An Evaluation of the Toxicities of 2' -Fluorouridine and 2'-Fluorocytidine-HCI in F344 Rats and Woodchucks (Marmota monax)

Toxicologic Pathology

Volumn 27, Issue 6, 1999, Pages 607-617

  Richardson, Frank C ^a   Tennant, Bud C ^a   Meyer, Denny J ^b   Richardson, Katherine A ^b   Mann, Peter C ^c   Mcginty, Gregory R ^d   Wolf, Julie L ^d   Zack, Philip M ^d   Bendele, Raymond A ^d  

^a Marmotech Inc   (United States)

^b Molecular Experimental Design   (United States)

^c EXPERIMENTAL PATHOLOGY LABORATORIES INC   (United States)

^d GILEAD SCIENCES   (United States)

Author keywords

aptamer; cytochrome c oxidase; intravenous; mtDNA; Nucleoside analogs

Indexed keywords

CITRATE SYNTHASE; CYTIDINE DERIVATIVE; CYTOCHROME C OXIDASE; FIALURIDINE; MITOCHONDRIAL DNA; NUCLEOSIDE ANALOG; URIDINE DERIVATIVE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; AUTOPSY; BONE MARROW; CELL INFILTRATION; CLINICAL CHEMISTRY; CONTROLLED STUDY; DNA DETERMINATION; ENZYME ACTIVITY; ENZYME ANALYSIS; FEMALE; HEMATOLOGY; HISTOLOGY; LYMPHOCYTE COUNT; MALE; MEAN CORPUSCULAR HEMOGLOBIN; MEAN CORPUSCULAR VOLUME; NONHUMAN; PRIORITY JOURNAL; RAT; SPLEEN; THYMUS; TOXICITY TESTING; URINALYSIS; WOODCHUCK;

ANIMALS; BICARBONATES; BODY WEIGHT; DEOXYCYTIDINE; DOSE-RESPONSE RELATIONSHIP, DRUG; ERYTHROCYTE INDICES; FEMALE; FLOXURIDINE; HEMATOCRIT; HEMATOLOGIC TESTS; LACTIC ACID; LYMPHOCYTE COUNT; MALE; MARMOTA; ORGAN SIZE; PORTAL SYSTEM; RATS; RATS, INBRED F344; SEX FACTORS; SPLEEN; THYMUS GLAND;

EID: 0032701241     PISSN: 01926233     EISSN: None     Source Type: Journal    
DOI: 10.1177/019262339902700601     Document Type: Article

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