Estimating and evaluating the statistics of gapped local-alignment scores

Journal of Computational Biology

Volumn 9, Issue 3, 2002, Pages 575-593

  Bailey, Timothy L ^a   Gribskov, Michael ^a  

^a UNIVERSITY OF QUEENSLAND   (Australia)

Author keywords

Evaluation; Homology search; Sequence alignment; Statistics

Indexed keywords

ACCURACY; ALGORITHM; ARTICLE; EVALUATION; PRIORITY JOURNAL; SEQUENCE ALIGNMENT; SEQUENCE DATABASE; SEQUENCE HOMOLOGY; STATISTICS; BIOLOGY; CHEMISTRY; COMPUTER PROGRAM; COMPUTER SIMULATION; MATHEMATICAL COMPUTING; METHODOLOGY; PROBABILITY; SENSITIVITY AND SPECIFICITY; STATISTICAL MODEL;

ALGORITHMS; COMPUTATIONAL BIOLOGY; COMPUTER SIMULATION; MATHEMATICAL COMPUTING; MODELS, STATISTICAL; PROBABILITY; PROTEINS; SENSITIVITY AND SPECIFICITY; SEQUENCE ALIGNMENT; SOFTWARE;

PROTEIN;

EID: 0035991777     PISSN: 10665277     EISSN: None     Source Type: Journal    
DOI: 10.1089/106652702760138637     Document Type: Article

References (17)

1. Local alignment statistics
2. Gapped-BLAST and PSI-BLAST: A new generation of protein database search programs
3. The SWISS-PROT protein sequence database and its supplement TrEMBL in 2000
4. Assessing sequence comparison methods with reliable structurally identified distant evolutionary relationships
5. Multiple alignment using hidden Markov models
6. The use of receiver operating characteristic (ROC) analysis to evaluate sequence matching
7. Using the fisher kernel method to detect remote protein homologies
8. Methods for assessing the statistical significance of molecular sequence features by using general scoring schemes
9. Statistical Models and Methods for Lifetime Data
10. Maximum-likelihood estimation of statistical distributions of Smith-Waterman local sequence similarity scores
11. Approximate statistics of gapped alignments
12. Empirical statistical estimates for sequence similarity searches
13. Identification of common molecular subsequences
14. Statistics of large-scale sequence searching