메뉴 건너뛰기




Volumn 19, Issue 3 A, 1999, Pages 1721-1728

Increased neopterin concentrations in patients with cancer: Indicator of oxidative stress?

Author keywords

Cancer; Neopterin; Oxidative stress

Indexed keywords

GAMMA INTERFERON; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; NEOPTERIN; REACTIVE OXYGEN METABOLITE;

EID: 0032782906     PISSN: 02507005     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (158)

References (68)
  • 4
    • 0025236440 scopus 로고
    • Tetrahydrobiopterin biosynthetic activities in human macrophages, fibroblasts, THP-1 and T 24 cells. GPT-cyclohydrolase I is stimulated by interferon-γ, 6-pyruvoyl tetrahydropterin synthase and sepiapterin reductase are constitutively present
    • Werner ER, Werner-Felmayer G, Fuchs D, Hausen A, Reibnegger G, Yim JJ, Pfleiderer W, Wachter H: Tetrahydrobiopterin biosynthetic activities in human macrophages, fibroblasts, THP-1 and T 24 cells. GPT-cyclohydrolase I is stimulated by interferon-γ, 6-pyruvoyl tetrahydropterin synthase and sepiapterin reductase are constitutively present. J Biol Chem 265: 3189-3192, 1990.
    • (1990) J Biol Chem , vol.265 , pp. 3189-3192
    • Werner, E.R.1    Werner-Felmayer, G.2    Fuchs, D.3    Hausen, A.4    Reibnegger, G.5    Yim, J.J.6    Pfleiderer, W.7    Wachter, H.8
  • 6
    • 0024308582 scopus 로고
    • Neopterin as a marker for activation of cellular immunity: Immunologic basis and clinical application
    • Wachter H, Fuchs D, Hausen A, Reibnegger G, Werner ER: Neopterin as a marker for activation of cellular immunity: Immunologic basis and clinical application. Adv Clin Chem 27: 81-141, 1989.
    • (1989) Adv Clin Chem , vol.27 , pp. 81-141
    • Wachter, H.1    Fuchs, D.2    Hausen, A.3    Reibnegger, G.4    Werner, E.R.5
  • 7
    • 0022991358 scopus 로고
    • Peroxide and pteridine: A hypothesis on the regulation of macrophage antimicrobial activity by interferon-γ
    • (Gresser I and Vilcek J, eds). London, Academic Press
    • Nathan CF: Peroxide and pteridine: A hypothesis on the regulation of macrophage antimicrobial activity by interferon-γ. In: Interferon 7 (Gresser I and Vilcek J, eds). London, Academic Press, 1986, pp 125-143.
    • (1986) Interferon , vol.7 , pp. 125-143
    • Nathan, C.F.1
  • 8
    • 0024460738 scopus 로고
    • Tumor necrosis factor-α and lipopolysaccharide enhance interferon-induced tryptophan degradation and pteridine synthesis in human cells
    • Werner-Felmayer G, Werner ER, Fuchs D, Hausen A, Reibnegger G, Wachter H: Tumor necrosis factor-α and lipopolysaccharide enhance interferon-induced tryptophan degradation and pteridine synthesis in human cells. Biol Chem Hoppe- Seyler 370: 1063-1069, 1989.
    • (1989) Biol Chem Hoppe- Seyler , vol.370 , pp. 1063-1069
    • Werner-Felmayer, G.1    Werner, E.R.2    Fuchs, D.3    Hausen, A.4    Reibnegger, G.5    Wachter, H.6
  • 9
    • 0024366741 scopus 로고
    • Altered tryptophan and neopterin metabolism in cancer patients treated with recombinant interleukin-2
    • Brown RR, Lee CM, Kohler PC, Hank JA, Storer BE, Sondel PM: Altered tryptophan and neopterin metabolism in cancer patients treated with recombinant interleukin-2. Cancer Res 49: 4941-4944, 1989.
