Electrochemical detection of gene expression in tumor samples: Overexpression of Rak nuclear tyrosine kinase

Bioconjugate Chemistry

Volumn 13, Issue 2, 2002, Pages 172-176

  Armistead, Paul M ^a   Thorp, H Holden ^a  

^a The University of North Carolina at Chapel Hill   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

AMINO ACIDS; CHEMICAL DETECTION; ELECTROPHORESIS; ENZYMES; GENE EXPRESSION; INDIUM COMPOUNDS; POLYMERASE CHAIN REACTION; TIN OXIDES; TUMORS;

ABSOLUTE QUANTIFICATION; BREAST TISSUES; CHEMICALLY AMPLIFIED; ELECTROCHEMICAL DETECTION; GENES EXPRESSION; OVEREXPRESSIONS; PCR PRODUCTS; TISSUE SAMPLES; TUMOR SAMPLES; TYROSINE KINASE;

METAL COMPLEXES;

FRK PROTEIN, HUMAN; MESSENGER RNA; PROTEIN TYROSINE KINASE; RNA; TUMOR PROTEIN;

ARTICLE; BREAST TUMOR; ELECTROCHEMISTRY; ENZYMOLOGY; FEMALE; GENE EXPRESSION REGULATION; GENETICS; HUMAN; METABOLISM; METHODOLOGY; NUCLEOTIDE SEQUENCE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION;

BASE SEQUENCE; BREAST NEOPLASMS; ELECTROCHEMISTRY; FEMALE; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; NEOPLASM PROTEINS; PROTEIN-TYROSINE KINASES; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; RNA, MESSENGER; RNA, NEOPLASM;

EID: 0036009621     PISSN: 10431802     EISSN: None     Source Type: Journal    
DOI: 10.1021/bc000129y     Document Type: Article

References (33)

1. Defective regulation of phosphatidylinositol-3-kinase gene expression in skeletal muscle and adipose tissue of noninsulin-dependent diabetes mellitus patients
2. Quantitative decrease in syaptophysin message expression and increase in cathepsin D message expression in Alzheimer disease neurons containing neurofibrillary tangles
3. MYCN protein expression as a predictor of neuroblastoma prognosis
4. PED/PEA-15 gene controls glucose transport and is overexpressed in type 2 diabetes mellitus
5. Temporal cortex synaptophysin mRNA is reduced in Alzheimer's disease and is negatively correlated with the severity of dementia
6. NF-kappa B is activated and ICAM-1 gene expression is upregulated during reoxygenation of human brain endothelial cells
7. The transcription factor interferon regulatory factor 1 is expressed after cerebral ischemia and contributes to ischemic brain injury
8. A model-based approach for assessing in vivo combination therapy interactions
9. Studies of the HER-2/neu Proto-oncogene in human breast and ovarian cancer
10. Human breast cancer: Correlation of relpase and survival with amplificaiton of the HER-2/neu Oncogene
11. High expression of cyclin E and G1 CDK and loss of function of p57KIP are involved in proliferation of malignant sporadic adrencortical tumors
12. A potential role for protease nexin 1 in the pathogenesis of scleroderma
13. Nonisotopic quantitation of mRNA using a novel RNase protection assay: Measurement of erbB-2 mRNA in tumor cell lines
14. Quantitation of mRNA by the polymerase chain reaction
15. Competitive reverse transcription/polymerase chain reaction for the quantification of p53 and mdm2 mRNA expression
16. Quantification of c-erbB-2 expression in breast cancer by competitive RT-PCR
17. Exploring the metabolic and genetic control of gene expression on a genomic scale
18. Quantitative monitoring of gene expression patterns with a complementary DNA microarray
19. Cutting out the middleman: DNA biosensors based on electrochemical oxidation
20. Modification of electrodes with dicarboxylate self-assembled monolayers for attachment and detection of nucleic acids
21. Probing biomolecule recognition with electron transfer: Electrochemical sensors for DNA hybridization
22. Electrochemical measurement of the solvent accesibility of nucleobases using electron transfer between DNA and metal complexes
23. DNA electrochemical biosensor for the detection of short DNA sequences related to the human immunodeficiency virus
24. Voltammetric DNA biosensor for cystic fibrosis based on a modified carbon paste electrode
25. Sequence-specific gene detection with a gold electrode modified with DNA probes and an electrochemically active dye
26. Single-base mismatch detection based on charge transduction through DNA
27. Electrochemical measurement of the solvent accessibility of nucleobases using electron-transfer between DNA and metal complexes
28. DNA diagnostics using electronic detection
29. Rak, a novel nuclear tyrosine kinase expressed in epithelial cells
30. Adsorption and redox thermodynamics of strongly adsorbed cytochrome c on tin oxide electrodes
31. A commentary on the practical applications of competitive PCR
32. Competitive reverse transcriptase-PCR: An improved method for determination of c-erbB-2 gene expression