Antibiotics for the treatment of onchocerciasis and other filarial infections

Current Opinion in Investigational Drugs

Volumn 3, Issue 4, 2002, Pages 533-537

  Hoerauf, Achim ^a   Adjei, Ohene ^a   Büttner, Dietrich W ^a  

^a BERNHARD NOCHT INSTITUTE FOR TROPICAL MEDICINE   (Germany)

Author keywords

Doxycycline; Filiariasis; Ivermectin; Onchocerciasis; Wolbachia

Indexed keywords

ALBENDAZOLE; AMOCARZINE; ANTIBIOTIC AGENT; ANTIFILARIAL AGENT; AZITHROMYCIN; BENZIMIDAZOLE DERIVATIVE; CASSIA EXTRACT; CASSIA FIKIFIKI EXTRACT; CHLORAMPHENICOL; DIETHYLCARBAMAZINE; DOXYCYCLINE; IVERMECTIN; MEBENDAZOLE; MELARSOPROL; METRIFONATE; ORGANOPHOSPHATE; RIFAMPICIN; SURAMIN; TETRACYCLINE DERIVATIVE; UNCLASSIFIED DRUG;

BRUGIA; CASSIA FIKIFIKI; CLINICAL TRIAL; DOSE RESPONSE; DRUG COST; DRUG EFFICACY; DRUG INDICATION; EMBRYO DEVELOPMENT; EYE DISEASE; FILARIA; FILARIASIS; HUMAN; INFECTION CONTROL; LONG TERM CARE; MEDICINAL PLANT; NONHUMAN; ONCHOCERCA VOLVULUS; ONCHOCERCIASIS; PUBLIC HEALTH; REVIEW; RICKETTSIA; SYMBIONT; SYSTEMIC DISEASE; WOLBACHIA; WUCHERERIA BANCROFTI; ANIMAL; DRUG EFFECT; DRUG RESISTANCE; MICROBIOLOGY; ONCHOCERCA; PARASITOLOGY; SYMBIOSIS;

ANIMAL; BRUGIA; DOXYCYCLINE; DRUG RESISTANCE; FILARIASIS; FILARICIDES; HUMAN; ONCHOCERCA; ONCHOCERCIASIS; SUPPORT, NON-U.S. GOV'T; SYMBIOSIS; WOLBACHIA; WUCHERERIA BANCROFTI; ANIMALS; HUMANS;

EID: 0035988833     PISSN: 14724472     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review

References (40)

1. Onchocerciasis and its control
2. Strategies and tools for the control/elimination of lymphatic filariasis
3. How is eradication to be defined and what are the biological criteria?
4. Control of onchocerciasis today: Status and challenges
5. Programmatic goals and approaches to onchocerciasis
6. Onchocerciasis control strategies
7. Ivermectin as an antiparasitic agent for use in humans
8. Ivermectin. A review of its antifilarial activity, pharmacokinetic properties and clinical efficacy in onchocerciasis
9. The chemotherapy of onchocerciasis XX: Ivermectin in combination with albendazole
10. The reproductive lifespan of Onchocerca volvulus in West African savanna
11. Histological examination of onchocercomata after therapy with ivermectin
12. WHO Expert Committee on Onchocerciasis
13. The global programme to eliminate lymphatic filariasis
14. Current status and future prospects of the Global Lymphatic Filariasis Programme
15. The chemotherapy of onchocerciasis iii. A comparative study of diethylcarbamazine (DEC) and metrifonate
16. In vivo and in vitro effects of extracts from Cassia aubrevillei in onchocerciasis
17. Cassia fikifiki - Eine afrikanische heilpflanze gegen onchozerkose
18. The chemotherapy of onchocerciasis. XIV. Studies with mebendazole citrate
19. Control and surveillance of African trypanosomiasis
20. What is the real target for ivermectin resistance selection in Onchocerca volvulus?
21. Genetic variability following selection of Haemonchus contortus with anthelmintics
22. Wolbachia bacteria of filarial nematodes
23. Wolbachia bacteria of filarial nematodes: A target for control?
24. Call to consolidate achievements for onchocerciasis and lymphatic filariasis control
25. Phylogeny of Wolbachia in filarial nematodes
26. Tetracycline therapy targets intracellular bacteria in the filarial nematode Litomosoides sigmodontis and results in filarial infertility
27. Determination of Wolbachia genome size by pulsed-field gel electrophoresis
28. A new approach to the treatment of filariasis
29. Wolbachia in filarial nematodes: Evolutionary aspects and implications for the pathogenesis and treatment of filarial diseases
30. Effects of tetracycline on the filarial worms Brugia pahangi and Dirofilaria immitis and their bacterial endosymbionts Wolbachia
31. Antibiotics and Wolbachia in filarial nematodes: Antifilarial activity of rifampicin, oxytetracycline and chloramphenicol against Onchocerca gutturosa, Onchocerca lienalis and Brugia pahangi
32. Targeting of Wolbachia in Litomosoides sigmodontis: Comparison of tetracycline with chloramphenicol, macrolides and ciprofloxacin
33. Macrofilaricidal activity of tetracycline against the filarial nematode, Onchocerca ochengi: Elimination of Wolbachia precedes worm death and suggests a dependent relationship
34. Wolbachia and the antifilarial properties of tetracycline. An untold story
35. Tetracycline inhibits development of the infective-stage larvae of filarial nematodes in vitro
36. Endosymbiotic bacteria in worms as targets for a novel chemotherapy in filariasis
37. Depletion of Wolbachia endobacteria in Onchocerca volvulus by doxycycline and microfilaridermia after ivermectin treatment
38. Macrofilaricides and onchocerciasis control, mathematical modeling of the prospects for elimination
39. Relationships between the prevalence and intensity of Loa loa infection in the Central Province of Cameroon
40. Co-endemicity of loiasis and onchocerciasis in the South West Province of Cameroon: Implications for mass treatment with ivermectin