    • (1989) Cancer Res , vol.49 , pp. 4941-4944
    • Brown, R.R.1    Lee, C.M.2    Kohler, P.C.3    Hank, J.A.4    Storer, B.E.5    Sondel, P.M.6
  • 13
    • 0002527335 scopus 로고
    • Soluble products of immune activation: Neopterin
    • (Rose NR, Conway de Macario E, Fahey JL, Friedman H and Penn GM, eds). Washington DC, American Society for Microbiology
    • Fuchs D, Werner ER, Wachter H: Soluble products of immune activation: neopterin. In: Manual of Clinical Laboratory Immunology (Rose NR, Conway de Macario E, Fahey JL, Friedman H and Penn GM, eds). Washington DC, American Society for Microbiology, 1992, pp 251-255.
    • (1992) Manual of Clinical Laboratory Immunology , pp. 251-255
    • Fuchs, D.1    Werner, E.R.2    Wachter, H.3
  • 14
    • 0018623785 scopus 로고
    • Erhöhte Ausscheidung von Neopterin im Harn von Patienten mit malignen Tumoren und Viruserkrankungen
    • Wachter H, Hausen A, Graßmayr K: Erhöhte Ausscheidung von Neopterin im Harn von Patienten mit malignen Tumoren und Viruserkrankungen. Biol Chem Hoppe-Seyler 360: 1957-1960, 1979.
    • (1979) Biol Chem Hoppe-Seyler , vol.360 , pp. 1957-1960
    • Wachter, H.1    Hausen, A.2    Graßmayr, K.3
  • 15
    • 0023032618 scopus 로고
    • La neopterine urinaire: Interet dans l'exploration de certaines neoplasies
    • Paris
    • Mura P, Piriou A, Tallineau C, Reiss D: La neopterine urinaire: Interet dans l'exploration de certaines neoplasies. Ann Biol Clin (Paris) 44: 505-510, 1986.
    • (1986) Ann Biol Clin , vol.44 , pp. 505-510
    • Mura, P.1    Piriou, A.2    Tallineau, C.3    Reiss, D.4
  • 17
    • 0026328009 scopus 로고
    • Predictive value of interleukin-6 and neopterin in patients with multiple myeloma
    • Reibnegger G, Krainer M, Herold M, Ludwig H, Wachter H, Hulber H: Predictive value of interleukin-6 and neopterin in patients with multiple myeloma. Cancer Res 51: 6250-6253, 1991.
    • (1991) Cancer Res , vol.51 , pp. 6250-6253
    • Reibnegger, G.1    Krainer, M.2    Herold, M.3    Ludwig, H.4    Wachter, H.5    Hulber, H.6
  • 19
    • 0023617545 scopus 로고
    • Clinical significance of neopterin for prognosis and follow-up in ovarian cancer
    • Reibnegger G, Hetzel H, Fuchs D, Fuith LC, Hausen A, Wachter H: Clinical significance of neopterin for prognosis and follow-up in ovarian cancer. Cancer Res 47: 4977-4981, 1987.
    • (1987) Cancer Res , vol.47 , pp. 4977-4981
    • Reibnegger, G.1    Hetzel, H.2    Fuchs, D.3    Fuith, L.C.4    Hausen, A.5    Wachter, H.6
  • 22
  • 23
    • 0023736398 scopus 로고
    • Prognostic significance of urinary neopterin levels in patients with hepatocellular carcinoma
    • Kawasaki H, Watanabe H, Yamada S, Watanabe K, Suyama A: Prognostic significance of urinary neopterin levels in patients with hepatocellular carcinoma. Tohoku J Exp Med 155: 311-318, 1988.
    • (1988) Tohoku J Exp Med , vol.155 , pp. 311-318
    • Kawasaki, H.1    Watanabe, H.2    Yamada, S.3    Watanabe, K.4    Suyama, A.5
  • 24
    • 0031661892 scopus 로고    scopus 로고
    • Neopterin as a prognostic parameter in patients with squamous cell carcinomas of the oral cavity
    • Murr C, Berchtold J, Norer B, Waldhart E, Wachter H, Fuchs D; Neopterin as a prognostic parameter in patients with squamous cell carcinomas of the oral cavity. Int J Cancer 79: 476-480, 1998.
