Dinitrobenzene-mediated production of peroxynitrite by neuronal nitric oxide synthase

Chemical Research in Toxicology

Volumn 15, Issue 7, 2002, Pages 927-934

  Miller, R Timothy ^a  

^a UNIVERSITY OF KENTUCKY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1,3 DINITROBENZENE; AROMATIC NITRO COMPOUND; CITRULLINE; CYTOCHROME P450 REDUCTASE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; NITROBENZENE DERIVATIVE; PEROXYNITRITE; RADICAL; SUPEROXIDE; ARGININE; NICOTINAMIDE ADENINE DINUCLEOTIDE PHOSPHATE; PEROXYNITROUS ACID;

ARTICLE; DIFFUSION; ELECTRON TRANSPORT; ENZYME ACTIVITY; NERVE CELL; REACTION TIME; ANIMAL; BIOSYNTHESIS; CATALYSIS; CHEMISTRY; DRUG EFFECT; ENZYMOLOGY; ISOMERISM; METABOLISM; RAT;

ANIMAL; ARGININE; CATALYSIS; CITRULLINE; DINITROBENZENES; ELECTRON TRANSPORT; ISOMERISM; NADP; NEURONS; NITRIC OXIDE; NITRIC-OXIDE SYNTHASE; PEROXYNITROUS ACID; RATS; SUPEROXIDES; SUPPORT, NON-U.S. GOV'T; ANIMALS; NITRIC OXIDE SYNTHASE;

EID: 0035996331     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx020016y     Document Type: Article

References (49)

1. Cloned and expressed nitric oxide synthase structurally resembles cytochrome P450 reductase
2. Precise distribution of neuronal nitric oxide synthase mRNA in the rat brain revealed by nonradioisotopic in situ hybridization
3. Evidence for a bidomain structure of constitutive cerebellar nitric oxide synthase
4. Endothelium-derived relaxing factor produced and released from artery and vein is nitric oxide
5. Nitric oxide release accounts for the biological activity of endotheliumderived relaxing factor
6. Studies on relaxation of rabbit aorta by sodium nitrite: The basis for the proposal that the acid-activatable inhibitory factor from bovine retractor penis is inorganic nitrite and the endothelium-derived relaxing factor is nitric oxide
7. Endothelium-derived relaxing factor release on activation of NMDA receptors suggests role as intercellular messenger in the brain
8. Cloned, expressed rat cerebellar nitric oxide synthase contains stoichiometric amounts of heme, which binds carbon monoxide
9. Nitric oxide synthase is a cytochrome P450 type hemoprotein
10. Spectral characterization of brain and macrophage nitric oxide synthases
11. Brain nitric oxide synthase is a heme protein
12. Isolation of nitric oxide synthase, a calmodulin-requiring enzyme
13. Calmodulin controls neuronal nitric-oxide synthase by a dual mechanism
14. Involvement of the reductase domain of neuronal nitric oxide synthase in superoxide anion production
15. Inhibition of nitric oxide formation by neuronal nitric oxide synthase by quinones: Nitric oxide synthase as a quinone reductase
16. Bioreductive mechanisms
17. Purified liver microsomal NADPH-cytochrome P450 reductase
18. Rapid kinetic studies of electron transfer in the three isoforms of nitric oxide synthase
19. Geometric relationship between the nicotinamide and isoalloxazine rings in NADPH-cytochrome P450 oxidoreductase: Implications for the classification of evolutionarily and functionally related flavoproteins
20. Characterization of hydride transfer to flavin adenine dinucleotide in neuronal nitric oxide synthase reductase domain: Geometric relationship between the nicotinamide and isoalloxazine rings
21. Inhibition of nitric oxide synthase by antineoplastic anthracyclines
22. Biosynthesis of nitric oxide from L-arginine: A pathway for the regulation of cell function and communication
23. Endothelium derived nitric oxide: Actions and properties
24. Neuronal nitric oxide synthase selfinactivates by forming a ferrous-nitrosyl complex during aerobic catalysis
25. Nitric oxide binding to the heme of neuronal nitric-oxide synthase links its activity to changes on oxygen tension
26. The reaction of NO with superoxide
27. 1,3-Dinitrobenzene-induced encephalopathy in rats
28. Metabolism of dinitrobenzenes by rat isolated hepatocytes
29. Metabolism and excretion of dinitrobenzenes by male Fischer-344 rats
30. High-level expression of functional rat neuronal nitric oxide synthase in Escherichia coli
31. The stimulatory effects of Hofmeister ions on the activities of neuronal nitric-oxide synthase
32. Dichlorodihydrofluorescein and dihydrorhodamine 123 are sensitive indicators of peroxynitrite in vitro: Implications for intracellular measurement of reactive nitrogen and oxygen species
33. A quantitative test for superoxide radicals produced in biological systems
34. Determination of free amino groups in proteins by trinitrobenzenesulfonic acid
35. Assay of isoforms of E. coli-expressed nitric oxide synthase
36. Neurotoxic effects of fractionated diesel exhausts following microinjections in rat hippocampus and striatum
37. Neurotoxicity of 1,3,5-trinitrobenzene (TNB): Immunohistochemical study of cerebrovascular permeability
38. A critical review of the literature on nitrobenzene toxicity
39. Vascular factors in the neurotoxic damage caused by 1,3-dinitrobenzene in the rat
40. Early metabolic changes during m-dinitrobenzene neurotoxicity and the possible role of oxidative stress
41. Crystal structure of constitutive endothelial nitric oxide synthase: A paradigm for pterin function involving a novel metal center
42. The mechanism of action of superoxide dismutase from pulse radiolysis and electron paramagnetic resonance
43. Peroxynitrite, a cloaked oxidant formed by nitric oxide and superoxide
44. Peroxynitrite-mediated oxidation of dihydrorhodamine 123
45. Nitration and hydroxylation of phenolic compounds by peroxynitrite
46. Antibodies that recognize nitrotyrosine
47. Superoxide anion production from lucigenin: An electron spin resonance spin-trapping study
48. Endothelial nitric oxide synthase-dependent superoxide generation from adriamycin