Teaching target-oriented and diversity-oriented organic synthesis at Harvard University

Chemistry and Biology

Volumn 9, Issue 5, 2002, Pages 535-541

  Burke, Martin D ^a   Lalic, Gojko ^a  

^a HARVARD UNIVERSITY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ORGANIC COMPOUND;

ALKYLATION; ARTICLE; CHEMISTRY; CURRICULUM; DRUG DESIGN; EDUCATION; HISTORY; HUMAN; METHODOLOGY; ORGANIC CHEMISTRY; SYNTHESIS; TEACHING; UNIVERSITY;

ALKYLATION; CHEMISTRY, ORGANIC; CURRICULUM; DRUG DESIGN; HISTORY, 20TH CENTURY; HISTORY, 21ST CENTURY; HUMANS; ORGANIC CHEMICALS; TEACHING; UNIVERSITIES;

EID: 0036015844     PISSN: 10745521     EISSN: None     Source Type: Journal    
DOI: 10.1016/S1074-5521(02)00143-6     Document Type: Review

References (15)

1. The logic of chemical synthesis: Multistep synthesis of complex carbogenic molecules (Nobel lecture)
2. Recent advances in the total synthesis of steroids via intramolecular cycloaddition reactions
3. The intramolecular Diels-Alder reaction in organic synthesis
4. Target-oriented and diversity-oriented organic synthesis in drug discovery
5. Use of biomimetic diversity-oriented synthesis to discover galanthamine-like molecules with biological properties beyond those of the natural product
6. Total synthesis of the L-hexoses
7. A strategy for macrocyclic ring closure and functionalization aimed toward split-pool synthesis
8. Schiff base catalysts for the asymmetric strecker reaction identified and optimized from parallel synthetic libraries
9. Tandem [4+2]/[3+2] cycloadditions of nitroalkanes. 11. The synthesis of (+)-crotanecine
10. Pairwise use of complexity-generating reactions in diversity-oriented organic synthesis