    • (1998) Int J Cancer , vol.79 , pp. 476-480
    • Murr, C.1    Berchtold, J.2    Norer, B.3    Waldhart, E.4    Wachter, H.5    Fuchs, D.6
  • 26
    • 0028153944 scopus 로고
    • Enhancement of hydrogen peroxide-induced luminol-dependent chemiluminescence by neopterin depends on the presence of iron chelator complexes
    • Murr C, Fuchs D, Gössler W, Hausen A, Reibnegger G, Werner ER, Werner- Felmayer G, Esterbauer H, Wachter H: Enhancement of hydrogen peroxide-induced luminol-dependent chemiluminescence by neopterin depends on the presence of iron chelator complexes. FEBS Lett 338: 223-226, 1994.
    • (1994) FEBS Lett , vol.338 , pp. 223-226
    • Murr, C.1    Fuchs, D.2    Gössler, W.3    Hausen, A.4    Reibnegger, G.5    Werner, E.R.6    Felmayer, G.7    Esterbauer, H.8    Wachter, H.9
  • 27
    • 0023951602 scopus 로고
    • Inhibition of monocyte luminol- Dependent chemiluminescence by tetrahydrobiopterin, and the free radical oxidation of tetrahydrobiopterin, dihydrobiopterin and dihydropterin
    • Heales SJR, Blair JA, Meinschad C, Ziegler I: Inhibition of monocyte luminol- dependent chemiluminescence by tetrahydrobiopterin, and the free radical oxidation of tetrahydrobiopterin, dihydrobiopterin and dihydropterin. Cell Biochem Funct 6: 191-195, 1988.
    • (1988) Cell Biochem Funct , vol.6 , pp. 191-195
    • Heales, S.J.R.1    Blair, J.A.2    Meinschad, C.3    Ziegler, I.4
  • 29
    • 0027248803 scopus 로고
    • Inhibitory effect of neopterin on NADPH-dependent superoxide-generating oxidase of rat peritoneal macrophages
    • Kojima S, Nomura T, Icho T, Kajiwara Y, Kitabatake K, Kubota K: Inhibitory effect of neopterin on NADPH-dependent superoxide-generating oxidase of rat peritoneal macrophages. FEBS Lett 329: 125-128, 1993.
    • (1993) FEBS Lett , vol.329 , pp. 125-128
    • Kojima, S.1    Nomura, T.2    Icho, T.3    Kajiwara, Y.4    Kitabatake, K.5    Kubota, K.6
  • 33
    • 0002179257 scopus 로고    scopus 로고
    • Neopterin and 7,8-dihydroneopterin modulate microbicidal effects of reactive oxygen and chlorine species on Escherlchia coli
    • Wede I, Semenitz E, Wachter H, Fuchs D: Neopterin and 7,8-dihydroneopterin modulate microbicidal effects of reactive oxygen and chlorine species on Escherlchia coli. Pteridines 7: 64-65, 1996.
    • (1996) Pteridines , vol.7 , pp. 64-65
    • Wede, I.1    Semenitz, E.2    Wachter, H.3    Fuchs, D.4
  • 34
    • 0029940215 scopus 로고    scopus 로고
    • Effects of pteridines on chloramine-T-induced growth inhibition in E. coli strains: Correlations with molecular structure
    • Horejsi R, Estelberger W, Mlekusch W, Moller R, Öttl K, Vrecko K, Reibnegger G: Effects of pteridines on chloramine-T-induced growth inhibition in E. coli strains: correlations with molecular structure. Free Radic Biol Med 21: 133-138, 1996.
