The interleukin-1 receptor antagonist gene: A single-copy variant of the intron 2 variable number tandem repeat (VNTR) polymorphism

European Journal of Immunogenetics

Volumn 29, Issue 4, 2002, Pages 337-340

  Vamvakopoulos, J E ^a,b,e   Taylor, C J ^b   Morris Stiff, G J ^c   Green, C ^d   Metcalfe, S ^a  

^a UNIVERSITY OF CAMBRIDGE   (United Kingdom)

^b ADDENBROOKE S HOSPITAL   (United Kingdom)

^c CARDIFF UNIVERSITY   (United Kingdom)

^d NORTHWICK PARK INSTITUTE FOR MEDICAL RESEARCH   (United Kingdom)

^e Biomedicum Helsinki   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

INTERLEUKIN 1 RECEPTOR BLOCKING AGENT; IL1RN PROTEIN, HUMAN; INTERLEUKIN 1 RECEPTOR; SIALOGLYCOPROTEIN;

ARTICLE; GENE FREQUENCY; GENE IDENTIFICATION; GENETIC POLYMORPHISM; HUMAN; INTRON; NUCLEOTIDE REPEAT; NUCLEOTIDE SEQUENCE; PRIORITY JOURNAL; VARIABLE NUMBER OF TANDEM REPEAT; ADULT; ALTERNATIVE RNA SPLICING; DRUG ANTAGONISM; GENETICS; MALE; MOLECULAR GENETICS; POLYMERASE CHAIN REACTION;

ADULT; ALTERNATIVE SPLICING; BASE SEQUENCE; HUMAN; MALE; MINISATELLITE REPEATS; MOLECULAR SEQUENCE DATA; POLYMERASE CHAIN REACTION; POLYMORPHISM (GENETICS); RECEPTORS, INTERLEUKIN-1; SIALOGLYCOPROTEINS; SUPPORT, NON-U.S. GOV'T; HUMANS; INTERLEUKIN 1 RECEPTOR ANTAGONIST PROTEIN; POLYMORPHISM, GENETIC;

EID: 0035991729     PISSN: 09607420     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-2370.2002.00319.x     Document Type: Article

References (31)

1. Intrinsic polymorphism of variable number tandem repeat loci in the human genome
2. Genetic polymorphism of human interleukin-1alpha
3. Characterisation of polymorphisms of an interleukin 1 receptor type 1 gene (IL1RI) promotor region (P2) and their relation to insulin-dependent diabetes mellitus (IDDM). The Danish Study Group of Diabetes in Childhood
4. Interleukin-1 receptor antagonist gene polymorphism as a disease severity factor in systemic lupus erythematosus
5. Association of Graves' disease with an allele of the interleukin-1 receptor antagonist gene
6. Interleukin-1 receptor antagonist allele (IL1RN*2) associated with nephropathy in diabetes mellitus
7. Interleukin 1 receptor antagonist gene polymorphism association with lichen sclerosus
8. Novel interleukin-1 receptor antagonist exon polymorphisms and their use in allele-specific mRNA assessment
9. An analysis of linkage disequilibrium in the interleukin-1 gene cluster, using a novel grouping method for multiallelic markers
10. Cytokine production by normal human monocytes: Inter-subject variation and relationship to an IL-1 receptor antagonist (IL-1Ra) gene polymorphism
11. Interleukin-1 receptor antagonist expression in human endothelial cells and atherosclerosis
12. Nucleotide sequence analysis of the apolipoprotein B 3′VNTR
13. Interleukin-1 polymorphisms associated with increased risk of gastric cancer
14. Single base polymorphism at - 511 in the human interleukin-1beta gene (IL-1beta)
15. Five novel intragenic dimorphisms in the human interleukin-1 genes combine to high informativity
16. Polymorphisms in IL-1beta and IL-1 receptor antagonist genes are associated with myasthenia gravis
17. IL-1 receptor antagonist (IL-1Ra) plasma levels are co-ordinately regulated by both IL-1Ra and IL-1beta genes
18. Somatic mutation processes at a human minisatellite
19. Complex gene conversion events in germline mutation at human minisatellites
20. Hypervariable 'minisatellite' regions in human DNA
21. High-resolution mapping of crossovers in human sperm defines a minisatellite-associated recombination hotspot
22. Repeat instability at human minisatellites arising from meiotic recombination
23. IL-1 receptor antagonist (IL-1RA) gene polymorphism in Sjogren's syndrome and rheumatoid arthritis
24. A TaqI polymorphism in the human interleukin-1 beta (IL-1 beta) gene correlates with IL-1 beta secretionin vitro
25. Genetic relationship between the 3′-VNTR and diallelic apolipoprotein B gene polymorphisms: Haplotype analysis in individuals of European and south Asian origin
26. Allele diversity and germline mutation at the insulin minisattelite
27. Polymorphism in human IL-1 receptor antagonist gene intron 2 is caused by variable numbers of an 86-bp tandem repeat
28. Dinucleotide repeat polymorphism in the human interleukin 1 alpha gene (IL1A)
29. Influence of polymorphism in the genes for the interleukin (IL)-1 receptor antagonist and IL-1beta on tuberculosis
30. Unequal crossingover between homologous chromosomes is not the major mechanism involved in the generation of new alleles at VNTR loci
31. A high frequency of length polymorphisms in repeated sequences adjacent to Alu sequences