Microarray identifies cyclooxygenase-2-dependent modulation of insulin-like growth factor binding protein-3 in non-small cell lung cancer cells

Chest

Volumn 121, Issue 3, 2002, Pages 29S-30S

  Põld, Mehis ^a   Dohadwala, M ^a   Luo, J ^a   Lin, Y ^a   Dubinett, S ^a  

^a CHS   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CYCLOOXYGENASE 2; MESSENGER RNA; SOMATOMEDIN B; SOMATOMEDIN BINDING PROTEIN 3; SOMATOMEDIN C; ISOENZYME; MEMBRANE PROTEIN; PROSTAGLANDIN SYNTHASE; PTGS2 PROTEIN, HUMAN;

CANCER CELL; CANCER INHIBITION; CARCINOGENICITY; CELL LINE; CONFERENCE PAPER; CORRELATION ANALYSIS; DNA MICROARRAY; ENZYME ANALYSIS; ENZYME LINKED IMMUNOSORBENT ASSAY; GENE EXPRESSION; HUMAN; LUNG ADENOCARCINOMA; LUNG NON SMALL CELL CANCER; MITOGENICITY; PRIORITY JOURNAL; PROTEIN CONTENT; PROTEIN EXPRESSION; SOLUBILITY; ADENOCARCINOMA; ARTICLE; CELL CULTURE; GENE EXPRESSION REGULATION; GENETICS; LUNG TUMOR; METABOLISM; PHYSIOLOGY;

ADENOCARCINOMA; CARCINOMA, NON-SMALL-CELL LUNG; CYCLOOXYGENASE 2; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; INSULIN-LIKE GROWTH FACTOR BINDING PROTEIN 3; ISOENZYMES; LUNG NEOPLASMS; MEMBRANE PROTEINS; OLIGONUCLEOTIDE ARRAY SEQUENCE ANALYSIS; PROSTAGLANDIN-ENDOPEROXIDE SYNTHASES; RNA, MESSENGER; TUMOR CELLS, CULTURED;

EID: 0036006132     PISSN: 00123692     EISSN: None     Source Type: Journal    
DOI: 10.1378/chest.121.3_suppl.29S     Document Type: Conference Paper

References (16)

1. Interferon-γ and interleukin 4 inhibit interleukin 1 beta-induced delayed prostaglandin E(2) generation through suppression of cyclooxygenase-2 expression in human fibroblasts
2. Differential regulation of cyclo-oxygenase-2 (COX-2) mRNA stability by interleukin-1 β (IL-1 β) and tumor necrosis factor-α (TNF-α) in human in vitro differentiated macrophages
3. Synergistic induction of cyclo-oxygenase-2 by transforming growth factor-β1 and epidermal growth factor inhibits apoptosis in epithelial cells
4. TGF-β1 stimulates IL-8 release, COX-2 expression, and PGE(2) release in human airway smooth muscle cells
5. Enhancement of prostaglandin E2 production by epidermal growth factor requires the coordinate activation of cytosolic phospholipase A2 and cyclo-oxygenase-2 in human squamous carcinoma A431 cells
6. Specific inhibition of cyclo-oxygenase-2 restores antitumor reactivity by altering the balance of IL-10 and IL-12 synthesis
7. Non-small cell lung cancer cyclo-oxygenase-2-dependent regulation of cytokine balance in lymphocytes and macrophages: Up-regulation of interleukin-10 and down-regulation of interleukin-12 production
8. Alterations in cellular adhesion and apoptosis in epithelial cells overexpressing prostaglandin endoperoxide synthase 2
9. Blockade of cyclo-oxygenase-2 inhibits proliferation and induces apoptosis in human pancreatic cancer cells
10. Antiangiogenic and antitumor activities of cyclo-oxygenase-2 inhibitors
11. Inhibition of cyclo-oxygenase-2 suppresses angiogenesis and the growth of prostate cancer in vivo
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14. Insulin-like growth factor-binding protein-3 modulates expression of Bax and Bcl-2 and potentiates p53-independent radiation-induced apoptosis in human breast cancer cells
15. Transfection of human insulin-like growth factor-binding protein-3 gene inhibits cell growth and tumorigenicity: A cell culture model for lung cancer
16. Increased p53-dependent apoptosis by the insulin-like growth factor binding protein IGFBP-3 in human colonic adenoma-derived cells