    • (1996) Free Radic Biol Med , vol.21 , pp. 133-138
    • Horejsi, R.1    Estelberger, W.2    Mlekusch, W.3    Moller, R.4    Öttl, K.5    Vrecko, K.6    Reibnegger, G.7
  • 38
    • 0029562828 scopus 로고
    • Induction of inducible nitric oxide synthase expression by neopterin in vascular smooth muscle cells
    • Schobersberger W, Hoffmann G, Grote J, Wachter H, Fuchs D: Induction of inducible nitric oxide synthase expression by neopterin in vascular smooth muscle cells. FEBS Lett 377: 461-464, 1995.
    • (1995) FEBS Lett , vol.377 , pp. 461-464
    • Schobersberger, W.1    Hoffmann, G.2    Grote, J.3    Wachter, H.4    Fuchs, D.5
  • 39
  • 40
    • 0029586939 scopus 로고
    • Enhancing potency of neopterin toward B-16 melanoma cell damage induced by UV-A irradiation and its possible application for skin tumor treatment
    • Kojitna S, Icho T, Mori H, Arai T: Enhancing potency of neopterin toward B-16 melanoma cell damage induced by UV-A irradiation and its possible application for skin tumor treatment. Anticancer Res 15: 1975-1980, 1995.
    • (1995) Anticancer Res , vol.15 , pp. 1975-1980
    • Kojitna, S.1    Icho, T.2    Mori, H.3    Arai, T.4
  • 42
    • 0000733941 scopus 로고
    • A kinetic study of the autooxidation of tetrahydrobiopterin
    • Blair JA, Pearson AJ: A kinetic study of the autooxidation of tetrahydrobiopterin. Tetrahedron Lett 3: 203-204, 1973.
    • (1973) Tetrahedron Lett , vol.3 , pp. 203-204
    • Blair, J.A.1    Pearson, A.J.2
  • 44
    • 0027513924 scopus 로고
    • Effect of pteridine derivatives on intracellular calcium concentration in human monocytic cells
    • Wöll E, Weiss G, Fuchs D, Lang F, Wachter H: Effect of pteridine derivatives on intracellular calcium concentration in human monocytic cells. FEBS Lett 318: 249-252, 1993.
    • (1993) FEBS Lett , vol.318 , pp. 249-252
    • Wöll, E.1    Weiss, G.2    Fuchs, D.3    Lang, F.4    Wachter, H.5
  • 45
    • 0030483101 scopus 로고    scopus 로고
    • 7,8-Dihydroneopterin upregulates interferon-y promoter in T cells
    • Baier-Bitterlich G, Fuchs D, Wachter H: 7,8-Dihydroneopterin upregulates interferon-y promoter in T cells. Immunobiology 196: 350-355, 1996.
    • (1996) Immunobiology , vol.196 , pp. 350-355
    • Baier-Bitterlich, G.1    Fuchs, D.2    Wachter, H.3
  • 46
    • 0002433567 scopus 로고    scopus 로고
    • Advanced oxidation protein products, serum interleukin-6 and urinary neopterin as markers of cell mediated immunity in relation to proteinuria in diabetic nephropathy
    • Abou Deya SH, El-Lakany SA, Sharaki OA: Advanced oxidation protein products, serum interleukin-6 and urinary neopterin as markers of cell mediated immunity in relation to proteinuria in diabetic nephropathy. Clin Chem 44 (Suppl 6): A8
    • Clin Chem , vol.44 , Issue.6 SUPPL.
    • Abou Deya, S.H.1    El-Lakany, S.A.2    Sharaki, O.A.3
  • 47
    • 0023898932 scopus 로고
    • The ras gene family and human carcinogenesis
    • Bos J: The ras gene family and human carcinogenesis. Mutat Res 195: 255-271, 1988.
    • (1988) Mutat Res , vol.195 , pp. 255-271
    • Bos, J.1
  • 49
    • 0025122267 scopus 로고
    • Mutagenesis by hydrogen peroxide treatment of mammalian cells
    • Moraes EC, Keyse SM, Tyrell RM: Mutagenesis by hydrogen peroxide treatment of mammalian cells. Carcinogenesis 11: 283-293, 1990.
