Prostacyclin enhances the expression of LPS/INF-γ-induced nitric oxide synthase in human monocytes

Nephron

Volumn 91, Issue 3, 2002, Pages 391-398

  Plum, Jörg ^a   Huang, Chunmei ^a   Grabensee, Bernd ^a   Schrör, Karsten ^a   Meyer Kirchrath, Jutta ^a  

^a HEINRICH HEINE UNIVERSITY   (Germany)

Author keywords

Cicaprost; Inducible nitric oxide synthase; Peritonitis; Prostacyclin receptor (IP receptor); RT PCR

Indexed keywords

CICAPROST; CYCLIC AMP; GAMMA INTERFERON; LIPOPOLYSACCHARIDE; NITRIC OXIDE; NITRIC OXIDE SYNTHASE; PROSTACYCLIN; PROSTACYCLIN RECEPTOR; DRUG DERIVATIVE; INDUCIBLE NITRIC OXIDE SYNTHASE; MESSENGER RNA; NOS2A PROTEIN, HUMAN; PROSTAGLANDIN RECEPTOR;

ANALYTIC METHOD; ARTICLE; BLOOD; CELL STIMULATION; CONTROLLED STUDY; CULTURE MEDIUM; CYTOKINE PRODUCTION; DRUG SELECTIVITY; HUMAN; HUMAN CELL; MACROPHAGE; MEASUREMENT; MONOCYTE; NORMAL HUMAN; PERITONITIS; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SIGNAL DETECTION; CELL CULTURE; CYTOLOGY; DRUG EFFECT; GENETICS; METABOLISM;

CELLS, CULTURED; CYCLIC AMP; EPOPROSTENOL; HUMAN; INTERFERON TYPE II; LIPOPOLYSACCHARIDES; MONOCYTES; NITRIC OXIDE; NITRIC-OXIDE SYNTHASE; PERITONITIS; RECEPTORS, PROSTAGLANDIN; RNA, MESSENGER; HUMANS; NITRIC OXIDE SYNTHASE; NITRIC OXIDE SYNTHASE TYPE II; RECEPTORS, EPOPROSTENOL;

EID: 0035996175     PISSN: 00282766     EISSN: None     Source Type: Journal    
DOI: 10.1159/000064278     Document Type: Article

References (40)

1. Characteristics of long-term peritoneal dialysis patients
2. The influence of continuous ambulatory peritoneal dialysis connection technique on peritonitis rate and technique survival
3. Role of the peritoneal membrane in the control of inflammation in the peritoneal cavity
4. Peritoneal nitric oxide is a marker of peritonitis in patients on continuous ambulatory peritoneal dialysis
5. Human mononuclear phagocyte inducible nitric oxide synthase (iNOS): Analysis of iNOS mRNA, iNOS protein, biopterin, and nitric oxide production by blood monocytes and peritoneal macrophages
6. Nitrite generation in interleukin-4-treated human macrophage cultures does not involve the nitric oxide synthase pathway
7. On the expression of nitric oxide synthase by human macrophages: Why no NO?
8. Interferon (IFN)-α activation of human blood mononuclear cells in vitro and in vivo for nitric oxide synthase (NOS) type 2 mRNA and protein expression: Possible relationship of induced NOS2 to the anti-hepatitis C effects of IFN-α in vivo
9. Human monocytes are stimulated for nitric oxide release in vitro by some tumor cells but not by cytokines and lipopolysaccharide
10. Nitric oxide production by monocytes in alcoholic liver disease
11. Availability of tetrahydrobiopterin is not a factor in the inability to detect nitric oxide production by human macrophages
12. Nitric oxide in Tanzanian children with malaria: Inverse relationship between malaria severity and nitric oxide production/nitric oxide synthase type 2 expression
13. Increased expression of blood mononuclear cell nitric oxide synthase type 2 in rheumatoid arthritis patients
14. Nitric oxide production and inducible nitric oxide synthase expression in inflammatory arthritides
15. Inducible nitric oxide synthase in pulmonary alveolar macrophages from patients with tuberculosis
16. 2, cholera toxin and 8-bromo-cyclic AMP on lipopolysaccharide-induced gene expression of cytokines in human macrophages
17. 2 attenuation of sheep lung responses to endotoxin
18. An increase in intracellular cyclic AMP modulates nitric oxide production in IFN-gamma-treated macrophages
19. Cyclic AMP-elevating agents induce an inducible type of nitric oxide synthase in cultured vascular smooth muscle cells: Synergism with the induction elicited by inflammatory cytokines
20. Increasing cAMP attenuates induction of inducible nitric-oxide synthase in rat primary astrocytes
21. 2 and other cyclic AMP stimulants in J774 macrophages
22. 2 negatively modulates induction of nitric oxide synthase by interleukin 1
23. Co-induction of nitric oxide synthase and cyclooxygenase: Interactions between nitric oxide and prostanoids
24. Stimulation of peritoneal synthesis of vasoactive prostaglandins during peritonitis in patients on continuous ambulatory peritoneal dialysis
25. In vivo and in vitro effects of amino-acid-based and bicarbonate-buffered peritoneal dialysis solutions with regard to peritoneal transport and cytokines/prostanoids dialysate concentrations
26. 2 inhibits lipopolysaccharide-induced tumor necrosis factor-alpha generation
27. Gene expression of the human prostaglandin E receptor EP4 subtype: Differential regulation in monocytoid and lymphoid lineage cells by phorbol ester
28. Isolation of mononuclear cells and granulocytes from human blood: Isolation of mononuclear cells by one centrifugation, and of granulocytes by combining centrifugation and sedimentation at 1 g
29. Cytokine-induced nitric oxide generation by cultured astrocytoma cells involves Ca(++)-calmodulin-independent NO-synthase
30. Radioim-munoassay for cyclic nucleotides. I. Preparation of antibodies and iodinated cyclic nucleotides
31. The response of human peritoneal macrophages to stimulation with bacteria isolated from episodes of continuous ambulatory peritoneal dialysis-related peritonitis
32. Macrophages and mesothelial cells in bacterial peritonitis
33. 2 stimulated cAMP production by macrophages from endotoxin-tolerant rats
34. Transcriptional basis for hyporesponsiveness of the human inducible nitric oxide synthase gene to lipopolysaccharide/interferon-gamma
35. Inducible nitric oxide synthase (iNOS) expression in human monocytes triggered by β-endorphin through an increase in cAMP
36. Transcriptional regulation of inducible nitric oxide synthase in cultured neonatal rat cardiac myocytes
37. Two distinct signaling pathways trigger the expression of inducible nitric oxide synthase in rat renal mesangial cells
38. Nitric oxide production in peritoneal macrophages from peritoneal dialysis patients with bacterial peritonitis
39. Altered immune responses in mice lacking inducible nitric oxide synthase
40. Depletion of nitric oxide causes cell cycle alterations, apoptosis, and oxidative stress in pulmonary cells