Involvement of amino-acid side chains of membrane proteins in the binding of glutathione to pig cerebral cortical membranes

Neurochemical Research

Volumn 27, Issue 5, 2002, Pages 389-394

  Hermann, A ^a,c   Varga, V ^a,c   Oja, S S ^a,b   Saransaari, P ^a   Janaky R ^a  

^a UNIVERSITY OF TAMPERE MEDICAL SCHOOL   (Finland)

^b TAMPERE UNIVERSITY HOSPITAL   (Finland)

^c UNIVERSITY OF DEBRECEN   (Hungary)

Author keywords

Cerebral cortex; Chemical modification; Cysteinyl, arginyl and lysyl residues; Disulfide bonds; Glutathione binding; Pig; Synaptic membranes

Indexed keywords

ANTIOXIDANT; ARGININE; CYSTEINE; DITHIOTHREITOL; GLUTATHIONE; LYSINE; MEMBRANE PROTEIN; N ETHYLMALEIMIDE; 4,4' DITHIODIPYRIDINE; 4,4'-DIPYRIDYL DISULFIDE; 5,5' DITHIOBIS(2 NITROBENZOIC ACID); AMINO ACID; DISULFIDE; PYRIDINE DERIVATIVE;

AMINO ACID METABOLISM; ANIMAL TISSUE; ARTICLE; BRAIN CORTEX; BRAIN MEMBRANE; CELL FUNCTION; CHEMICAL MODIFICATION; CONCENTRATION RESPONSE; DISULFIDE BOND; DRUG RECEPTOR BINDING; NEUROTRANSMITTER RELEASE; NONHUMAN; PRIORITY JOURNAL; PROTEIN BINDING; SWINE; SYNAPTIC MEMBRANE; SYNAPTIC TRANSMISSION; ANIMAL; CHEMISTRY; DRUG EFFECT; KINETICS; METABOLISM; PHYSIOLOGY;

AMINO ACIDS; ANIMAL; CEREBRAL CORTEX; DISULFIDES; DITHIONITROBENZOIC ACID; GLUTATHIONE; KINETICS; MEMBRANE PROTEINS; PYRIDINES; SUPPORT, NON-U.S. GOV'T; SWINE; SYNAPTIC MEMBRANES; ANIMALS;

ANIMALIA; SUS SCROFA;

EID: 0036014979     PISSN: 03643190     EISSN: None     Source Type: Journal    
DOI: 10.1023/A:1015599830320     Document Type: Article

References (29)

1. Metabolism and functions of glutathione in brain
2. Glutathione and signal transduction in the mammalian CNS
3. Glutathione and glutathione derivatives: Possible modulators of ionotropic glutamate receptors
4. 3H]glutamate in synaptic membranes from rat brain
5. Possible modulation by glutathione of glutamatergic neurotransmission
6. Modulation of glutamate receptor functions by glutathione
7. Glutathione is an endogenous ligand of rat brain N-methyl-D-aspartate (NMDA) and 2-amino-3-hydroxy-5-methyl-4-isoxazolepropionate (AMPA) receptors
8. Specific glutathione binding sites in pig cerebral cortical synaptic membranes
9. 3H]glutathione (GSH) binding sites in synaptic membranes from rat brain
10. 3H]glutathione in brain synaptic membranes
11. Characterization and localization of glutathione binding sites on cultured astrocytes
12. Glutathione: New candidate neuropeptide in the central nervous system
13. Excitatory actions of GSH on neocortex
14. Glutathione-induced sodium currents in neocortex
15. Isolation and structural studies on synaptic complexes from rat brain
16. Ligand binding to porcine ionotropic glutamate receptors with chemically modified arginyl residues
17. Protein measurement with the Folin phenol reagent
18. Determination of sulfhydryl groups with 2'2- or 4'4-dithiodipyridine
19. Protein chemical modification as probe for structure-function relationships
20. Method for determination of the amino acid sequence in peptides
21. Effect of phenylisothiocyanate on organic cation transport in opossum kidney cells
22. Interaction of phenylisothiocyanates with the mitochondrial phosphate carrier. 1. Covalent modification and inhibition of phosphate transport
23. The reaction of phenylglyoxal with arginine residues in proteins
24. Molecular determinants of agonist discrimination by NMDA receptor subunits: Analysis of the glutamate binding site on the NR2B subunit
25. 1-subunit
26. The glycine binding site of the N-methyl-D-aspartate receptor subunit NR1: Identification of novel determinants of coagonist potentiation in the extracellular M3-M4 loop region
27. Mutations in a putative agonist binding region of the AMPA-selective glutamate receptor channel
28. Identification of amino acids in the N-methyl-D-aspartate receptor NR1 subunit that contribute to the glycine binding site