    • (1990) Carcinogenesis , vol.11 , pp. 283-293
    • Moraes, E.C.1    Keyse, S.M.2    Tyrell, R.M.3
  • 50
    • 0028897321 scopus 로고
    • Differential effects of superoxide, hydrogen peroxide, and hydroxyl radical on intracellular calcium in human endothelial cells
    • Dreher D, Junod AF: Differential effects of superoxide, hydrogen peroxide, and hydroxyl radical on intracellular calcium in human endothelial cells. J Cell Physiol 162: 147-153, 1995.
    • (1995) J Cell Physiol , vol.162 , pp. 147-153
    • Dreher, D.1    Junod, A.F.2
  • 52
    • 0024461627 scopus 로고
    • Translocation and enhancement of phosphoryltransferase activity of proteinkinase C following exposure in mouse epidermal cells to oxidants
    • Larsen R, Cerutti P: Translocation and enhancement of phosphoryltransferase activity of proteinkinase C following exposure in mouse epidermal cells to oxidants. Cancer Res 49: 5627-5632, 1989.
    • (1989) Cancer Res , vol.49 , pp. 5627-5632
    • Larsen, R.1    Cerutti, P.2
  • 53
    • 0025852479 scopus 로고
    • Modulation of transcription factor NF-kappaB binding activity by oxidation-reduction in vitro
    • Toledano MD, Leonard WJ: Modulation of transcription factor NF-kappaB binding activity by oxidation-reduction in vitro. Proc Natl Acad Sci USA 88: 4328-4332, 1991.
    • (1991) Proc Natl Acad Sci USA , vol.88 , pp. 4328-4332
    • Toledano, M.D.1    Leonard, W.J.2
  • 54
    • 0028176651 scopus 로고
    • Oxidative stress as a mediator of apoptosis
    • Buttke TM, Sandstrom PA: Oxidative stress as a mediator of apoptosis. Immunol Today 15: 7-10, 1994.
    • (1994) Immunol Today , vol.15 , pp. 7-10
    • Buttke, T.M.1    Sandstrom, P.A.2
  • 55
    • 0029918901 scopus 로고    scopus 로고
    • Role of oxygen free radicals in cancer development
    • Dreher D, Junod AF: Role of oxygen free radicals in cancer development. Eur J Cancer 32: 30-38, 1996.
    • (1996) Eur J Cancer , vol.32 , pp. 30-38
    • Dreher, D.1    Junod, A.F.2
  • 56
    • 0026035117 scopus 로고
    • Inflammation and oxidative stress in carcinogenesis
    • Cerutti PA, Trump PF: Inflammation and oxidative stress in carcinogenesis. Cancer Cells 3: 1-7, 1991.
    • (1991) Cancer Cells , vol.3 , pp. 1-7
    • Cerutti, P.A.1    Trump, P.F.2
  • 57
    • 0027171266 scopus 로고
    • Oxidants, antioxidants, and the degenerative diseases of aging
    • USA
    • Ames NB, Shigenaga MK, Hagen TM: Oxidants, antioxidants, and the degenerative diseases of aging. Proc Natl Acad Sci (USA) 90: 7915-7922, 1993.
    • (1993) Proc Natl Acad Sci , vol.90 , pp. 7915-7922
    • Ames, N.B.1    Shigenaga, M.K.2    Hagen, T.M.3
  • 59
    • 0026616876 scopus 로고
    • Induction of Th 1 and Th 2 responses: A key role for the 'natural' immune response?
    • Romagnani S: Induction of Th 1 and Th 2 responses: a key role for the 'natural' immune response? Immunol Today 13: 103-108, 1992.
