Transforming growth factor-β1 (TGF-β1): A potential recovery signal in the post-ischemic kidney

Renal Failure

Volumn 24, Issue 4, 2002, Pages 391-406

  Docherty, Neil G ^a   Pérez Barriocanal, Fernando ^a   Balboa, Nelida E ^a   López Novoa, José M ^a  

^a UNIVERSITY OF SALAMANCA   (Spain)

Author keywords

Acute renal failure; Acute tubular necrosis; Angiotensin II; ECM production; Hypoxia; TGF 1; Tubular recovery

Indexed keywords

ADENOSINE TRIPHOSPHATASE (POTASSIUM SODIUM); ANGIOTENSIN; CD31 ANTIGEN; COLLAGEN TYPE 4; FIBRONECTIN; GAMMA INTERFERON; NITRIC OXIDE SYNTHASE; PLATELET DERIVED GROWTH FACTOR; TRANSFORMING GROWTH FACTOR BETA1; ANGIOTENSIN II; TRANSFORMING GROWTH FACTOR BETA;

ACUTE KIDNEY FAILURE; ACUTE KIDNEY TUBULE NECROSIS; CELL DIFFERENTIATION; CELL PROLIFERATION; EXTRACELLULAR MATRIX; HUMAN; HYPOXIA; KIDNEY FIBROSIS; KIDNEY ISCHEMIA; KIDNEY TUBULE EPITHELIUM; NEGATIVE FEEDBACK; NONHUMAN; PRIORITY JOURNAL; REPERFUSION INJURY; REVIEW; ANIMAL; ISCHEMIA; KIDNEY; METABOLISM; PATHOPHYSIOLOGY; PHYSIOLOGY; UPREGULATION; VASCULARIZATION;

ANGIOTENSIN II; ANIMAL; HUMAN; ISCHEMIA; KIDNEY; KIDNEY FAILURE, ACUTE; REPERFUSION INJURY; SUPPORT, NON-U.S. GOV'T; TRANSFORMING GROWTH FACTOR BETA; UP-REGULATION; ANIMALS; HUMANS;

EID: 0035994226     PISSN: 0886022X     EISSN: None     Source Type: Journal    
DOI: 10.1081/JDI-120006767     Document Type: Review

References (70)

