Relaxation kinetics and the glassiness of proteins: The case of bovine pancreatic trypsin inhibitor

Biophysical Journal

Volumn 83, Issue 2, 2002, Pages 699-705

  Baysal, Canan ^a   Atilgan, Ali Rana ^b  

^a SABANCI UNIVERSITY   (Turkey)

^b BOGAZICI UNIVERSITY   (Turkey)

Author keywords

[No Author keywords available]

Indexed keywords

APROTININ; PROTEIN;

ARTICLE; DECOMPOSITION; ENERGY; ENTROPY; HYDROPHILICITY; HYDROPHOBICITY; KINETICS; MOLECULAR DYNAMICS; PROTEIN ANALYSIS; PROTEIN CONFORMATION; SIMULATION; TEMPERATURE; TEMPERATURE DEPENDENCE; ALGORITHM; ANIMAL; BIOPHYSICS; CATTLE; CHEMISTRY; PROTEIN FOLDING;

BOVINAE;

ALGORITHMS; ANIMALS; APROTININ; BIOPHYSICS; CATTLE; ENTROPY; KINETICS; PROTEIN CONFORMATION; PROTEIN FOLDING; PROTEINS; TEMPERATURE;

EID: 0035996982     PISSN: 00063495     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0006-3495(02)75201-6     Document Type: Article

References (51)

1. Rattle: A "velocity" version of the shake algorithm for molecular dynamics calculations
2. Formation of glasses from liquids and biopolymers
3. Role of interfacial water in the molecular dynamics simulated dynamical transition of plastocyanin
4. Anisotropy of fluctuation dynamics of proteins with an elastic network model
5. Direct evaluation of thermal fluctuations in proteins using a single parameter harmonic potential
6. Collective dynamics of HIV-1 reverse transcriptase: Examination of flexibility and enzyme function
7. Coordination topology and stability for the native and binding conformers of chymotrypsin inhibitor 2
8. Elucidating the structural mechanisms for biological activity of the chemokine family
9. Molecular dynamics analysis of coupling between librational motions and isomeric jumps in chain molecules
10. The Protein Data Bank
11. Protein flexibility from the dynamical transition: A force constant analysis
12. Glasslike dynamical behavior of the plastocyanin hydration water
13. Locally accessible conformations of proteins: Multiple molecular dynamics simulations of crambin
14. Residue depth: A novel parameter for the analysis of protein structure and stability
15. Enzyme activity below the dynamical transition at 220 K
16. Structure and energetics of ligand binding to proteins: E. coli dihydrofolate reductase-trimethoprim, a drug-receptor system
17. Soft matter
18. Supercoled liquids and the glass transition
19. Single-molecule studies of heterogeneous dynamics in polymer melts near the glass transition
20. Dynamics of proteins predicted by molecular dynamics simulations and analytical approaches: Application to a-amylase inhibitor
21. Temperature effects on protein motions: A molecular dynamics study of RNase-Sa
22. Single molecules rock and roll near the glass transition
23. Dynamics and function of proteins: The search for general concepts
24. The energy landscapes and motions of proteins
25. Biological physics
26. The protein-glass analogy: Some insights from homopeptide comparisons
27. Theorie des elektrischen. Rückstandes in der leidener flasche
28. Microscopic origins of entropy, heat capacity and the glass transition in proteins
29. Thermal motions in bacteriorhodopsin at different hydration levels studied by neutron scattering: Correlation with kinetics and light-induced conformational changes
30. Protein normal-mode dynamics: Trypsin inhibitor, crambin, ribonuclease and lysozyme
31. Energetics of protein structure
32. Effect of temperature and hydration on protein fluctuations: Molecular dynamics simulation of Cu, Zn superoxide dismutase at six different temperatures. Comparison with neutron scattering data
33. A molecular dynamics method for simulations in the canonical ensemble
34. Glassy transition in a disordered model for RNA secondary structure
35. Biological water at the protein surface: Dynamical solvation probed directly with femtosecond resolution
36. Dynamics of different functional parts of bacteriorhodopsin: H-2H labeling and neutron scattering
37. Supercooled water and the kinetic glass transition
38. Dynamics of myoglobin: Comparison of simulation results with neutron scattering spectra
39. Internal mobility of the basic pancreatic trypsin inhibitor in solution: A comparison of NMR spin relaxation measurements and molecular dynamics simulations
40. The Kauzmann paradox revisited
41. Amplitudes and frequencies of protein dynamics: Analysis of discrepancies between neutron scattering and molecular dynamics simulations
42. Molecular dynamics of solid-state lysozyme as affected by glycerol and water: A neutron scattering study
43. The inverse relationship between protein dynamics and thermal stability
44. Solvent mobility and the protein "glass" transition
45. Non-symmetrical dielectric relaxation behavior arising from a simple empirical decay function
46. Structure of bovine pancreatic trypsin inhibitor. Results of joint neutron and x-ray refinement of crystal form II
47. Identifying the adaptive mechanism in globular proteins: Fluctuations in densely packed regions manipulate flexible parts
48. How soft is a protein? A protein dynamics force constant measured by neutron scattering
49. Native proteins are surfacemolten solids: Application of the Lindemann criterion for the solid versus liquid state