Quantification of 2′-fluoro-2′-deoxyuridine and 2′-fluoro-2′-deoxycytidine in DNA and RNA isolated from rats and woodchucks using LC/MS/MS

Chemical Research in Toxicology

Volumn 15, Issue 7, 2002, Pages 922-926

  Richardson, Frank C ^a   Zhang, Chenghong ^b   Lehrman, S Russ ^c   Koc, Hasan ^d   Swenberg, James A ^d   Richardson, Katherine A ^e   Bendele, Raymond A ^a  

^a OSI PHARMACEUTICALS INC   (United States)

^b PFIZER INC   (United States)

^c NEKTAR THERAPEUTICS   (United States)

^d UNIVERSITY OF NORTH CAROLINA   (United States)

^e Molecular Experimental Design   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

2' FLUORO 2' DEOXYCYTIDINE; 2' FLUORO 2' DEOXYURIDINE; 2' FLUOROPYRIMIDINE; CYTIDINE DERIVATIVE; DNA; NUCLEOSIDE; PYRIMIDINE DERIVATIVE; RNA; UNCLASSIFIED DRUG; URIDINE DERIVATIVE; 2'-FLUORO-2'-DEOXYCYTIDINE; DEOXYCYTIDINE; DRUG DERIVATIVE; FLOXURIDINE;

ANIMAL EXPERIMENT; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; KIDNEY; LIQUID CHROMATOGRAPHY; LIVER; MALE; MASS SPECTROMETRY; MUSCLE; NONHUMAN; QUANTITATIVE ANALYSIS; RAT; SPLEEN; TESTIS; TOXICITY TESTING; WOODCHUCK; ANIMAL; ANTIBODY SPECIFICITY; BIOSYNTHESIS; CHEMISTRY; ELECTROSPRAY MASS SPECTROMETRY; FISCHER 344 RAT; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; HYDROLYSIS; METABOLISM; SCIURIDAE;

ANIMALIA; MAMMALIA; MARMOTA MONAX;

ANIMALS; CHROMATOGRAPHY, HIGH PRESSURE LIQUID; DEOXYCYTIDINE; DNA; FLOXURIDINE; HYDROLYSIS; MALE; MARMOTA; ORGAN SPECIFICITY; RATS; RATS, INBRED F344; RNA; SPECTROMETRY, MASS, ELECTROSPRAY IONIZATION;

EID: 0035996329     PISSN: 0893228X     EISSN: None     Source Type: Journal    
DOI: 10.1021/tx020014d     Document Type: Article

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