1. Current concepts on the pathophysiology of acute renal failure
2. Acute renal failure in the aged
3. Renal circulatory nephron function in experimental ARF
4. Protective effect of exogenous nitric oxide on the renal function and inflammatory response in a model of ischemia-reperfusion
5. 3 segments
6. Reversible hemodynamic defect in glomerular filtration rate after ischemic injury
7. The early phase of experimental acute renal failure. V. The influence of suppressing the renin-angiotensin system
8. Potential role of platelet activating factor in acute renal failure
9. A role for endothelin in the maintenance of postischemic acute renal failure
10. Renal adenosine a1 receptor binding characteristics and mRNA levels during the development of acute renal failure in the rat
11. Enhanced recovery from postischemic acute renal failure. Micropuncture studies in the rat
12. Role of growth factors in acute renal failure
13. Potential role of growth factors in the prophylaxis and treatment of acute renal failure
14. Epidermal growth factor in acute renal failure
15. Endogenous EGF as a potential renotrophic factor in ischemia-induced acute renal failure
16. Production and activation of hepatocyte growth factor in acute renal failure
17. Renal growth hormone-insulin-like growth factor-I system in acute renal failure
18. TGF-beta receptors and actions
19. TGF-β signaling from cell membrane to nucleus through Smad proteins
20. Transforming growth factor-beta 1 induces collagen IV gene expression in NIH-3T3 cells
21. Transcriptional activation of matrix genes by TGF-β1 in mesangial cells
22. Transforming growth factor β modulation of the alpha1 (IV) collagen gene in murine PT cells
23. Extracellular matrix related genes in kidney after ischemic injury: Potential role for TGF-β in repair
24. Angiotensin transforming growth factor β repair in the infarcted heart
25. Elevation of expression of Smads 2, 3 and 4, decorin and TGF-B in the chronic phase of myocardial infarct scar healing
26. Latent high molecular weight complex of TGF-β1
27. Association of the small latent transforming growth factor β with an eight cysteine repeat of its binding protein LTBP-1
28. Regulation of transforming growth factor beta activation through discrete sequences of thrombospondin
29. Autoantibodies produced by young Ipr mice carry transforming growth factor beta and suppress cytotoxic lymphocyte responses
30. Molecular and cell biology of TGF-β
31. TGF-beta family signal transduction in drosophila development: From Mad to Smads
32. Role of TGF-β1 in platelet-mediated cardioprotection during ischemia-reperfusion in isolated rat hearts
33. Transforming growth factor beta 1 preserves endothelial function after multiple brief coronary artery occlusions and reperfusion
34. Increased expression of TGF-β1 in brain tissue after ischemic stroke in humans
35. Transforming growth factor beta attenuates ischemia induced alterations in cerebrovascular reponses
36. Ischemic acute tubular necrosis induces an extensive local cytokine response. Evidence for induction of interferon gamma, transforming growth factor beta-1, granulocyte-macrophage colony stimulating factor, interleukin-2 and interleukin-10
37. Growth factor transcripts in rat renal transplants
38. Increased transforming growth factor-beta 1 expression in regenerating rat renal tubules following ischemic injury
39. Hypoxia augments cytokine (transforming growth factor-beta (TGF-β) and IL-1) induced vascular endothelial growth factor secretion by human synovial fibroblasts
40. Oxygen regulation of TGF-β1 mRNA in human hepatoma (HepG2) cells
41. Hypoxia up-regulates the synthesis of TGF-β1 by human dermal fibroblasts
42. Attenuation of renal ischemia-reperfusion injury in inducible nitric oxide synthase knockout mice
43. Renal ischemia in the rat stimulates glomerular nitric oxide synthesis
44. Functional requirement of the hypoxia response element in the activation of the inducible nitric oxide synthase promoter by the iron chelator desferroxamine
45. Regulation of hypoxic gene expression in yeast
46. Stimulation of autocrine PDGF AA-homodimer and transforming growth factor beta-1 in vascular smooth muscle cells
47. The renin system in hypertension: A research journey
48. Induction of PDGF a-chain and c-myc gene expressions by angiotensin II in cultured rat vascular smooth muscle cells
49. Vascular smooth muscle cell hypertrophy versus hyperplasia: Autocrine transforming growth factor beta-1 determines growth responses to angiotensin II
50. TGF-beta and angiotensin induced mesangial matrix protein secretion is mediated by protein kinase C
51. Association of TGF-beta signaling in angiotensin II induced PAI-1 mRNA up-regulation in mesangial cells: Role of PKC
52. Therapeutic advantage of converting enzyme inhibitors in arresting progressive renal disease associated with systemic hypertension in the rat
53. Pharmacologic control of angiotensin II ameliorates renal disease while reducing renal TGF-β in experimental mesangioproliferative glomerulonephritis
54. Acute renal failure after the use of angiotensin-converting enzyme inhibitors in patients without renal artery stenosis
55. Beneficial effect of verapamil added to chronic ace inhibitor treatment on renal function in hypertensive elderly patients
56. Acute renal failure from multiple myeloma precipitated by ACE inhibitors
57. Identification of Smad7 a TGF-β inducible antagonist of TGF-β signaling
58. Endoglin, a TGF-beta binding protein of endothelial cells, is the gene for hereditary hemorrhagic telangiectasia type 1
59. Endoglin is a component of the transforming growth factor beta receptor system in human endothelial cells
60. Regulated expression on human macrophages of endoglin an Arg-Gly-Asp-containing surface antigen
61. CD34+/CD105+ cells are enriched in primitive circulating progenitors residing in the G0 phase of the cell cycle and contain all bone marrow and cord blood CD34+/CD38low/-precursors
62. Identification of distinct epitopes of endoglin, an RGD-containing glycoprotein of endothelial cells, leukemic cells and syncytiotrophoblasts
63. Expression of endoglin mRNA and protein in human and rat mesangial cells and its up-regulation by TGF-β1
64. Expression of endoglin mRNA and protein in human vascular smooth muscle cells
65. Endoglin forms a heteromeric complex with the signaling receptors for transforming growth factor β
66. Endoglin modulates cellular responses to TGF-β1
67. Endoglin over-expression modulates cellular morphology, migration, and adhesion of mouse fibroblasts
68. Differences in osteopontin up-regulation between proximal and distal tubules after renal ischemia/reperfusion
69. Up-regulation of endoglin, a TGF-beta-binding protein, in rats with experimental renal fibrosis induced by renal mass reduction
70. Up-regulation of endoglin induced by unilateral ureteral ligation in rats