4-(4-Fluorobenzoyl)-1-[2-(4-iodo-2,5-dimethoxyphenyl)ethyl]piperidine and its derivatives: Synthesis and affinity at 5-HT(2A), 5-HT(2B) and 5- HT(2C) serotonin receptors

European Journal of Medicinal Chemistry

Volumn 34, Issue 10, 1999, Pages 843-852

  Claudi, Francesco ^a   Scoccia, Loredana ^a   Giorgioni, Gianfabio ^a   Accorroni, Beatrice ^a   Marucci, Gabriella ^a   Gessi, Stefania ^b   Siniscalchi, Anna ^b   Borea, Pier Andrea ^b  

^a UNIVERSITY OF CAMERINO   (Italy)

^b UNIVERSITY OF FERRARA   (Italy)

Author keywords

4 (4 Fluorobenzoyl) 1 2 (4 iodo 2,5 dimethoxyphenyl)ethyl piperidine derivatives; 5 HT(2A) antagonistic activity; 5 HT(2A), 5 HT(2B), and 5 HT(2C) serotonin receptor affinity; Synthesis

Indexed keywords

4 (4 FLUOROBENZOYL) 1 [2 (4 IODO 2,5 DIMETHOXYPHENYL)ETHYL]PIPERIDINE; KETANSERIN; SEROTONIN 2A ANTAGONIST; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; BINDING SITE; DRUG CONFORMATION; DRUG RECEPTOR BINDING; DRUG SYNTHESIS; MOLECULAR INTERACTION; NONHUMAN; RAT; RECEPTOR BLOCKING; STRUCTURE ACTIVITY RELATION;

EID: 0032694036     PISSN: 02235234     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0223-5234(99)00208-1     Document Type: Article

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