A convenient synthesis by microwave heating and pharmacological evaluation of novel benzoyltriazole and saccharine derivatives as 5-HT1A receptor ligands

European Journal of Pharmaceutical Sciences

Volumn 16, Issue 1-2, 2002, Pages 15-28

  Caliendo, Giuseppe ^a   Fiorino, Ferdinando ^a   Perissutti, Elisa ^a   Severino, Beatrice ^a   Scolaro, Daniela ^a   Gessi, Stefania ^b   Cattabriga, Elena ^b   Borea, Pier Andrea ^b   Santagada, Vincenzo ^a  

^a UNIVERSITY OF NAPLES FEDERICO II   (Italy)

^b UNIVERSITY OF FERRARA   (Italy)

Author keywords

5 HT Receptors; Benzoyltriazole; Medicinal chemistry; Microwave; Saccharine

Indexed keywords

BIOSYNTHESIS; DERIVATIVES; MICROWAVE HEATING;

PHARMACOLOGICAL EVALUATION; RECEPTORS;

DRUG PRODUCTS;

ALPHA 1 ADRENERGIC RECEPTOR; ALPHA 2 ADRENERGIC RECEPTOR; DOPAMINE 1 RECEPTOR; DOPAMINE 2 RECEPTOR; SACCHARIN DERIVATIVE; SEROTONIN 1A RECEPTOR; SEROTONIN 2A RECEPTOR; SEROTONIN 2C RECEPTOR; TRIAZOLE DERIVATIVE; DRUG DERIVATIVE; LIGAND; PIPERAZINE DERIVATIVE; SACCHARIN; SEROTONIN 1 RECEPTOR; SEROTONIN RECEPTOR;

ARTICLE; DRUG DESIGN; DRUG PROTEIN BINDING; DRUG SYNTHESIS; HEATING; METHODOLOGY; MICROWAVE RADIATION; PRIORITY JOURNAL; ANIMAL; BRAIN; CHEMISTRY; IN VITRO STUDY; METABOLISM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; RADIOASSAY; RAT; STRUCTURE ACTIVITY RELATION; SYNTHESIS; WISTAR RAT;

ANIMAL; BRAIN; HEATING; IN VITRO; LIGANDS; MAGNETIC RESONANCE SPECTROSCOPY; MICROWAVES; PIPERAZINES; RADIOLIGAND ASSAY; RATS; RATS, WISTAR; RECEPTORS, SEROTONIN; SACCHARIN; STRUCTURE-ACTIVITY RELATIONSHIP; SUPPORT, NON-U.S. GOV'T; TRIAZOLES; ANIMALS; RECEPTOR, SEROTONIN, 5-HT2A; RECEPTOR, SEROTONIN, 5-HT2C; RECEPTORS, SEROTONIN, 5-HT1;

EID: 0036020059     PISSN: 09280987     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0928-0987(02)00045-3     Document Type: Article

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