Assessment of cell type specific gene transfer of polyoma virus like particles presenting a tumor specific antibody Fv fragment

Journal of Virological Methods

Volumn 105, Issue 1, 2002, Pages 147-157

  May, Tobias ^a   Gleiter, Stefan ^a   Lilie, Hauke ^a  

^a MARTIN LUTHER UNIVERSITY HALLE WITTENBERG   (Germany)

Author keywords

Endosome; Fv fragment; Gene transfer; Polyionic peptides; Polyoma; Targeting; Virus like particle

Indexed keywords

ANTIGEN; CANCER ANTIBODY; DNA; TUMOR SPECIFIC ANTIBODY B3; UNCLASSIFIED DRUG; DNA BINDING PROTEIN; IMMUNOGLOBULIN FRAGMENT; RECOMBINANT PROTEIN; TRANSACTIVATOR PROTEIN; TRANSCRIPTION FACTOR; VEGETABLE PROTEIN; VP1 PROTEIN, PLANT;

ANTIBODY SPECIFICITY; ANTIGEN BINDING; ANTIGEN DETECTION; ANTIGEN EXPRESSION; ARTICLE; CONTROLLED STUDY; DEGRADATION; DNA MODIFICATION; DNA VECTOR; FLUORESCENCE MICROSCOPY; GENE TARGETING; GENE TRANSFER; HUMAN; HUMAN CELL; INTERNALIZATION; LYSOSOME; POLYOMA VIRUS; PRIORITY JOURNAL; PROTEIN TRANSPORT; TARGET CELL; TUMOR CELL; VIRUS PARTICLE; BREAST TUMOR; CARCINOMA; CELL CULTURE; EVALUATION; GENE THERAPY; GENE VECTOR; GENETICS; METABOLISM; METHODOLOGY; VIRION;

ANTIBODIES, NEOPLASM; ANTIBODY SPECIFICITY; BREAST NEOPLASMS; CARCINOMA; DNA-BINDING PROTEINS; GENE TARGETING; GENE THERAPY; GENE TRANSFER TECHNIQUES; GENETIC VECTORS; HUMAN; IMMUNOGLOBULIN FRAGMENTS; MICROSCOPY, FLUORESCENCE; POLYOMAVIRUS; RECOMBINANT PROTEINS; SUPPORT, NON-U.S. GOV'T; TRANSCRIPTION FACTORS; TUMOR CELLS, CULTURED; VIRION; HUMANS; PLANT PROTEINS; TRANS-ACTIVATORS;

POLYOMAVIRUS;

EID: 0035993314     PISSN: 01660934     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0166-0934(02)00099-X     Document Type: Article

References (38)

1. Cell-free assembly of a polyoma-like particle from empty capside and DNA
2. B3(Fv)-PE38KDEL, a single-chain immunotoxin that causes complete regression of a human carcinoma in mice
3. A recombinant immunotoxin containing a disulfide-stabilized Fv fragment
4. Immunotoxins against cancer
5. PH and the recycling of transferring during receptor-mediated endocytosis
6. Targeting human T cells by retroviral vectors displaying antibody domains selected from a phage display library
7. Polyoma virus pseudocapsids as efficient carriers of heterologous DNA into mammalian cells
8. A single-amino-acid substitution in polyomavirus VP1 correlates with plaque size and hemagglutination behavior
9. Changing the surface of a virus shell fusion of an enzyme to polyoma VP1
10. Coupling of antibodies via protein Z on modified polyoma virus-like particles
11. Inhibition of proteolytic degradation of low density lipoprotein in human fibroblasts by chloroquine, concanavalin A, and Triton WR 1339
12. Enhanced in vitro oligonucleotide and plasmid DNA transport by VP1 virus-like particles
13. Cell-type-specific gene transfer into human cells with retroviral vectors that display single-chain antibodies
14. Specific targeting to CD4+ cells of recombinant vesicular stomatitis viruses encoding human immunodeficiency virus envelope proteins
15. Targeting strategy for gene delivery to carcinoembryonic antigen- producing cancer cells by retrovirus displaying a single-chain variable fragment antibody
16. Sustained ex vivo and in vivo transfer of a reporter gene using polyoma virus pseudocapsids
17. Virus-like gene transfer into cells mediated by polyoma virus pseudocapsids
18. Immunotoxins in cancer therapy
19. Polyoma virus major capsid protein, VP1. Purification after high level expression in Escherichia coli
20. Characterization of the DNA-binding properties of the polyomavirus capsid protein VP1
21. Antibody-directed targeting of retroviral vectors via cell surface antigens
22. Amphotropic retroviral vectors displaying hepatocyte growth factor- envelope fusion proteins improve transduction efficiency of primary hepatocytes
23. Retrovirus vectors displaying the IgG-binding domain of protein A
24. Cell-specific targeting of Sindbis virus vectors displaying IgG-binding domains of protein A
25. Polyionic fusion peptides function as specific dimerization motifs
26. Caveolae are involved in the trafficking of mouse polyoma virions and artificial VP1 pseudocapsids towards cell nuclei
27. Viral vectors for gene therapy
28. Folding proteins
29. Self-assembly of purified polyomavirus capsid protein VP1
30. Polymorphism in the assembly of polyomavirus capsid protein VP1
31. Pseudotyping of murine leukemia virus with the envelope glycoproteins of HIV generates a retroviral vector with specificity of infection for CD4-expressing cells
32. Enhancement by polylysine of transient, but not stable, expression of genes carried into cells by polyoma VP1 pseudocapsids
33. Structure of murine polyomavirus complexed with an oligosaccharide receptor fragment
34. Crystal structures of murine polyomavirus in complex with straight- chain and branched-chain sialyloligosaccharide receptor fragments
35. Purification of a viral coat protein by an engineered polyionic sequence
36. Conjugation of an antibody Fv fragment to a virus coat protein: Cell- specific targeting of recombinant polyoma-virus-like particles
37. Mis-assembly of clathrin lattices on endosomes reveals a regulatory switch for coated pit formation
38. Attenuating the growth of tumors by intratumoral administration of DNA encoding Pseudomonas exotoxin via cationic liposomes