Targeting of Wolbachia endobacteria in Litomosoides sigmodontis: Comparison of tetracyclines with chloramphenicol, macrolides and ciprofloxacin

Tropical Medicine and International Health

Volumn 5, Issue 4, 2000, Pages 275-279

  Hoerauf, Achim ^a   Volkmann, Lars ^a   Nissen Paehle, Kerstin ^a   Schmetz, Christel ^a   Autenrieth, Ingo ^b   Büttner, Dietrich W ^a   Fleischer, Bernhard ^a  

^a BERNHARD NOCHT INSTITUTE FOR TROPICAL MEDICINE   (Germany)

^b NONE

Author keywords

Chloramphenicol; Endobacteria; Filariasis; Litomosoides sigmodontis; Macrolids; Tetracycline; Wolbachia

Indexed keywords

CHLORAMPHENICOL; CIPROFLOXACIN; ERYTHROMYCIN; TETRACYCLINE;

DISEASE CONTROL; NEMATODE; TARGETING;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTIBIOTIC SENSITIVITY; ARTICLE; COMPARATIVE STUDY; DRUG EFFICACY; DRUG MECHANISM; DRUG POTENCY; DRUG TARGETING; FILARIASIS; LITOMOSOIDES SIGMODONTIS; NONHUMAN; PARASITE DEVELOPMENT; RAT; WOLBACHIA;

ANIMALS; ANTI-BACTERIAL AGENTS; CHLORAMPHENICOL; CIPROFLOXACIN; DNA, BACTERIAL; FEMALE; FILARIASIS; FILARIOIDEA; INJECTIONS, INTRAPERITONEAL; MACROLIDES; MICE; MICE, INBRED BALB C; POLYMERASE CHAIN REACTION; TETRACYCLINE; WOLBACHIA;

ANIMALIA; FILARIA; LITOMOSOIDES SIGMODONTIS; NEGIBACTERIA; NEMATODA; PROTOZOA; RICKETTSIACEAE; RODENTIA; WOLBACHIA;

EID: 0034025396     PISSN: 13602276     EISSN: None     Source Type: Journal    
DOI: 10.1046/j.1365-3156.2000.00544.x     Document Type: Article

References (17)

1. Addiss D (1998) Global disease elimiation and eradication as public health strategies. Lymphatic Filariasis. Bulletin of the World Health Organization 76, 145-146.
2. Anhalt JP (1991) Assays for antimicrobial agents in body fluids. In: Manual of Clinical Microbiology (ed. A Balows), American Society for Microbiology, Washington DC, pp. 1192-1198.
3. Awadzi K, Addy ET, Opoku NO, Plenge-Bönig A & Büttner DW (1995) The chemotherapy of onchocerciasis XX: ivermectin in combination with albendazole. Tropical Medicine and Parasitology 46, 213-220.
4. Bandi C, McCall JW, Genchi C, Corona S, Venco L & Sacchi L (1999) Effects of tetracycline on the filarial worms Brugia pahangi and Dirofilaria immitis and their bacterial endosymbionts Wolbachia. International Journal of Parasitology 29, 357-364.
5. Fischer P, Büttner DW, Bamuhiiga J & Williams SA (1998) Detection of the filarial parasite Mansonella streptocerca in skin biopsies by a nested polymerase chain reaction-based assay. American Journal of Tropical Medicine and Hygiene 58, 816-820.
6. Henkle-Dührsen K, Eckelt V, Wildenburg G, Blaxter M & Walter RD (1998) Gene structure, activity and localization of a catalase from intracellular bacteria in Onchocerca volvulus. Molecular and Biochemical Parasitology 96, 69-81.
7. Hoerauf A, Nissen-Pähle K, Schmetz C et al. (1999) Tetracycline therapy targets intracellular bacteria in the filarial nematode Litomosoides sigmodontis and results in filarial infertility. Journal of Clinical Investigation 103, 11-18.
8. Hoerauf A, Volkmann L, Hamelmann C, Adjei O, Autenrieth I, Fleischer B & Büttner DW (2000) Endosymbiotic bacteria in worms - targets for a novel chemotherapeutical approach by antibiotics in human filariasis. Lancet 355, in press.
9. Plaisier AP, Alley ES, van Oortmarssen GJ, Boatin BA & Habbema JD (1997) Required duration of combined annual ivermectin treatment and vector control in the Onchocerciasis Control Programme in West Africa. Bulletin of the World Health Organization 75, 237-245.
10. Rachek LI, Tucker AM, Winkler HH & Wood DO (1998) Transformation of Rickettsia prowazekii to rifampin resistance. Journal of Bacteriology 180, 2118-2124.
11. Reiner SL, Zheng S, Corry DB & Locksley RM (1993) Constructing polycompetitor cDNAs for quantitative PCR. Journal of Immunological Methods 165, 37-46.
12. Richards FO, Miri E, Meredith S et al. (1998) Global disease elimiation and eradication as public health strategies. Onchocerciasis. Bulletin of the World Health Organization 76, 147-149.
13. Sahm DF & Washington JA (1991) Antibacterial susceptibility tests: dilution methods. In: Manual of Clinical Microbiology (ed. A Balows), American Society for Microbiology, Washington DC, pp. 1105-1116.
14. Sironi M, Bandi C, Sacchi L, Di Sacco B, Damiani C & Genchi C (1995) Molecular evidence for a close relative of the arthropod endosymbiont Wolbachia in a filarial worm. Molecular and Biochemical Parasitology 74, 223-227.
15. Taylor M, Bilo K, Cross HF, Archer JP & Underwood AP (1999) 16S rDNA phylogeny and ultrastructural characterization of Wolbachia intracellular bacteria of the filarial nematodes Brugia malayi, B. pahangi and Wuchereria bancrofti. Experimental Parasitology 91, 356-361.
16. Taylor M & Hoerauf A (1999) Wolbachia bacteria of filarial nematodes. Parasitology Today 15, 437-442.
17. Yao JDC & Moellering RC (1991) Antibacterial agents. In: Manual of Clinical Microbiology (ed. A Balows), American Society for Microbiology, Washington DC, pp. 1065-1098.