Diphencyprone immunotherapy alters anti-hair follicle antibody status in patients with alopecia areata

European Journal of Dermatology

Volumn 12, Issue 4, 2002, Pages 327-334

  Tobin, Desmond J ^a   Gardner, Sarah H ^a   Lindsey, Nigel J ^a   Hoffmann, Rolf ^a   Happle, Rudolf ^a   Freyschmidt Paul, Pia ^a  

^a UNIVERSITY OF BRADFORD   (United Kingdom)

Author keywords

Allergic contact dermatitis; Alopecia areata; Autoantibody; Autoantigen; Diphencyprone; T cell

Indexed keywords

AUTOANTIBODY; AUTOANTIGEN; DIPHENCYPRONE; HAIR FOLLICLE ANTIBODY; IMMUNOGLOBULIN G; IMMUNOGLOBULIN G ANTIBODY; UNCLASSIFIED DRUG; CYCLOPROPANE DERIVATIVE;

ADOLESCENT; ADULT; ALOPECIA AREATA; ANTIBODY TITER; ANTIGEN ANTIBODY REACTION; ARTICLE; AUTOIMMUNE DISEASE; CHILD; CLINICAL ARTICLE; CLINICAL FEATURE; CONTACT SENSITIZATION; DISEASE SEVERITY; DOWN REGULATION; FEMALE; HAIR FOLLICLE; HAIR GROWTH; HAIR LOSS; HUMAN; IMMUNOBLOTTING; IMMUNOFLUORESCENCE; IMMUNOGLOBULIN BLOOD LEVEL; IMMUNOTHERAPY; MALE; SCALP; SKIN ALLERGY; T LYMPHOCYTE; BLOOD; DRUG EFFECT; FLUORESCENT ANTIBODY TECHNIQUE; IMMUNOLOGY; MIDDLE AGED; TOPICAL DRUG ADMINISTRATION; TREATMENT OUTCOME;

ADMINISTRATION, TOPICAL; ADOLESCENT; ADULT; ALOPECIA AREATA; AUTOANTIGENS; CHILD; CYCLOPROPANES; FEMALE; FLUORESCENT ANTIBODY TECHNIQUE, INDIRECT; HAIR FOLLICLE; HUMAN; IMMUNOTHERAPY; MALE; MIDDLE AGE; TREATMENT OUTCOME; HUMANS; MIDDLE AGED;

EID: 0036018514     PISSN: 11671122     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

References (32)

1. Incidence of alopecia areata in Olmsted County, Minnesota, 1975-1989
2. Comparison of alopecia areata in human and non-human mammalian species
3. Immunology of alopecia areata
4. Morphologic changes in pilosebaceous units and anagen hairs in alopecia areata
5. Characteristics of autoimmune disease
6. Autoimmune hair loss (alopecia areata) transferred by T lymphocytes to human scalp explants on SCID mice
7. Equine alopecia areata autoantibodies target multiple hair follicle antigens and may alter hair growth in passive transfer studies
8. Ultrastructural observations on the hair bulb melanocytes and melanosomes in acute alopecia areata
9. Melanocyte-associated T cell epitopes can function as autoantigens for transfer of alopecia areata to human scalp explants on Prkdc(scid) mice
10. Different populations of melanocytes are present in hair follicles and epidermis
11. Experimental induction of alopecia areata-like hair loss in C3H/HeJ mice using full-thickness skin grafts
12. Antibodies to hair follicles in alopecia areata
13. Hair follicle structures targeted by antibodies in patients with alopecia areata
14. Autoantibodies to hair follicles in C3H/HeJ mice with alopecia areata-like hair loss
15. Failure of passive transfer of serum from patients with alopecia areata and alopecia universalis to inhibit hair growth in transplants of human scalp skin grafted on to nude mice
16. Hair regrowth. Therapeutic agents
17. Topical immunotherapy in alopecia areata: What, How and Why?
18. Contact allergy as a therapeutic tool for alopecia areata: Application of squaric acid dibutylester
19. Topical therapy of alopecia areata with squaric acid dibutylester
20. Treatment of alopecia areata with squaric acid dibutylester
21. Treatment of alopecia areata with squaric acid dibutylester
22. Current and potential agents for the treatment of alopecia areata
23. Topical immunotherapy changes the composition of the peribulbar infiltrate in alopecia areata
24. Abnormal expression of class I and class II major histocompatibility antigens in alopecia areata: Modulation by topical immunotherapy
25. Successful treatment of alopecia areata-like hair loss with the contact sensitizer squaric acid dibutylester (SADBE) in C3H/HeJ mice
26. Alopecia areata but not androgenetic alopecia is characterized by a restricted and oligoclonal T cell receptor-repertoire among infiltrating lymphocytes
27. T-cell receptor Vb chain variable gene use in alopecia areata totalis
28. Alopecia areata is associated with antibodies to hair follicle-specific antigens located predominantly in the proliferative region of hair follicles
29. The pathogenesis of alopecia areata
30. Is alopecia areata an autoimmune-response against melanogenesis-related proteins, exposed by abnormal MHC class I expression in the anagen hair bulb?
31. gld mice are relatively resistant to the induction of alopecia areata by grafting of alopeic areata-affected skin from C3H/HeJ mice
32. B lymphocytes are crucial antigen-presenting cells in the pathogenic autoimmune response to GAD65 antigen in non obese diabetic mice