant negative estrogen receptor effectiveness
30. Transcriptional regulation of the human quinone reductase gene by antiestrogen-liganded estrogen receptor-α and estrogen receptor-β
31. Identification of multiple, widely spaced estrogen-responsive regions in the rat progesterone receptor gene
32. Estrogen receptor-Sp1 complexes mediate estrogen-induced cathepsin D gene expression in MCF-7 human breast cancer cells
33. Role of estrogen receptor/Sp1 complexes in estrogen-induced heat shock protein 27 gene expression
34. Estrogen-induced retinoic acid receptor α 1 gene expression: Role of estrogen receptor-Sp1 complex
35. Estrogen induces adenosine deaminase gene expression in MCF-7 human breast cancer cells: Role of estrogen receptor-Sp1 interactions
36. Transcriptional activation of thymidylate synthase by 17β-estradiol in MCF-7 human breast cancer cells
37. Regulation of prothymosin α gene expression by estrogen in estrogen receptor-containing breast cancer cells via upstream half-palindromic estrogen response element motifs
38. Estrogen receptor interaction with estrogen response elements
39. Function of directly repeated half-sites as response elements for steroid hormone receptors
40. Estrogen receptor α interaction with estrogen response element half-sites from the rat prolactin gene
41. A far upstream estrogen response element of the ovalumin gene contains several half-palindromic 5′-TGACC-3′ motifs acting synergistically
42. Changes of cell morphology and prolactin secretion induced by 2-Br-α-ergocryptine, estradiol, and thyrotropin-releasing hormone in rat anterior pituitary cells in culture
43. Changes in the apical microfilaments of rat uterine epithelial cells in response to estradiol and progesterone
44. A role for oestrogens in the male reproductive system
45. Identification of EPI64, a TBC/rabGAP domain-containing microvillar protein that binds to the first PDZ domain of EBP50 and E3KARP
46. Stimulation of estrogen receptor-mediated transcription and alteration in the phosphorylation state of the rat uterine estrogen receptor by estrogen, cyclic adenosine monophosphate, and insulin-like growth factor-I
47. Estrogen rapidly induces the phosphorylation of the cAMP response element binding protein in rat brain
48. Involvement of cyclic AMP response element binding protein (CREB) and estrogen receptor phosphorylation in the synergistic activation of the estrogen receptor by estradiol and protein kinase activators
49. Physiological coupling of growth factor and steroid receptor signaling pathways: Estrogen receptor knockout mice lack estrogen-like response to epidermal growth factor
50. Detailed deletion analysis of sporadic breast tumors defines an interstitial region of allelic loss on 17q25
51. A region of interstitial 17q25 allelic loss in ovarian tumors coincides with a defined region of loss in breast tumors
52. 17q21-q25 aberrations in breast cancer: Combined allelotyping and CGH analysis reveals 5 regions of allelic imbalance among which two correspond to DNA amplification
53. Frequent allelic loss at the TOC locus on 17q25.1 in primary breast cancers
54. Differential DNA-binding abilities of estrogen receptor occupied with two classes of antiestrogens: Studies using human estrogen receptor overexpressed in mammalian cells
55. Human estrogen receptor mutants with altered estrogen and antiestrogen ligand discrimination
56. Estrogen response elements function as allosteric modulators of estrogen receptor conformation
57. Sp1 binding sites and an estrogen response element half-site are involved in regulation of the human progesterone receptor A promoter