Differential modulation of efficiency in a food-rewarded "differential reinforcement of low-rate" 72-s schedule in rats by norepinephrine and serotonin reuptake inhibitors

Psychopharmacology

Volumn 162, Issue 2, 2002, Pages 156-167

  Dekeyne, Anne ^a   Gobert, Alain ^a   Auclair, Agnès ^a   Girardon, Sylvie ^a   Millan, Mark J ^a  

^a INSTITUT DE RECHERCHES SERVIER   (France)

Author keywords

Antidepressant; Dopamine reuptake inhibitor; DRL 72 s; Norepinephrine reuptake inhibitor; Serotonin reuptake inhibitor; Tricyclics

Indexed keywords

ADRENERGIC RECEPTOR AFFECTING AGENT; DOPAMINE; DOPAMINE UPTAKE INHIBITOR; NORADRENALIN; SEROTONIN; SEROTONIN UPTAKE INHIBITOR; TRICYCLIC ANTIDEPRESSANT AGENT; 1 (DIMETHYLAMINOMETHYL 5 METHOXYBENZOCYCLOBUTAN 1 YL)CYCLOHEXANOL; 1 [2 (BENZHYDRYLOXY)ETHYL] 4 (3 PHENYLPROPYL)PIPERAZINE; AMFEBUTAMONE; BRAIN MONOAMINE; CITALOPRAM; CYCLOHEXANOL DERIVATIVE; DESIPRAMINE; FLUVOXAMINE; IMIPRAMINE; MIANSERIN; NORADRENALIN UPTAKE INHIBITOR; NORTRIPTYLINE; PAROXETINE; REBOXETINE; S 33005; UNCLASSIFIED DRUG; VENLAFAXINE;

ANIMAL; ARTICLE; BRAIN; COMPARATIVE STUDY; DIFFERENTIAL THRESHOLD; DOSE RESPONSE; DRUG EFFECT; EATING; INSTRUMENTAL CONDITIONING; LOCOMOTION; MALE; METABOLISM; RAT; REINFORCEMENT; WISTAR RAT; ANIMAL BEHAVIOR; ANIMAL EXPERIMENT; CONTROLLED STUDY; DRUG EFFICACY; FOOD INTAKE; FRONTAL CORTEX; MODULATION; NONHUMAN; PRIORITY JOURNAL; REWARD;

ADRENERGIC UPTAKE INHIBITORS; ANIMALS; ANTIDEPRESSIVE AGENTS, TRICYCLIC; BRAIN; CONDITIONING, OPERANT; DIFFERENTIAL THRESHOLD; DOPAMINE; DOPAMINE UPTAKE INHIBITORS; DOSE-RESPONSE RELATIONSHIP, DRUG; EATING; LOCOMOTION; MALE; NOREPINEPHRINE; RATS; RATS, WISTAR; REINFORCEMENT SCHEDULE; SEROTONIN; SEROTONIN UPTAKE INHIBITORS; ANIMAL; COMPARATIVE STUDY;

EID: 0036019546     PISSN: 00333158     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00213-002-1070-x     Document Type: Article

References (71)

