Up-regulation of endoglin, a TGF-β-binding protein, in rats with experimental renal fibrosis induced by renal mass reduction

Nephrology Dialysis Transplantation

Volumn 16, Issue SUPPL. 1, 2001, Pages 34-39

  Rodríguez Peña, Ana ^a   Prieto, Marta ^a   Duwel, Annette ^a   Rivas, Juan V ^a   Eleno, Nélida ^a   Pérez Barriocanal, Fernando ^a   Arévalo, Miguel ^a   Smith, Joshua D ^c   Vary, Calvin P H ^c   Bernabeu, Carmelo ^b   López Novoa, José M ^a  

^a UNIVERSITY OF SALAMANCA   (Spain)

^b CENTRO DE INVESTIGACIONES BIOLÓGICAS   (Spain)

^c Maine Medical Center Research Institute   (United States)

Author keywords

Chronic renal failure; Endoglin; Glomerulosclerosis; Renal mass reduction; Transforming growth factor ; Tubulo interstitial fibrosis

Indexed keywords

BINDING PROTEIN; ENDOGLIN; GLYCOPROTEIN; MEMBRANE PROTEIN; MESSENGER RNA; PROTEIN; TRANSFORMING GROWTH FACTOR BETA; TRANSFORMING GROWTH FACTOR BETA1; TRANSFORMING GROWTH FACTOR BETA3;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BINDING AFFINITY; CHRONIC KIDNEY FAILURE; CONTROLLED STUDY; DISEASE SEVERITY; EPITHELIUM; EXTRACELLULAR MATRIX; GLOMERULUS; HYPERTENSION; IMMUNOHISTOCHEMISTRY; KIDNEY BIOPSY; KIDNEY DISEASE; KIDNEY FIBROSIS; KIDNEY FUNCTION; KIDNEY INJURY; KIDNEY MASS; MALE; MEAN ARTERIAL PRESSURE; MEASUREMENT; NONHUMAN; NORTHERN BLOTTING; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN URINE LEVEL; RAT; REGULATORY MECHANISM; TIME; URINARY EXCRETION; VASCULAR ENDOTHELIUM; WESTERN BLOTTING;

EID: 0035007597     PISSN: 09310509     EISSN: None     Source Type: Journal    
DOI: 10.1093/ndt/16.suppl_1.34     Document Type: Article

References (23)

1. The TGF-β family and its composite receptors
2. Physiological actions and clinical applications of transforming growth factor-β (TGF-β)
3. Cytokines in kidney disease: The role of transforming growth factor beta
4. Suppression of experimental glomerulonephritis by antiserum against transforming growth factor β1
5. Natural inhibitor of transforming growth factor-β protects against scarring in experimental kidney disease
6. Gene therapy by skeletal muscle expression of decorin prevents fibrotic disease in rat kidney
7. Identification of a human endothelial cell antigen with monoclonal antibody 44G4 produced against a pre-B leukemic cell line
8. Regulated expression on human macrophages of endoglin, an Arg-Gly-Asp-containing surface antigen
9. Identification of distinct epitopes of endoglin, an RGD-containing glycoprotein of endothelial cells leukemic cells and syncytiotrophoblasts
10. Endoglin, a TGF-β binding protein of endothelial cells, is the gene for hereditary haemorragic telangiectasia type 1
11. Endoglin is a component of the transforming growth factor-β receptor system in human endothelial cells
12. Endoglin, a transforming growth factor-beta-binding protein, is upregulated in chronic progressive renal disease
13. Effect of trandolapril and verapamil on renal damage progression associated to 5/6 nephrectomy in rats
14. Expression of normal and truncated forms of human endoglin
15. Endoglin is expressed in the chicken vasculature and is involved in angiogenesis
16. Transforming growth factor beta 1 and renal injury following subtotal nephrectomy in the rat. Role of the renin-angiotensin system
17. Pathological expression of renin and angiotensin II in the renal tubule after subtotal nephrectomy. Implications for the pathogenesis of tubulointerstitial fibrosis
18. Endoglin modulates cellular responses to TGF-β1
19. Endoglin, a TGF-beta binding protein, is expressed by smooth muscle cells in human atherosclerotic plaques
20. Transforming growth factor beta in glomerular injury
21. Role of endoglin in cellular responses to transforming growth factor β. A comparative study with betaglycan
22. Endoglin is an accessory protein that interacts with the signaling receptor complex of multiple members of the transforming growth factor-β superfamily
23. The concept of glomerular self-defense