Gene expression of the human prostaglandin E receptor EP4 subtype: Differential regulation in monocytoid and lymphoid lineage cells by phorbol ester

Journal of Molecular Medicine

Volumn 74, Issue 6, 1996, Pages 333-336

  Mori, K ^a   Tanaka, I ^a   Kotani, M ^a   Miyaoka, F ^a   Sando, T ^a   Muro, S ^a   Sasaki, Y ^a   Nakagawa, O ^a   Ogawa, Y ^a   Usui, T ^a   Ozaki, S ^a   Ichikawa, A ^a   Narumiya, S ^a   Nakao, K ^a  

^a KYOTO UNIVERSITY   (Japan)

Author keywords

cyclic AMP; EP4 subtype; phorbol myristate acetate; prostaglandin E receptor; THP 1

Indexed keywords

COMPLEMENTARY DNA; CYCLIC AMP; PHORBOL ESTER; PROSTAGLANDIN E; PROSTAGLANDIN E RECEPTOR;

ARTICLE; CONTROLLED STUDY; GENE EXPRESSION REGULATION; HUMAN; HUMAN CELL; IMMUNE SYSTEM; LYMPHOID CELL; MOLECULAR CLONING; MONOCYTE;

EID: 8944224022     PISSN: 09462716     EISSN: None     Source Type: Journal    
DOI: 10.1007/BF00207510     Document Type: Article

References (17)

1. Coleman RA, Smith WL, Narumiya S (1994) International union of pharmacology classification of prostanoid receptors: properties, distribution, and structure of the receptors and their subtypes. Pharm Rev 46:205-229
2. Coleman RA, Grix SP, Head SA, Louttit JB, Mallett A, Sheldrick RLG (1994) A novel inhibitory prostanoid receptor in piglet saphenous vein. Prostaglandins 47:151-168
3. Lewis GP (1983) Immunoregulatory activity of metabolites of arachidonic acid and their role in inflammation. Br Med Bull 39:243-248
4. 2 promotes IL-4 induced IgE and IgG1 synthesis. J Immunol 145:2644-2651
5. 2 regulates macrophage-derived tumor necrosis factor gene expression. J Biol Chem 263:5380-5384
6. 2 inhibits production of Th1 lymphokines but not of Th2 lymphokines. J Immunol 146:108-113
7. Nishizuka Y (1984) The role of protein kinase C in cell surface signal transduction and tumor promotion. Nature 308: 69.3-698
8. 2 subtype. Biochem Biophys Res Commun 200: 1329-1333
9. 2 subtype. J Biol Chem 268:7759-7762
10. 4 subtype. FEBS Lett 364:339-341
11. Sambrook J, Fritsch EF, Maniatis T (1989) Molecular cloning: a laboratory manual, 2nd edn. Cold Spring Harbor Laboratory, Cold Spring Harbor
12. 2 subtype. Mol Pharm 46:213-220
13. 2. Biochem Biophys Res Commun 197:263-270
14. 2 subtype. J Biol Chem 269:11873-11877
15. Tsuchiya S, Kobayashi Y, Goto Y, Okumura H, Nakae S, Konno T, and Tada K (1982) Induction of maturation in cultured human monocytic leukemia cells by a phorbol diester, Cancer Res 42:1530-1536
16. Sanduja SK, Mehta K, Xu XM, Hsu SM, Sanduja R, Wu KK (1991) Differentiation-associated expression of prostaglandin H and thromboxane A synthases in monocytoid leukemia cell lines. Blood 78:3178-3185
17. Smith CJ, Morrow JD, Roberts LJ II, Marnett LJ (1993) Differentiation of monocytoid THP-1 cells with phorhol ester induces expression of prostaglandin endoperoxide synthase-1 (COX-1). Biochem Biophys Res Commun 192:787-793