Relative hydrophobicity of amino acid residues in homooligopeptides as measured by aqueous two-phase partitioning

Journal of Peptide Research

Volumn 59, Issue 6, 2002, Pages 277-282

  Gulyaeva, N ^a   Zaslavsky, A ^a   Chait, A ^a   Zaslavsky, B ^a  

^a Analiza Inc   (United States)

Author keywords

Amino acids; Aqueous two phase partitioning; Homooligopeptides; Hydrophobicity; Lipophilicity; Partition coefficient

Indexed keywords

OLIGOPEPTIDE; SODIUM DIHYDROGEN PHOSPHATE; AMINO ACID; SOLVENT;

AMINO ACID COMPOSITION; AMINO ACID TRANSPORT; AQUEOUS SOLUTION; ARTICLE; CONFORMATIONAL TRANSITION; DERIVATIZATION; HYDROPHOBICITY; LIPOPHILICITY; MEASUREMENT; NONHUMAN; PARTITION COEFFICIENT; PRIORITY JOURNAL; QUANTITATIVE STRUCTURE ACTIVITY RELATION; AMINO ACID SEQUENCE; CHEMISTRY;

AMINO ACID SEQUENCE; AMINO ACIDS; HYDROPHOBICITY; OLIGOPEPTIDES; QUANTITATIVE STRUCTURE-ACTIVITY RELATIONSHIP; SOLVENTS; SUPPORT, U.S. GOV'T, P.H.S.;

EID: 0036001490     PISSN: 1397002X     EISSN: None     Source Type: Journal    
DOI: 10.1034/j.1399-3011.2002.02997.x     Document Type: Article

References (21)

1. Recognizing molecules with drug-like properties
2. Hydrophobic contribution constants of amino acid residues to the hydrophobicities of oligopeptides
3. How structural features influence the biomembrane permeability of peptides
4. Solvation energies of amino acid side chains and backbone in a family of host-guest pentapeptides
5. Strategies toward predicting peptide cellular permeability from computed molecular descriptors
6. Lipophilicity of amino acids
7. Hydrophobicity regained
8. Relative hydrophobicity of organic compounds measured by partitioning in aqueous two-phase systems
9. Measurement of the relative hydrophobicity of organic compounds without organic solvent. Effects of salt composition and pH on organic acids and non-ionic compounds
10. Measurement of relative hydrophobicity of amino acid side-chains by partition in an aqueous two-phase polymeric system: Hydrophobicity scale for non-polar and ionogenic side-chains
11. Peptides partitioning in an aqueous dextran-polyethylene glycol two-phase system
12. Partition of dipeptides in aqueous polymer two-phase systems as a function of pH in the presence of salts
13. Peptide hydrophobicity and partitioning in poly(ethylene glycol)/magnesium sulfate aqueous two-phase systems
14. Effects of amino acid sequence on the partition of peptides in aqueous two-phase system
15. Reversing the amino acid sequence of a dipeptide changes its partition in an aqueous two-phase system
16. Substitutions of surface amino acid residues of cutinase probed by aqueous two-phase partitioning
17. Hydrophobicity of oligopeptides having un-ionized side chains
18. Correlation of physicochemical parameters to the hydrophobic contribution constants of amino acid residues in small peptides