Mutations within the putative active site of heterodimeric deoxyguanosine kinase block the allosteric activation of the deoxyadenosine kinase subunit

Journal of Biochemistry and Molecular Biology

Volumn 35, Issue 2, 2002, Pages 244-247

  Park, Inshik ^a   Ives, David H ^b  

^a Dong A University   (South Korea)

^b OHIO STATE UNIVERSITY   (United States)

Author keywords

Deoxyadenosine kinase; Deoxyguanosine kinase; Lactobacillus acidophilus; Site directed mutation

Indexed keywords

LACTOBACILLUS ACIDOPHILUS;

BACTERIAL DNA; DEOXYGUANOSINE KINASE; PHOSPHOTRANSFERASE; PROTEIN SUBUNIT;

ALLOSTERISM; AMINO ACID SEQUENCE; ARTICLE; CHEMISTRY; DIMERIZATION; ENZYME ACTIVE SITE; ENZYMOLOGY; GENETICS; LACTOBACILLUS ACIDOPHILUS; METABOLISM; NUCLEOTIDE SEQUENCE; SEQUENCE HOMOLOGY; SITE DIRECTED MUTAGENESIS;

ALLOSTERIC REGULATION; AMINO ACID SEQUENCE; BASE SEQUENCE; CATALYTIC DOMAIN; DIMERIZATION; DNA, BACTERIAL; LACTOBACILLUS ACIDOPHILUS; MUTAGENESIS, SITE-DIRECTED; PHOSPHOTRANSFERASES (ALCOHOL GROUP ACCEPTOR); PROTEIN SUBUNITS; SEQUENCE HOMOLOGY, AMINO ACID;

EID: 0036004561     PISSN: 12258687     EISSN: 12258687     Source Type: Journal    
DOI: 10.5483/bmbrep.2002.35.2.244     Document Type: Article

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