    • (1992) Immunol Today , vol.13 , pp. 103-108
    • Romagnani, S.1
  • 60
    • 0021815478 scopus 로고
    • Abrogation of metastatic properties of tumor cells by de novo expression of H-2K antigens following H-2 gene transfection
    • Wallich R, Bulbuc N, Hammerling GJ, Katzav S, Segal S, Feldman M: Abrogation of metastatic properties of tumor cells by de novo expression of H-2K antigens following H-2 gene transfection. Nature 315: 301-305, 1985.
    • (1985) Nature , vol.315 , pp. 301-305
    • Wallich, R.1    Bulbuc, N.2    Hammerling, G.J.3    Katzav, S.4    Segal, S.5    Feldman, M.6
  • 61
    • 0025971703 scopus 로고    scopus 로고
    • The role of tumor-derived cytokines on the immune system of mice bearing a mammary adenocarcinoma, I: Induction of regulatory macrophages in normal mice by the in vivo administration of rGM-CSF
    • Fu YX, Watson GA, Kasahara M, Lopez DM: The role of tumor-derived cytokines on the immune system of mice bearing a mammary adenocarcinoma, I: induction of regulatory macrophages in normal mice by the in vivo administration of rGM-CSF. J Immunol 146: 783-789.
    • J Immunol , vol.146 , pp. 783-789
    • Fu, Y.X.1    Watson, G.A.2    Kasahara, M.3    Lopez, D.M.4
  • 62
    • 0019156135 scopus 로고
    • Shedding from normal and cancer cell surface
    • Black PH: Shedding from normal and cancer cell surface. N Engl J Med 303: 1415-1419, 1980.
    • (1980) N Engl J Med , vol.303 , pp. 1415-1419
    • Black, P.H.1
  • 63
    • 0026057052 scopus 로고
    • Antigen shedding vs development of natural suppressor cells as mechanism of tumor escape in mice bearing Ehrlich tumor
    • Vinuela JE, Rodriguez R, Gil J, Coll J, Dela Concha EG, Subiza JL: Antigen shedding vs development of natural suppressor cells as mechanism of tumor escape in mice bearing Ehrlich tumor. Int J Cancer 47: 86-91, 1991.
    • (1991) Int J Cancer , vol.47 , pp. 86-91
    • Vinuela, J.E.1    Rodriguez, R.2    Gil, J.3    Coll, J.4    Dela Concha, E.G.5    Subiza, J.L.6
  • 64
    • 0022332785 scopus 로고
    • Down-regulation of the anti-tumor immune response
    • North RJ: Down-regulation of the anti-tumor immune response. Adv Cancer Res 45: 1-43, 1985.
    • (1985) Adv Cancer Res , vol.45 , pp. 1-43
    • North, R.J.1
  • 66
    • 0027752672 scopus 로고
    • Serum soluble tumor necrosis factor receptor 55 is increased in patients with haematological neoplasias and is associated with immune activation and weight loss
    • Denz H, Orth B, Weiss G, Gallati H, Hermann R, Huber P, Wachter H, Fuchs D: Serum soluble tumor necrosis factor receptor 55 is increased in patients with haematological neoplasias and is associated with immune activation and weight loss. Eur J Cancer 29A: 2232-2235, 1993.
    • (1993) Eur J Cancer , vol.29 A , pp. 2232-2235
    • Denz, H.1    Orth, B.2    Weiss, G.3    Gallati, H.4    Hermann, R.5    Huber, P.6    Wachter, H.7    Fuchs, D.8
  • 67
    • 0024835226 scopus 로고
    • Endogenous release of interferon-gamma and diminished response of peripheral blood mononuclear cells to antigenic stimulation
    • Fuchs D, Malkovsky M, Reibnegger G, Werner ER, Forni G, Wachter H: Endogenous release of interferon-gamma and diminished response of peripheral blood mononuclear cells to antigenic stimulation. Immunol Lett 23: 103-108, 1989/1990.
    • (1989) Immunol Lett , vol.23 , pp. 103-108
    • Fuchs, D.1    Malkovsky, M.2    Reibnegger, G.3    Werner, E.R.4    Forni, G.5    Wachter, H.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.