1. Effect of central 5-hydroxytryptamine depletion on tolerance of delay of reinforcement: Evidence from performance in a discrete-trials "time-left" procedure
2. Effects of imipramine-like drugs and serotonin uptake blockers on delay of reward in rats. Possible implication in the behavioral mechanism of action of antidepressants
3. Serotonin and tolerance to delay of reward in rats
4. Chronic L-deprenyl treatment alters brain monoamine levels and reduces impulsiveness in an animal model of attention-deficit/hyperactivity disorder
5. BIMT 17: A putative antidepressant with a fast onset of action?
6. Current and potential drugs for treatment of obesity
7. Effects of paroxetine upon rats responding on a DRL-72 s schedule
8. Effects of corticotropin releasing factor, desipramine and haloperidol on a DRL schedule of reinforcement
9. Current concepts in the management of obesity
10. The serotonin-1 A receptor antagonist WAY-100635 modifies fluoxetine's antidepressant-like profile on the differential reinforcement of low rates 72-s schedule in rats
11. 1A receptor stimulation: Differences in differential reinforcement of low rate 72-second performance and response to serotonergic drugs
12. Reversal of fenfluramine and fluoxetine anorexia by 8-OH-DPAT is attenuated following raphe injection of 5,7-dihydroxytryptamine
13. Comparison of desipramine, amitriptyline, zimelidine, and alaproclate in six animal models used to investigate antidepressant drugs
14. Discriminative stimulus properties of the selective norepinephrine reuptake inhibitor, reboxetine, in rats
15. Active behaviors in the rat forced swimming test differentially produced by serotonergic and noradrenergic antidepressants
16. Noradrenaline-selective versus serotonin-selective antidepressant therapy: Differential effects on social functioning
17. Antidepressant drugs: Does it matter if they inhibit the reuptake of noradrenaline or serotonin?
18. The pharmacology of impulsive behaviour in rats. V: The effects of drugs on responding under a discrimination task using unreliable visual stimuli
19. Effects of combined or separate 5,7-dihydroxytryptamine lesions of the dorsal and median raphe nuclei on responding maintained by a DRL 20 s schedule of food reinforcement
20. Antidepressants
21. The selective norepinephrine reuptake inhibitor, LY368975, reduces food consumption in animal models of feeding
22. Comparison of the effects of mianserin and its enantiomers and metabolites on a behavioral screen for antidepressant activity
23. Rhythm and blues. Neurochemical, neuropharmacological and neurophysiological implications of a hypothesis of circadian rhythm dysfunction in the affective disorders
24. The enhancement of social functioning as a therapeutic principle in the management of depression
25. 5-Hydroxytryptamine and impulsive control: Prospects for a behavioural analysis
26. Effects of imipramine, bupropion, chlorpromazine, and clozapine on differential-reinforcement-of-low-rate (DRL) >72-s and >36-s schedules in rat
27. Can the DRL 72 s schedule selectively reveal antidepressant drug activity?
28. Serotonergic mediation of DRL 72 s behavior: Receptor subtype involvement in a behavioral screen for antidepressant drugs
29. Differential reinforcement of low response rate (DRL-72 s) schedule: Effects of antidepressants
30. Differential reinforcement of low rates: A selective critique
31. Hypothalamic serotonin in control of eating behavior, meal size, and body weight
32. Long-term central 5-HT depletions resulting from repeated administration of MDMA enhances the effects of single administration of MDMA on schedule-controlled behavior of rats
33. Selective inhibition of MAO-A, not MAO-B, results in antidepressant-like effects on DRL 72-s behavior
34. Effects of selective 5-hydroxytryptamine-2 and non-selective 5-hydroxytryptamine antagonists on the differential-reinforcement-of-low-rate 72-second schedule
35. 1 receptors in antidepressant-like drug effects on differential-reinforcement-of-low-rate 72-second behavior
36. 2 antagonists have antidepressant-like effects on differential-reinforcement-of-low-rate 72-second schedule
37. Effects of caffeine and PD 116,600 on the differential-reinforcement-of-low-rate 72-S (DRL 72-S) schedule of reinforcement
38. 2C receptor agonists: Pharmacological characteristics and therapeutic potential
39. Reboxetine: A double-blind comparison with fluoxetine in major depressive disorder
40. The effects of tricyclic antidepressants on performance under a differential-reinforcement-of-low-rates schedule in rats
41. Differential effects of imipramine in rats as a function of DRL schedule value
42. 2C receptors: A comparison with citalopram
43. Reciprocal autoreceptor and heteroreceptor control of serotonergic, dopaminergic and noradrenergic transmission in the frontal cortex: Relevance to the actions of antidepressant agents
44. S33005, a novel ligand at both serotonin and norepinephrine transporters: II. Behavioural profile in comparison to venlafaxine, reboxetine, citalopram and clomipramine
45. S33005, a novel ligand at both serotonin and norepinephrine transporters: I. Receptor binding, electrophysiological and neurochemical profile in comparison to venlafaxine, reboxetine, citalopram and clomipramine
46. Behavioral effects of beta adrenergic agonists and antidepressant drugs after down-regulation of beta-2 adrenergic receptors by clenbuterol
47. Effects of the beta-2 adrenergic agonist zinterol on DRL behavior and locomotor activity
48. Effects of monoamine oxidase inhibitors on performance during differential reinforcement of low response rate
49. Differential-reinforcement-of-low-rate 72-second schedule: Selective effects of antidepressant drugs
50. Involvement of beta-1 and beta-2 adrenergic receptors in the antidepressant-like effects of centrally administered isoproterenol
51. Preclinical evidence on the psychotropic profile of fluvoxamine
52. Neurotransmitter receptor and transporter binding profile of antidepressants and their metabolites
53. Similar effects of antidepressant and non-antidepressant drugs on behavior under an interresponse-time >72-s schedule
54. Preclinical pharmacology of citalopram
55. 2 receptor antagonists and GBR 12909 and GBR 12935 dopamine uptake inhibitors in the nucleus accumbens
56. Dose-dependent noradrenergic and serotonergic properties of venlafaxine in animal models indicative of antidepressant activity
57. Fluoxetine prevents the disruptive effects of fenfluramine on differential-reinforcement-of-low-rate 72-second schedule performance
58. Buspirone, gepirone, ipsapirone, and zalospirone have distinct effects on the differential-reinforcement-of-low-rate 72-s schedule when compared with 5-HTP and diazepam
59. Comparison of either norepinephrine-uptake inhibitors or phentermine combined with serotonergic agents on food intake in rats
60. Amphetamine analogs have differential effects on the DRL 36-s schedule performance
61. 2-adrenoceptor antagonists idazoxan and yohimbine increase rates of DRL responding in rats
62. Clinical efficacy of reboxetine in major depression
63. Venlafaxine, a novel antidepressant compound
64. Behavioral screen for antidepressants: The effects of drugs and electroconvulsive shock on performance under a differential-reinforcement-of-low-rate schedule
65. The role of noradrenergic and serotonergic systems in the screening of antidepressant drugs
66. The behavioral effects of sertraline, fluoxetine, and paroxetine differ on the differential-reinforcement-of-low-rate 72-second operant schedule in the rat
67. Pharmacological profile of antidepressants and related compounds at human monoamine transporters
68. Flesinoxan shows antidepressant activity in a DRL 72-s screen
69. Reboxetine: A pharmacologically potent, selective, and specific norepinephrine reuptake inhibitor
70. Does the effect of central 5-hydoxytryptamine depletion on timing depend on motivational change?
71. Pure timing in temporal differentiation