Selective killing of cancer cells based on translational control of a suicide gene

Cancer Gene Therapy

Volumn 9, Issue 7, 2002, Pages 573-578

  DeFatta, Robert J ^a   Li, Yuan ^a   De Benedetti, Arrigo ^a  

^a LOUISIANA STATE UNIVERSITY HEALTH SCIENCES CENTER   (United States)

Author keywords

Gene expression in cancer; Herpes thymidine kinase; Translation initiation factor eIF4E; Translational control

Indexed keywords

GANCICLOVIR; INITIATION FACTOR 4E; THYMIDINE KINASE; ANTIVIRUS AGENT; MESSENGER RNA;

5' UNTRANSLATED REGION; ARTICLE; BREAST CANCER; CANCER CELL; CELL KILLING; CONCENTRATION RESPONSE; CONTROLLED STUDY; GENE CONTROL; GENE OVEREXPRESSION; HERPES SIMPLEX VIRUS; HUMAN; HUMAN CELL; PRIORITY JOURNAL; RNA TRANSLATION; SUICIDE GENE; TRANSLATION REGULATION; BREAST TUMOR; CELL CULTURE; CELL SURVIVAL; DOSE RESPONSE; GENE THERAPY; GENE VECTOR; GENETIC TRANSFECTION; GENETICS; METABOLISM; METHODOLOGY; PHENOTYPE; PLASMID; PROTEIN SYNTHESIS; WESTERN BLOTTING;

ANTIVIRAL AGENTS; BLOTTING, WESTERN; BREAST NEOPLASMS; CELL SURVIVAL; DOSE-RESPONSE RELATIONSHIP, DRUG; EUKARYOTIC INITIATION FACTOR-4E; GANCICLOVIR; GENE THERAPY; GENETIC VECTORS; HUMAN; PHENOTYPE; PLASMIDS; RNA, MESSENGER; SUPPORT, U.S. GOV'T, P.H.S.; THYMIDINE KINASE; TRANSFECTION; TRANSLATION, GENETIC; TUMOR CELLS, CULTURED; HUMANS; PROTEIN BIOSYNTHESIS;

EID: 0036019373     PISSN: 09291903     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.cgt.7700468     Document Type: Article

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